(Q40454778)

20 September 2017

An enriched structural kinase database to enable kinome-wide structure-based analyses and drug discovery (English)

1 reference

20 September 2017

1 reference

1 reference

Natasja Brooijmans

1

1 reference

20 September 2017

Yu-Wei Chang

2

1 reference

20 September 2017

Dominick Mobilio

3

1 reference

20 September 2017

Rajiah A Denny

4

1 reference

20 September 2017

Christine Humblet

5

1 reference

20 September 2017

1 April 2010

1 reference

20 September 2017

1 reference

20 September 2017

19

1 reference

20 September 2017

4

1 reference

20 September 2017

763-774

1 reference

A structural informatics approach to mine kinase knowledge bases.

20 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Targeting cancer with small molecule kinase inhibitors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

The development of HKI-272 and related compounds for the treatment of cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Classifying protein kinase structures guides use of ligand-selectivity profiles to predict inactive conformations: structure of lck/imatinib complex

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Extra precision glide: docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

High affinity targets of protein kinase inhibitors have similar residues at the positions energetically important for binding

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

TM-align: a protein structure alignment algorithm based on the TM-score

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

The RCSB Protein Data Bank: a redesigned query system and relational database based on the mmCIF schema

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

High-throughput docking as a source of novel drug leads

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Dynamic features of cAMP-dependent protein kinase revealed by apoenzyme crystal structure

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Relibase: design and development of a database for comprehensive analysis of protein-ligand interactions

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

The protein kinase complement of the human genome

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Protein kinases--the major drug targets of the twenty-first century?

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

SACS--self-maintaining database of antibody crystal structure information.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Profile hidden Markov models

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

The art and practice of structure-based drug design: A molecular modeling perspective

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Kinase domain mutations in cancer: implications for small molecule drug design strategies.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

CREDO: a protein-ligand interaction database for drug discovery.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Fragment-based drug design: how big is too big?

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Did protein kinase regulatory mechanisms evolve through elaboration of a simple structural component?

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Use of Relibase for retrieving complex three-dimensional interaction patterns including crystallographic packing effects

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

BindingDB: a web-accessible molecular recognition database

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867016

Database diversity assessment: new ideas, concepts, and tools

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20135687

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Binding MOAD (Mother Of All Databases)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20135687

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MEROPS: the peptidase database

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20135687

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/PRO.355

1 reference

20 September 2017

1 reference

20 September 2017

PubMed publication ID

20135687

1 reference