(Q40518043)

English

Death receptor 4 (DR4) efficiently kills breast cancer cells irrespective of their sensitivity to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).

scientific article published on October 2004

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scholarly article

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Europe PubMed Central

21 September 2017

Death receptor 4 (DR4) efficiently kills breast cancer cells irrespective of their sensitivity to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). (English)

1 reference

Europe PubMed Central

21 September 2017

author name string

Irene Kazhdan

1

1 reference

Europe PubMed Central

21 September 2017

Robert A Marciniak

2

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Europe PubMed Central

21 September 2017

publication date

1 October 2004

1 reference

Europe PubMed Central

21 September 2017

Cancer Gene Therapy

1 reference

Europe PubMed Central

21 September 2017

11

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Europe PubMed Central

21 September 2017

10

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Europe PubMed Central

21 September 2017

691-698

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Europe PubMed Central

21 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700747

0 references

Potential and caveats of TRAIL in cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700747

21 January 2018

The potential of TRAIL for cancer chemotherapy

1 reference

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21 January 2018

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) for treatment of prostate cancer: first results and review of the literature

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700747

21 January 2018

Inhibition of NF-kappaB activity enhances TRAIL mediated apoptosis in breast cancer cell lines.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700747

21 January 2018

Apoptosis control by death and decoy receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700747

21 January 2018

Apo2L/TRAIL and its death and decoy receptors

1 reference

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21 January 2018

Mutation analysis and mRNA expression of trail-receptors in human breast cancer.

1 reference

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21 January 2018

Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation.

1 reference

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21 January 2018

Inactivating mutations of KILLER/DR5 gene in gastric cancers

1 reference

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21 January 2018

The short splice form of Casper/c-FLIP is a major cellular inhibitor of TRAIL-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700747

21 January 2018

Selective expression of FLIP in malignant melanocytic skin lesions

1 reference

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21 January 2018

Doxorubicin pretreatment sensitizes prostate cancer cell lines to TRAIL induced apoptosis which correlates with the loss of c-FLIP expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700747

21 January 2018

An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis

1 reference

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21 January 2018

Functional screening of genes suppressing TRAIL-induced apoptosis: distinct inhibitory activities of Bcl-XL and Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700747

21 January 2018

Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700747

21 January 2018

Ectopic expression of Bcl-2 and Bcl-xL inhibits apoptosis induced by TNF-related apoptosis-inducing ligand (TRAIL) through suppression of caspases-8, 7, and 3 and BID cleavage in human acute myelogenous leukemia cell line HL-60.

1 reference

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21 January 2018

Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700747

21 January 2018

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

1 reference

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21 January 2018

Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications

1 reference

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21 January 2018

The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

1 reference

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21 January 2018

Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance

1 reference

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21 January 2018

Identification and characterization of a ligand-independent oligomerization domain in the extracellular region of the CD95 death receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700747

21 January 2018

Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

1 reference

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21 January 2018

A novel telomerase-specific gene therapy: gene transfer of caspase-8 utilizing the human telomerase catalytic subunit gene promoter

1 reference

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21 January 2018

Caspase-8 gene therapy using the human telomerase reverse transcriptase promoter for malignant glioma cells

1 reference

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21 January 2018

Long-term tumor-free survival from treatment with the GFP-TRAIL fusion gene expressed from the hTERT promoter in breast cancer cells.

1 reference

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21 January 2018

Erythroid differentiation sensitizes K562 leukemia cells to TRAIL-induced apoptosis by downregulation of c-FLIP.

1 reference

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21 January 2018

Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells

1 reference

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21 January 2018

Staurosporine-induced death of MCF-7 human breast cancer cells: a distinction between caspase-3-dependent steps of apoptosis and the critical lethal lesions

1 reference

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21 January 2018

Photodynamic therapy-induced death of MCF-7 human breast cancer cells: a role for caspase-3 in the late steps of apoptosis but not for the critical lethal event

1 reference

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21 January 2018

Identification of a caspase 3-independent role of pro-apoptotic factor Bak in TNF-alpha-induced apoptosis

1 reference

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21 January 2018

TRAIL Promotes the Survival and Proliferation of Primary Human Vascular Endothelial Cells by Activating the Akt and ERK Pathways

1 reference

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21 January 2018

Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700747

7 January 2021

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10.1038/SJ.CGT.7700747

1 reference

Europe PubMed Central

21 September 2017

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1 reference

Europe PubMed Central

21 September 2017

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