(Q40451946)

20 September 2017

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title

Inhibition of gene expression with ribozymes. (English)

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20 September 2017

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P Marschall

1

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20 September 2017

J B Thomson

series ordinal

2

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20 September 2017

F Eckstein

series ordinal

3

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20 September 2017

1 October 1994

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Cellular and Molecular Neurobiology

20 September 2017

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20 September 2017

14

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20 September 2017

5

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20 September 2017

523-538

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https://scigraph.springernature.com/pub.10.1007/bf02088835

20 September 2017

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cites work

The hammerhead RNA domain, a model ribozyme

1 reference

https://api.crossref.org/works/10.1007%2FBF02088835

Ribozyme, antisense RNA, and antisense DNA inhibition of U7 small nuclear ribonucleoprotein-mediated histone pre-mRNA processing in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02088835

Modification of antisense phosphodiester oligodeoxynucleotides by a 5' cholesteryl moiety increases cellular association and improves efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02088835

RNA enzymes (ribozymes) as antiviral therapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02088835

The in vivo application of ribozymes

21 January 2018

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12 December 2020

Incorporation of the catalytic domain of a hammerhead ribozyme into antisense RNA enhances its inhibitory effect on the replication of human immunodeficiency virus type 1.

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12 December 2020

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12 December 2020

High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.

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12 December 2020

Antisense oligonucleotide inhibition of acetylcholinesterase gene expression induces progenitor cell expansion and suppresses hematopoietic apoptosis ex vivo.

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12 December 2020

Kinetics and mechanisms for removal of circulating single-stranded DNA in mice

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12 December 2020

Intracellular distribution of microinjected antisense oligonucleotides

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12 December 2020

Ribozymes as anti-HIV-1 therapeutic agents: principles, applications, and problems

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12 December 2020

Ribozymes designed to inhibit transformation of NIH3T3 cells by the activated c-Ha-ras gene

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12 December 2020

Self-cleaving catalytic RNA.

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12 December 2020

Cytoplasmic delivery of ribozymes leads to efficient reduction in alpha-lactalbumin mRNA levels in C127I mouse cells

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12 December 2020

RNA enzyme-directed gene therapy

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12 December 2020

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12 December 2020

What makes an mRNA anti-sense-itive?

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12 December 2020

Nuclease-resistant chimeric ribozymes containing deoxyribonucleotides and phosphorothioate linkages

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12 December 2020

High activity and stability of hammerhead ribozymes containing 2'-modified pyrimidine nucleosides and phosphorothioates

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12 December 2020

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12 December 2020

Nuclease resistant ribozymes with high catalytic activity

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12 December 2020

Enhancement of ribozyme catalytic activity by a contiguous oligodeoxynucleotide (facilitator) and by 2'-O-methylation

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12 December 2020

Extended target-site specificity for a hammerhead ribozyme

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12 December 2020

Protein enhancement of hammerhead ribozyme catalysis

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12 December 2020

Chimeric DNA-RNA hammerhead ribozymes have enhanced in vitro catalytic efficiency and increased stability in vivo

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12 December 2020

Antisense effect of oligodeoxynucleotides with inverted terminal internucleotidic linkages: a minimal modification protecting against nucleolytic degradation

1 reference

12 December 2020

Intracellular immunization of human T cells with a hairpin ribozyme against human immunodeficiency virus type 1.

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12 December 2020

Ribozyme mediated destruction of RNA in vivo

1 reference

12 December 2020

A kinetic and thermodynamic framework for the hammerhead ribozyme reaction

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12 December 2020

Human gene therapy comes of age.

1 reference

12 December 2020

Generating loss-of-function phenotypes of the fushi tarazu gene with a targeted ribozyme in Drosophila.

1 reference

12 December 2020

Activity of hammerhead ribozymes containing non-nucleotidic linkers

1 reference

12 December 2020

Self-splicing of group I introns

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12 December 2020

Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme

1 reference

12 December 2020

The basic science of gene therapy

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12 December 2020

Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA.

1 reference

12 December 2020

Comparison of the properties of ribonucleases in human liver tissue and serum

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12 December 2020

Numbering system for the hammerhead

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12 December 2020

Ribozymes as potential anti-HIV-1 therapeutic agents.

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12 December 2020

Ribozyme cleaves rex/tax mRNA and inhibits bovine leukemia virus expression

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12 December 2020

Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes

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12 December 2020

Kinetic Characterization of Ribonuclease-Resistant 2′-Modified Hammerhead Ribozymes

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12 December 2020

Substrate Specificity and Kinetics of Degradation of Antisense Oligonucleotides by a 3′ Exonuclease in Plasma

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12 December 2020

Comparison of different ribozymes for efficient and specific cleavage of BCR/ABL related mRNAs.

1 reference

12 December 2020

AUA-cleaving hammerhead ribozymes: attempted selection for improved cleavage

1 reference

12 December 2020

Antisense oligonucleotides as therapeutic agents--is the bullet really magical?

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12 December 2020

Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA.

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12 December 2020

Hammerhead ribozyme-mediated cleavage of the long terminal repeat RNA of human immunodeficiency virus type 1.

1 reference

12 December 2020

Attenuation of white gene expression in transgenic Drosophila melanogaster: possible role of a catalytic antisense RNA.

1 reference

12 December 2020

Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication--potential effectiveness against most presently sequenced HIV-1 isolates

1 reference

12 December 2020

Essential nucleotide sequences and secondary structure elements of the hairpin ribozyme

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12 December 2020

Preformed ribozyme destroys tumour necrosis factor mRNA in human cells

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12 December 2020

Can hammerhead ribozymes be efficient tools to inactivate gene function?

1 reference

12 December 2020

Inhibition of axonal growth by SNAP-25 antisense oligonucleotides in vitro and in vivo.

1 reference

12 December 2020

2'-Fluoro- and 2'-amino-2'-deoxynucleoside 5'-triphosphates as substrates for T7 RNA polymerase

1 reference

12 December 2020

The cleavage specificity of RNase III.

1 reference

12 December 2020

Gephyrin antisense oligonucleotides prevent glycine receptor clustering in spinal neurons.

1 reference

12 December 2020

Inhibition of HIV-1 replication by ribozymes that show poor activity in vitro.

1 reference

12 December 2020

Selection of guide sequences that direct efficient cleavage of mRNA by human ribonuclease P.

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12 December 2020

Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain

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12 December 2020

Ribozyme-mediated cleavage of c-fos mRNA reduces gene expression of DNA synthesis enzymes and metallothionein

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12 December 2020

Reversal of the malignant phenotype by an anti-ras ribozyme

1 reference

12 December 2020

Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells

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12 December 2020

Resistance to human immunodeficiency virus type 1 (HIV-1) infection in human CD4+ lymphocyte-derived cell lines conferred by using retroviral vectors expressing an HIV-1 RNA-specific ribozyme.

1 reference

12 December 2020

Ribozyme-mediated inhibition of bcr-abl gene expression in a Philadelphia chromosome-positive cell line.

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12 December 2020

Current concepts in antisense drug design

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12 December 2020

Sequence requirements of the hammerhead RNA self-cleavage reaction

1 reference

12 December 2020

A small catalytic oligoribonucleotide

1 reference

12 December 2020

Prevention of human immunodeficiency virus type 1 integrase expression in Escherichia coli by a ribozyme

1 reference

12 December 2020

Dynamics of the internalization of phosphodiester oligodeoxynucleotides in HL60 cells

1 reference

12 December 2020

Simple RNA enzymes with new and highly specific endoribonuclease activities

1 reference

12 December 2020

Synthesis and physical properties ofanti-HIV antisense oligonucleotides bearing terminal lipophilic groups

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02088835

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Dimensions Publication ID

20 September 2017

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