(Q40461283)

20 September 2017

title

Dimerization through the catalytic domain is essential for MEKK2 activation. (English)

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20 September 2017

Jinke Cheng

1

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20 September 2017

Ling Yu

2

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20 September 2017

Dongyu Zhang

3

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20 September 2017

Qiaojia Huang

4

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20 September 2017

David Spencer

5

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20 September 2017

Bing Su

6

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20 September 2017

language of work or name

English

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publication date

4 February 2005

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Journal of Biological Chemistry

20 September 2017

published in

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20 September 2017

volume

280

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20 September 2017

issue

14

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20 September 2017

page(s)

13477-13482

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A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Disruption of Mekk2 in mice reveals an unexpected role for MEKK2 in modulating T-cell receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Mekk3 is essential for early embryonic cardiovascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

The essential role of MEKK3 in TNF-induced NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

MEKK2 regulates the coordinate activation of ERK5 and JNK in response to FGF-2 in fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

JNK is involved in signal integration during costimulation of T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Molecular cloning and characterization of a human protein kinase that specifically activates c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Improved artificial death switches based on caspases and FADD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Dimerization of cell surface receptors in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

TGF-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Controlling signal transduction with synthetic ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Membrane localization, oligomerization, and phosphorylation are required for optimal raf activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

Molecular recognition in dimerization between PB1 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M414258200

21 January 2018

Identifiers

DOI

10.1074/JBC.M414258200

1 reference

20 September 2017

1 reference