(Q40498087)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15516974%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Lyn deficiency reduces GATA-1, EKLF and STAT5, and induces extramedullary stress erythropoiesis (English)

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4 January 2020

1

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4 January 2020

Mohinder Sarna

4

1 reference

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4 January 2020

author name string

David J McCarthy

2

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4 January 2020

Jessica R Pore

3

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4 January 2020

Aini S Adenan

5

1 reference

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4 January 2020

Michael J Wright

6

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4 January 2020

Wendy Erber

7

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4 January 2020

Peta A Tilbrook

8

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4 January 2020

S Peter Klinken

9

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4 January 2020

language of work or name

English

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publication date

1 January 2005

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4 January 2020

1 reference

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4 January 2020

volume

24

1 reference

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4 January 2020

issue

3

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4 January 2020

page(s)

336-343

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208199

4 January 2020

exact match

0 references

cites work

CrkL is recruited through its SH2 domain to the erythropoietin receptor and plays a role in Lyn-mediated receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

The glucocorticoid receptor is required for stress erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Erythroid Kruppel-like factor (EKLF) coordinates erythroid cell proliferation and hemoglobinization in cell lines derived from EKLF null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

CD45 tyrosine phosphatase inhibits erythroid differentiation of umbilical cord blood CD34+ cells associated with selective inactivation of Lyn.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Transcription factor-mediated lineage switching reveals plasticity in primary committed progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Thyroid hormone receptor-interacting protein 1 modulates cytokine and nuclear hormone signaling in erythroid cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

HS1 interacts with Lyn and is critical for erythropoietin-induced differentiation of erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

STAT5 activation correlates with erythropoietin receptor-mediated erythroid differentiation of an erythroleukemia cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Multiple tyrosine residues in the cytosolic domain of the erythropoietin receptor promote activation of STAT5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

In vitro-derived leukemic erythroid cell lines induced by a raf- and myc-containing retrovirus differentiate in response to erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Src transduces erythropoietin-induced differentiation signals through phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

A "knockdown" mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Src directly tyrosine-phosphorylates STAT5 on its activation site and is involved in erythropoietin-induced signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Jak2 is essential for signaling through a variety of cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

GATA-1-mediated proliferation arrest during erythroid maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Differential regulation of SOCS genes in normal and transformed erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Independent and opposing roles for Btk and lyn in B and myeloid signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Transcription factor erythroid Krüppel-like factor (EKLF) is essential for the erythropoietin-induced hemoglobin production but not for proliferation, viability, or morphological maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Disrupted signaling in a mutant J2E cell line that shows enhanced viability, but does not proliferate or differentiate, with erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Accentuated response to phenylhydrazine and erythropoietin in mice genetically impaired for their GATA-1 expression (GATA-1(low) mice).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

Identification of tyrosine residues within the intracellular domain of the erythropoietin receptor crucial for STAT5 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

7 January 2021

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

7 January 2021

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

7 January 2021

Erythropoietin induces the tyrosine phosphorylation, nuclear translocation, and DNA binding of STAT1 and STAT5 in erythroid cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

7 January 2021

Truncated erythropoietin receptor in a murine erythroleukemia cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208199

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208199

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15516974%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 January 2020

0 references

1 reference