(Q40489458)

21 September 2017

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title

Quinolone mode of action--new aspects (English)

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21 September 2017

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Hooper DC

1

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21 September 2017

1 January 1993

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21 September 2017

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21 September 2017

45 Suppl 3

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21 September 2017

8-14

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Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase alpha primase complex, topoisomerases I and II, and growth of mammalian lymphoblasts

21 September 2017

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12 December 2020

DNA gyrase: structure and function.

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12 December 2020

Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes

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12 December 2020

Protein- and RNA-synthesis independent bactericidal activity of ciprofloxacin that involves the A subunit of DNA gyrase

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12 December 2020

Effects of quinolones on nucleoid segregation in Escherichia coli

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12 December 2020

Quinolone-resistant mutations of the gyrA gene of Escherichia coli.

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12 December 2020

Role of autolysins in the activities of imipenem and CGP 31608, a novel penem, against slowly growing bacteria

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12 December 2020

Induction of calf thymus topoisomerase II-mediated DNA breakage by the antibacterial isothiazoloquinolones A-65281 and A-65282

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12 December 2020

Purification and characterization of DNA topoisomerase IV in Escherichia coli

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12 December 2020

Mutants of Escherichia coli K-12 exhibiting reduced killing by both quinolone and beta-lactam antimicrobial agents

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12 December 2020

Mode of action of the new quinolones: New data

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12 December 2020

Deoxyribonucleic acidgyrase-deoxyribonucleic acid complex containing 140 base pairs of deoxyribonucleic acid and an .alpha.2.beta.2 protein core

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12 December 2020

DNA supercoiling and relaxation by ATP-dependent DNA topoisomerases

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12 December 2020

The parD- mutant of Escherichia coli also carries a gyrAam mutation. The complete sequence of gyrA

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12 December 2020

Lytic effect of two fluoroquinolones, ofloxacin and pefloxacin, on Escherichia coli W7 and its consequences on peptidoglycan composition

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12 December 2020

Significance of the methyl group on the oxazine ring of ofloxacin derivatives in the inhibition of bacterial and mammalian type II topoisomerases

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12 December 2020

Escherichia coli parA is an allele of the gyrB gene

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12 December 2020

Quinolone resistance-determining region in the DNA gyrase gyrB gene of Escherichia coli

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12 December 2020

Effects of novel fluoroquinolones on the catalytic activities of eukaryotic topoisomerase II: Influence of the C-8 fluorine group

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12 December 2020

The nucleotide sequence of the fission yeast DNA topoisomerase II gene: structural and functional relationships to other DNA topoisomerases

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12 December 2020

Oxolinic acid, a new synthetic antimicrobial agent. I. In vivtro and in vivo activity

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12 December 2020

Tandem regions of yeast DNA topoisomerase II share homology with different subunits of bacterial gyrase.

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12 December 2020

Preliminary crystallographic analysis of the breakage-reunion domain of the Escherichia coli DNA gyrase A protein

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12 December 2020

Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage.

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12 December 2020

The mode of action of quinolones: The paradox in activity of low and high concentrations and activity in the anaerobic environment

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12 December 2020

Relative beta-lactamase- and transpeptidase-inhibitory activities of the new quinolone WIN-57273 in Staphylococcus aureus

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12 December 2020

A topoisomerase from Escherichia coli related to DNA gyrase

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12 December 2020

Transglycosylase and endopeptidase participate in the degradation of murein during autolysis of Escherichia coli

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12 December 2020

Cloning and characterization of a DNA gyrase A gene from Escherichia coli that confers clinical resistance to 4-quinolones.

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12 December 2020

New topoisomerase essential for chromosome segregation in E. coli.

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12 December 2020

Antitumor quinolones with mammalian topoisomerase II mediated DNA cleavage activity

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12 December 2020

The molecular basis of quinolone action

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12 December 2020

hipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis

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12 December 2020

4-Quinolone resistance mutations in the DNA gyrase of Escherichia coli clinical isolates identified by using the polymerase chain reaction

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12 December 2020

Novel quinolone resistance mutations of the Escherichia coli DNA gyrase A protein: enzymatic analysis of the mutant proteins

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12 December 2020

Inhibitory effects of quinolones on DNA gyrase of Escherichia coli and topoisomerase II of fetal calf thymus

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12 December 2020

Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli

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12 December 2020

Gene organization in the region containing a new gene involved in chromosome partition in Escherichia coli

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12 December 2020

Nalidixic acid-resistant mutations of the gyrB gene of Escherichia coli

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12 December 2020

Isolation and characterization of an Escherichia coli strain exhibiting partial tolerance to quinolones

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12 December 2020

Genetic profile of a nalidixic acid analog: a model for the mechanism of sister chromatid exchange induction

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12 December 2020

Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

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12 December 2020

Susceptibility of Pseudomonas aeruginosa and Escherichia coli biofilms towards ciprofloxacin: effect of specific growth rate

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12 December 2020

Bacterial chromosome segregation: evidence for DNA gyrase involvement in decatenation

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12 December 2020

Probing the limits of the DNA breakage-reunion domain of the Escherichia coli DNA gyrase A protein.

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12 December 2020

Effect of DNA gyrase inhibitors pefloxacin, five other quinolones, novobiocin, and clorobiocin on Escherichia coli topoisomerase I.

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12 December 2020

A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex

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12 December 2020

Use of in vitro topoisomerase II assays for studying quinolone antibacterial agents

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12 December 2020

DNA gyrase and its complexes with DNA: direct observation by electron microscopy

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12 December 2020

Identification of a potent decatenating enzyme from Escherichia coli

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12 December 2020

DNA gyrase-catalyzed decatenation of multiply linked DNA dimers.

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12 December 2020

Mutational resistance to 4-quinolone antibacterial agents

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12 December 2020

Biological role of the pneumococcal amidase. Cloning of the lytA gene in Streptococcus pneumoniae

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12 December 2020

Identifiers

PubMed ID

7689456

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PubMed ID

7689456