(Q40494536)

21 September 2017

title

Roles of PDK-1 and PKN in regulating cell migration and cortical actin formation of PTEN-knockout cells (English)

1 reference

21 September 2017

Mei Ann Lim

1

1 reference

21 September 2017

Linda Yang

2

1 reference

21 September 2017

Yi Zheng

3

1 reference

21 September 2017

Hong Wu

4

1 reference

21 September 2017

Lily Q Dong

5

1 reference

21 September 2017

Feng Liu

6

1 reference

21 September 2017

language of work or name

English

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publication date

1 December 2004

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21 September 2017

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21 September 2017

volume

23

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21 September 2017

issue

58

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21 September 2017

page(s)

9348-9358

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3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

21 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Identification of a putative target for Rho as the serine-threonine kinase protein kinase N

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

1 reference

7 January 2021

Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Rho and Rac take center stage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Identification of PTEN mutations in metastatic melanoma specimens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

PTEN, a unique tumor suppressor gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Advances in Rho-dependent actin regulation and oncogenic transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Akt mediates Rac/Cdc42-regulated cell motility in growth factor-stimulated cells and in invasive PTEN knockout cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Suppression of tumorigenicity and metastasis in B16F10 cells by PTEN/MMAC1/TEP1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Signal-dependent membrane targeting by pleckstrin homology (PH) domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Localization of the PAK1-, WASP-, and IQGAP1-specifying regions of Cdc42.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

The Drosophila Pkn protein kinase is a Rho/Rac effector target required for dorsal closure during embryogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

A novel protein kinase with leucine zipper-like sequences: its catalytic domain is highly homologous to that of protein kinase C

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Activation of PKN, a novel 120-kDa protein kinase with leucine zipper-like sequences, by unsaturated fatty acids and by limited proteolysis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

The PH domain: a common piece in the structural patchwork of signalling proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Hepatocyte growth factor promotes migration of human hepatocellular carcinoma via phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Epidermal growth factor modulates tyrosine phosphorylation of p130Cas. Involvement of phosphatidylinositol 3'-kinase and actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Cloning and expression patterns of two members of a novel protein-kinase-C-related kinase family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Cell migration: Rho GTPases lead the way

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

The role of phosphoinositide 3-kinase lipid products in cell function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Rocks: multifunctional kinases in cell behaviour

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Signaling from Ras to Rac and beyond: not just a matter of GEFs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Phosphatidylinositol 3-kinase and NF-kappaB regulate motility of invasive MDA-MB-231 human breast cancer cells by the secretion of urokinase-type plasminogen activator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Proteolytic activation of PKN by caspase-3 or related protease during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Synthesis and function of 3-phosphorylated inositol lipids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

PI3K/Akt signalling pathway and cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Substrate specificity of alpha(v)beta(3) integrin-mediated cell migration and phosphatidylinositol 3-kinase/AKT pathway activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208147

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208147

1 reference

Dimensions Publication ID

21 September 2017

1043756955

0 references

1 reference