(Q40443869)

20 September 2017

PTPL1 is a direct transcriptional target of EWS-FLI1 and modulates Ewing's Sarcoma tumorigenesis (English)

1 reference

20 September 2017

Ogan D Abaan

1

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20 September 2017

Amy Levenson

2

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20 September 2017

Osman Khan

3

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20 September 2017

Priscilla A Furth

4

1 reference

20 September 2017

Aykut Uren

5

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20 September 2017

Jeffrey A Toretsky

6

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20 September 2017

language of work or name

English

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publication date

1 April 2005

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20 September 2017

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20 September 2017

24

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20 September 2017

16

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20 September 2017

2715-2722

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208247

20 September 2017

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cites work

Membrane targeting of protein tyrosine phosphatase PTPL1 through its FERM domain via binding to phosphatidylinositol 4,5-biphosphate.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

Protein-tyrosine phosphatase PTPL1/FAP-1 triggers apoptosis in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

Molecular biology of the Ewing's sarcoma/primitive neuroectodermal tumor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

Tyrosine phosphorylation of I kappa B alpha activates NF kappa B through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

Temporal pattern of NFkappaB activation influences apoptotic cell fate in a stimuli-dependent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

Tyrosine phosphatase-epsilon activates Src and supports the transformed phenotype of Neu-induced mammary tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

ZRP-1, a zyxin-related protein, interacts with the second PDZ domain of the cytosolic protein tyrosine phosphatase hPTP1E

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

Identification of p21WAF1/CIP1 as a direct target of EWS-Fli1 oncogenic fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

The insulin-like growth factor-I receptor is required for EWS/FLI-1 transformation of fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

Analysis of the expression of cell cycle regulators in Ewing cell lines: EWS-FLI-1 modulates p57KIP2and c-Myc expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

Upregulation of Id2, an oncogenic helix-loop-helix protein, is mediated by the chimeric EWS/ets protein in Ewing sarcoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

Identification of two Fas-associated phosphatase-1 (FAP-1) promoters in human cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

mRNA expression of Fas receptor (CD95)-associated proteins (Fas-associated phosphatase-1/FAP-1, Fas-associating protein with death domain/FADD, and receptor-interacting protein/RIP) in human leukaemia/lymphoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

In vivo expression of soluble Fas and FAP-1: possible mechanisms of Fas resistance in human hepatoblastomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

Fas-mediated apoptosis in Ewing's sarcoma cell lines by metalloproteinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

Characterization of the interactions between PDZ domains of the protein-tyrosine phosphatase PTPL1 and the carboxyl-terminal tail of Fas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

A novel GTPase-activating protein for Rho interacts with a PDZ domain of the protein-tyrosine phosphatase PTPL1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

Induction of tenascin-C by tumor-specific EWS-ETS fusion genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208247

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208247

1 reference

Dimensions Publication ID

20 September 2017

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1 reference