(Q40437372)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817479%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

Bcl-2 rescues ceramide- and etoposide-induced mitochondrial apoptosis through blockage of caspase-2 activation (English)

1 reference

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10 January 2020

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8

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10 January 2020

author name string

Chiou-Feng Lin

1

1 reference

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10 January 2020

Chia-Ling Chen

2

1 reference

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10 January 2020

Wen-Tsan Chang

3

1 reference

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10 January 2020

Ming-Shiou Jan

4

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10 January 2020

Li-Jin Hsu

5

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10 January 2020

Ren-Huang Wu

6

1 reference

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10 January 2020

Yi-Ting Fang

7

1 reference

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10 January 2020

Wen-Chang Chang

9

1 reference

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10 January 2020

Yee-Shin Lin

10

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10 January 2020

language of work or name

English

0 references

publication date

6 April 2005

1 reference

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Journal of Biological Chemistry

10 January 2020

published in

1 reference

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10 January 2020

volume

280

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10 January 2020

issue

25

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10 January 2020

page(s)

23758-23765

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Mitochondria and apoptosis

10 January 2020

cites work

1 reference

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Mitochondrial control of cell death

21 January 2018

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Mitochondria, the killer organelles and their weapons

21 January 2018

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21 January 2018

Bcl-2 family proteins

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

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Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator

21 January 2018

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

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Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

21 January 2018

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During apoptosis bcl-2 changes membrane topology at both the endoplasmic reticulum and mitochondria

21 January 2018

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Bcl-2 phosphorylation required for anti-apoptosis function

21 January 2018

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A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis

21 January 2018

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Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria

21 January 2018

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Caspase-2 can trigger cytochrome C release and apoptosis from the nucleus.

21 January 2018

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Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

21 January 2018

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Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

21 January 2018

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Apoptosis. A cinderella caspase takes center stage

21 January 2018

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Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway

21 January 2018

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21 January 2018

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Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9

21 January 2018

1 reference

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A novel Apaf-1-independent putative caspase-2 activation complex

21 January 2018

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The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

21 January 2018

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Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells

21 January 2018

1 reference

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Sequential caspase-2 and caspase-8 activation upstream of mitochondria during ceramideand etoposide-induced apoptosis.

21 January 2018

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Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

21 January 2018

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Bcl-2 interrupts the ceramide-mediated pathway of cell death.

21 January 2018

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prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2.

21 January 2018

1 reference

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Bcl-2 inhibits early apoptotic events and reveals post-mitotic multinucleation without affecting cell cycle arrest in human epithelial tumor cells exposed to etoposide.

21 January 2018

1 reference

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Inhibition of caspases inhibits the release of apoptotic bodies: Bcl-2 inhibits the initiation of formation of apoptotic bodies in chemotherapeutic agent-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412292200

Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis

21 January 2018

1 reference

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Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells.

21 January 2018

1 reference

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Bcl-2 prevents abnormal mitochondrial proliferation duringetoposide-induced apoptosis

21 January 2018

1 reference

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Involvement of Bcl-2 cleavage in the acceleration of VP-16-induced U937 cell apoptosis

21 January 2018

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The temporal relationship between protein phosphatase, ICE/CED-3 proteases, intracellular acidification, and DNA fragmentation in apoptosis

21 January 2018

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The involvement of protein phosphatases in the activation of ICE/CED-3 protease, intracellular acidification, DNA digestion, and apoptosis

21 January 2018

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A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

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Signal transduction of stress via ceramide

21 January 2018

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Ceramide in the eukaryotic stress response

21 January 2018

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Inhibition of Fas-induced apoptosis by Bcl-2.

21 January 2018

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Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

21 January 2018

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Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor

21 January 2018

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Antisense RNA down-regulation of bcl-2 expression in DU145 prostate cancer cells does not diminish the cytostatic effects of G3139 (Oblimersen).

21 January 2018

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Need for caspase-2 in apoptosis of growth-factor-deprived PC12 cells

21 January 2018

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Raft ceramide in molecular medicine

21 January 2018

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Biologically active sphingolipids in cancer pathogenesis and treatment

21 January 2018

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Common regulation of apoptosis signaling induced by CD95 and the DNA-damaging stimuli etoposide and gamma-radiation downstream from caspase-8 activation

21 January 2018

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Ceramide-induced cell death in primary neuronal cultures: upregulation of ceramide levels during neuronal apoptosis

21 January 2018

1 reference

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Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3β, and induction of the mitochondrial-dependent intrinsic caspase pathway

21 January 2018

1 reference

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Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis

21 January 2018

1 reference

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Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473.

21 January 2018

1 reference

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Intracellular signal transduction pathways activated by ceramide and its metabolites

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M412292200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15817479%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference