(Q40453548)

English

The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model.

scientific article published on April 2005

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scholarly article

1 reference

Europe PubMed Central

20 September 2017

The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model. (English)

1 reference

Europe PubMed Central

20 September 2017

colon carcinoma

1 reference

based on heuristic

inferred from title

author name string

Meghan E Minard

1

1 reference

Europe PubMed Central

20 September 2017

Matthew H Herynk

2

1 reference

Europe PubMed Central

20 September 2017

John G Collard

3

1 reference

Europe PubMed Central

20 September 2017

Gary E Gallick

4

1 reference

Europe PubMed Central

20 September 2017

language of work or name

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publication date

1 April 2005

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

24

1 reference

Europe PubMed Central

20 September 2017

2568-2573

1 reference

Europe PubMed Central

20 September 2017

15

1 reference

Europe PubMed Central

20 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1208503

0 references

Tiam1 overexpression potentiates heregulin-induced lymphoid enhancer factor-1/beta -catenin nuclear signaling in breast cancer cells by modulating the intercellular stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

21 January 2018

Expression of Tiam-1 in the developing brain suggests a role for the Tiam-1-Rac signaling pathway in cell migration and neurite outgrowth.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

21 January 2018

Down-regulation of vascular endothelial growth factor in a human colon carcinoma cell line transfected with an antisense expression vector specific for c-src

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

21 January 2018

Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

21 January 2018

Validation of a model of colon cancer progression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

21 January 2018

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

21 January 2018

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

21 January 2018

Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

21 January 2018

Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

21 January 2018

Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

21 January 2018

Prevalence of ras gene mutations in human colorectal cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

7 January 2021

based on heuristic

inferred from DOI database lookup

Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

7 January 2021

based on heuristic

inferred from DOI database lookup

CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

7 January 2021

based on heuristic

inferred from DOI database lookup

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

7 January 2021

based on heuristic

inferred from DOI database lookup

A role for Rac in Tiam1-induced membrane ruffling and invasion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

7 January 2021

based on heuristic

inferred from DOI database lookup

Src activation regulates anoikis in human colon tumor cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208503

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1208503

1 reference

Europe PubMed Central

20 September 2017

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0 references

1 reference

Europe PubMed Central

20 September 2017

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