(Q40456348)

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Does Viperin Function as a Radical S-Adenosyl-l-methionine-dependent Enzyme in Regulating Farnesylpyrophosphate Synthase Expression and Activity?

scientific article published on 10 November 2016

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27834682%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

Does Viperin Function as a Radical S-Adenosyl-l-methionine-dependent Enzyme in Regulating Farnesylpyrophosphate Synthase Expression and Activity? (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27834682%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

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27 March 2020

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Caitlyn Makins

1

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27 March 2020

Soumi Ghosh

2

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27 March 2020

Gabriel D Román-Meléndez

3

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27 March 2020

Robert T Kennedy

5

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27 March 2020

E Neil G Marsh

6

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27 March 2020

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10 November 2016

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27 March 2020

Journal of Biological Chemistry

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27 March 2020

291

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27 March 2020

52

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27 March 2020

26806-26815

1 reference

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27 March 2020

Radical S-Adenosylmethionine Enzymes in Human Health and Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Benzoyl chloride derivatization with liquid chromatography-mass spectrometry for targeted metabolomics of neurochemicals in biological samples

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Archaeal Elp3 catalyzes tRNA wobble uridine modification at C5 via a radical mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Recent advances in radical SAM enzymology: new structures and mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Radical S-adenosylmethionine enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Viperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

High-resolution crystal structure of the eukaryotic HMP-P synthase (THIC) from Arabidopsis thaliana

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

The role of viperin in the innate antiviral response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Viperin regulates cellular lipid metabolism during human cytomegalovirus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Radical S-adenosylmethionine enzyme catalyzed thioether bond formation in sactipeptide biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Radical mediated ring formation in the biosynthesis of the hypermodified tRNA base wybutosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Radical SAM-mediated methylation reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Viperin is induced following dengue virus type-2 (DENV-2) infection and has anti-viral actions requiring the C-terminal end of viperin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

N-terminal protein processing: a comparative proteogenomic analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Mechanistic studies of the spore photoproduct lyase via a single cysteine mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

HIV-1 infection of human macrophages directly induces viperin which inhibits viral production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

The presence of the iron-sulfur motif is important for the conformational stability of the antiviral protein, Viperin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Biotin synthase: insights into radical-mediated carbon-sulfur bond formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Tryptophan tryptophylquinone biosynthesis: a radical approach to posttranslational modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Viperin: a multifunctional, interferon-inducible protein that regulates virus replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Radical SAM enzymes in the biosynthesis of sugar-containing natural products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

ELP3 controls active zone morphology by acetylating the ELKS family member Bruchpilot

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Radical-mediated enzymatic methylation: a tale of two SAMS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

The antiviral protein viperin inhibits hepatitis C virus replication via interaction with nonstructural protein 5A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Antiviral protein Viperin promotes Toll-like receptor 7- and Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Structural insights into radical generation by the radical SAM superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Radicals from S-adenosylmethionine and their application to biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Adenosyl radical: reagent and catalyst in enzyme reactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

The antiviral protein viperin is a radical SAM enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

The interferon-inducible protein viperin inhibits influenza virus release by perturbing lipid rafts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Characterization of MOCS1A, an oxygen-sensitive iron-sulfur protein involved in human molybdenum cofactor biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

30 June 2018

Purification and characterization of the human elongator complex

1 reference

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30 June 2018

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1 reference

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30 June 2018

An iron-sulfur cluster domain in Elp3 important for the structural integrity of elongator.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5207188

20 August 2018

The Radical SAM Superfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/27834682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An organic radical in the lysine 2,3-aminomutase reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/27834682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M116.751040

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27834682%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27834682%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27834682%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

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