(Q40461294)

20 September 2017

Alpha,beta-unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor gamma. (English)

1 reference

20 September 2017

Takuma Shiraki

1

1 reference

20 September 2017

Narutoshi Kamiya

2

1 reference

20 September 2017

Sayaka Shiki

3

1 reference

20 September 2017

Takashi S Kodama

4

1 reference

20 September 2017

Akira Kakizuka

5

1 reference

20 September 2017

Hisato Jingami

6

1 reference

20 September 2017

language of work or name

English

0 references

publication date

4 February 2005

1 reference

Journal of Biological Chemistry

20 September 2017

1 reference

20 September 2017

280

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20 September 2017

14145-14153

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20 September 2017

14

1 reference

Orphan nuclear receptors: shifting endocrinology into reverse

20 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Peroxisome proliferator-activated receptor gamma and metabolic disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Crystal structure of the ligand binding domain of the human nuclear receptor PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Structure of the PPARalpha and -gamma ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Molecular recognition of fatty acids by peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Molecular basis for the direct inhibition of AP-1 DNA binding by 15-deoxy-Delta 12,14-prostaglandin J2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

L-764406 is a partial agonist of human peroxisome proliferator-activated receptor gamma. The role of Cys313 in ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Activation of orphan nuclear constitutive androstane receptor requires subnuclear targeting by peroxisome proliferator-activated receptor gamma coactivator-1 alpha. A possible link between xenobiotic response and nutritional state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Rational discovery of a novel interface for a coactivator in the peroxisome proliferator-activated receptor gamma: theoretical implications of impairment in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Microarray analysis of peroxisome proliferator-activated receptor-gamma induced changes in gene expression in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Protein thiol modification by 15-deoxy-Delta12,14-prostaglandin J2 addition in mesangial cells: role in the inhibition of pro-inflammatory genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

The two-step model of prostaglandin signal termination: in vitro reconstitution with the prostaglandin transporter and prostaglandin 15 dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

Oxidative stress stimulates the synthesis of the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid by inflammatory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

15-deoxy-Δ12,14-PGJ2: endogenous PPARγ ligand or minor eicosanoid degradation product?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500901200

21 January 2018

Identifiers

DOI

10.1074/JBC.M500901200

1 reference

20 September 2017

1 reference