(Q40522524)

21 September 2017

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title

Activities, localizations, and roles of serine proteases and their inhibitors in human brain tumor progression (English)

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21 September 2017

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M Yamamoto

1

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21 September 2017

R Sawaya

2

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21 September 2017

S Mohanam

3

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21 September 2017

V H Rao

4

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21 September 2017

J M Bruner

5

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21 September 2017

G L Nicolson

6

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21 September 2017

K Ohshima

7

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21 September 2017

J S Rao

8

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21 September 2017

1 January 1994

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Journal of Neuro-Oncology

21 September 2017

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21 September 2017

22

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21 September 2017

2

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21 September 2017

139-151

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Extracellular matrix production and degradation by adenoid cystic carcinoma cells: participation of plasminogen activator and its inhibitor in matrix degradation.

21 September 2017

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12 December 2020

Imbalance of plasminogen activators and their inhibitors in human colorectal neoplasia. Implications of urokinase in colorectal carcinogenesis

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12 December 2020

Plasminogen activators and their inhibitors in a human mammary cell line (HBL-100). Modulation by glucocorticoids

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12 December 2020

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12 December 2020

The plasmin system in human adenocarcinomas and their metastases. A comparative immunofluorescence study

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12 December 2020

Antibodies to plasminogen activator inhibit human tumor metastasis

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12 December 2020

Growth factors in the regulation of pericellular proteolysis: a review

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12 December 2020

Prevention of metastasis by inhibition of the urokinase receptor

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12 December 2020

Cellular localization of type 1 plasminogen activator inhibitor messenger RNA and protein in murine renal tissue

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12 December 2020

Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1.

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12 December 2020

Hormonal regulation of plasminogen activator in rat hepatoma cells

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12 December 2020

Regulation of urokinase-type plasminogen activator expression in squamous-cell carcinoma of the oral cavity

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12 December 2020

Differential protease expression by cutaneous squamous and basal cell carcinomas

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12 December 2020

Inhibitors of urokinase and thrombin in cultured neural cells

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12 December 2020

Plasminogen activator profiles in neoplastic tissues of the human colon

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12 December 2020

Internalization of the urokinase-plasminogen activator inhibitor type-1 complex is mediated by the urokinase receptor

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12 December 2020

Cell-derived proteases and protease inhibitors as regulators of neurite outgrowth

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12 December 2020

Plasminogen activator inhibitor-1 deposition in the extracellular matrix of cultured human mesangial cells

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12 December 2020

Clinical relevance of the urokinase-type and tissue-type plasminogen activators and of their type 1 inhibitor in breast cancer

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12 December 2020

Induction of angiogenesis during the transition from hyperplasia to neoplasia

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12 December 2020

Plasminogen activator inhibitor from human fibrosarcoma cells binds urokinase-type plasminogen activator, but not its proenzyme

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12 December 2020

The plasminogen activator/plasmin system

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12 December 2020

Identification of a protease inhibitor produced by astrocytes that is structurally and functionally homologous to human protease nexin-I.

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12 December 2020

Urokinase and plasminogen activator inhibitor type 1 in pulmonary adenocarcinoma.

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12 December 2020

Degradation of glycoprotein and collagenous components of the basement membrane: studies with urokinase-type plasminogen activator, alpha-thrombin, and plasmin

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12 December 2020

Urokinase-plasminogen activator, a new and independent prognostic marker in breast cancer

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12 December 2020

Detection of an unusually stable fibrinolytic inhibitor produced by bovine endothelial cells

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12 December 2020

Ultrastructural localization of plasma membrane-associated urokinase-type plasminogen activator at focal contacts

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12 December 2020

Plasminogen activator and inhibitor activity in human glioma cells and modulation by sodium butyrate

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12 December 2020

Immunolocalization of urokinase-type plasminogen activator in adenomas and carcinomas of the colorectum.

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12 December 2020

Functional inhibition of endogenously produced urokinase decreases cell proliferation in a human melanoma cell line

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12 December 2020

Urokinase and urokinase receptor: a paracrine/autocrine system regulating cell migration and invasiveness

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12 December 2020

A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins

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12 December 2020

Melanoma-mediated dissolution of extracellular matrix: contribution of urokinase-dependent and metalloproteinase-dependent proteolytic pathways.

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12 December 2020

Conversion of the active to latent plasminogen activator inhibitor from human endothelial cells

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12 December 2020

Suppression of urokinase-type plasminogen activator mRNA levels in human fibrosarcoma cells and synovial fibroblasts by anti-inflammatory glucocorticoids.

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12 December 2020

Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas

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12 December 2020

Mapping of binding sites for heparin, plasminogen activator inhibitor-1, and plasminogen to vitronectin's heparin-binding region reveals a novel vitronectin-dependent feedback mechanism for the control of plasmin formation

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12 December 2020

Inhibition of urokinase-type plasminogen activator by antibodies: the effect on dissemination of a human tumor in the nude mouse

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12 December 2020

Purification of zymogen to plasminogen activator from human glioblastoma cells by affinity chromatography with monoclonal antibody.

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12 December 2020

Secretion of α2-macroglobulin, α2-antiplasmin, and plasminogen activator inhibitor-1 by glioblastoma multiforme in primary organ culture

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12 December 2020

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase

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12 December 2020

The primary plasminogen-activator inhibitors in endothelial cells, platelets, serum, and plasma are immunologically related

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12 December 2020

Postoperative venous thromboembolism and brain tumors: Part II. Hemostatic profile.

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12 December 2020

Computerized tomographic and pathologic studies of the untreated, quiescent, and recurrent glioblastoma multiforme

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12 December 2020

Purification of human protease nexin

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12 December 2020

Vitronectin regulates the synthesis and localization of urokinase-type plasminogen activator in HT-1080 cells

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12 December 2020

Plasminogen activator-plasmin system and neuronal migration.

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12 December 2020

Plasminogen activators and their inhibitors: regulators of extracellular proteolysis and cell function

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12 December 2020

Purification and characterization of a plasminogen activator inhibitor from the histiocytic lymphoma cell line U-937

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12 December 2020

The plasminogen activation system in human colon cancer: messenger RNA for the inhibitor PAI-1 is located in endothelial cells in the tumor stroma

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12 December 2020

Purification and partial characterization of a plasminogen activator inhibitor from the human glioblastoma, U138.

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12 December 2020

In vivo patterns of expression of urokinase and its inhibitor PAI-1 suggest a concerted role in regulating physiological angiogenesis

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12 December 2020

Purification of a specific placental plasminogen activator inhibitor by monoclonal antibody and its complex formation with plasminogen activator

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12 December 2020

Immunohistochemical evidence of urokinase-type plasminogen activator in primary and metastatic tumors of pulmonary adenocarcinoma

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12 December 2020

Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA)

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12 December 2020

Plasminogen activator inhibitor is associated with the extracellular matrix of cultured bovine smooth muscle cells

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12 December 2020

Tumor invasion through the human amniotic membrane: requirement for a proteinase cascade

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12 December 2020

Tissue cooperation in a proteolytic cascade activating human interstitial collagenase

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12 December 2020

In vivo invasion of modified chorioallantoic membrane by tumor cells: the role of cell surface-bound urokinase

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12 December 2020

Plasminogen activator secretion of human tumors in short-term organ culture, including a comparison of primary and metastatic colon tumors

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12 December 2020

Generation in plasma of a fast-acting inhibitor of plasminogen activator in response to endotoxin stimulation

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12 December 2020

Regulation of protease nexin-1 synthesis and secretion in cultured brain cells by injury-related factors

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12 December 2020

Urokinase-type plasminogen activator antigen and early relapse in breast cancer

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12 December 2020

Plasminogen activating enzyme in cultured glioblastoma cells. An immunofluorescence study with monoclonal antibody

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12 December 2020

Transcriptional and posttranscriptional activation of urokinase plasminogen activator gene expression in metastatic tumor cells

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12 December 2020

In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases.

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12 December 2020

Type 1 plasminogen activator inhibitor gene expression following partial hepatectomy

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12 December 2020

Synthesis of urokinase-type plasminogen activator and of type-1 plasminogen activator inhibitor in neuronal cultures of human fetal brain: stimulation by phorbol ester.

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12 December 2020

Facultative polypeptide translocation allows a single mRNA to encode the secreted and cytosolic forms of plasminogen activators inhibitor 2

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12 December 2020

The plasminogen-plasmin system in malignancy

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12 December 2020

Plasminogen activator activity and molecular weight patterns in human brain tumors

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12 December 2020

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

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12 December 2020

Plasminogen activation and regulation of pericellular proteolysis

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12 December 2020

Synthesis and secretion of plasminogen activators and plasminogen activator inhibitors in cell lines of different groups of human lung tumors

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12 December 2020

Localization of urokinase-type plasminogen activator in stromal cells in adenocarcinomas of the colon in humans

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12 December 2020

Possible role of plasminogen activator inhibitor 2 in the prevention of the metastasis of gastric cancer tissues

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12 December 2020

Mechanisms of angiogenesis

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12 December 2020

Modulation of in vitro invasion of human glioblastoma cells by urokinase-type plasminogen activator receptor antibody.

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12 December 2020

Endothelial cells produce a latent inhibitor of plasminogen activators that can be activated by denaturants

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12 December 2020

Regulation of type 1 plasminogen activator inhibitor gene expression in cultured bovine aortic endothelial cells. Induction by transforming growth factor-beta, lipopolysaccharide, and tumor necrosis factor-alpha

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12 December 2020

Modulation of metastatic potential by cell surface urokinase of murine melanoma cells

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12 December 2020

Plasminogen activators, their inhibitors, and urokinase receptor emerge in late stages of melanocytic tumor progression

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12 December 2020

Urokinase-type plasminogen activator is induced in migrating capillary endothelial cells

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12 December 2020

Postoperative changes in the plasmatic levels of tissue-type plasminogen activator and its fast-acting inhibitor--relationship to deep vein thrombosis and influence of prophylaxis

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12 December 2020

Plasminogen Activation by Receptor-Bound Urokinase

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12 December 2020

Elevated levels of urokinase-type plasminogen activator and plasminogen activator inhibitor type-1 in malignant human brain tumors.

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12 December 2020

Examination of urokinase protein/transcript levels and their relationship with laminin degradation in cultured colon carcinoma

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12 December 2020

Bleeding diathesis due to decreased functional activity of type 1 plasminogen activator inhibitor

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12 December 2020

Serpin inhibitors of urokinase and thrombin in normal rat brain and the 9L brain tumor: evidence for elevated expression of protease nexin I-like inhibitor and a novel sodium dodecyl sulfate-activated tumor antithrombin.

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12 December 2020

Role of activated protein C in facilitating basement membrane invasion by tumor cells

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12 December 2020

Regulation of Plasminogen Activator and Plasminogen Activator Inhibitor Expression by Cells of Neural Origin

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12 December 2020

Effects of inhibitors of plasminogen activator, serine proteinases, and collagenase IV on the invasion of basement membranes by metastatic cells.

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12 December 2020

The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes

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12 December 2020

Plasminogen activator release at the neuronal growth cone

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12 December 2020

The human urokinase-plasminogen activator gene and its promoter.

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12 December 2020

Nerve growth factor-gamma activates soluble and receptor-bound single chain urokinase-type plasminogen activator

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12 December 2020

Protease-nexin: A cellular component that links thrombin and plasminogen activator and mediates their binding to cells

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12 December 2020

Enhanced production and extracellular deposition of the endothelial-type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-beta

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12 December 2020

Plasminogen activator inhibitors

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12 December 2020

Inhibition of invasion of HT1080 sarcoma cells expressing recombinant plasminogen activator inhibitor 2.

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12 December 2020

Inhibition of tissue-type plasminogen activator by conditioned medium from cultured human and porcine vascular endothelial cells

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12 December 2020

Latent tissue plasminogen activator produced by human endothelial cells in culture: evidence for an enzyme-inhibitor complex

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12 December 2020

Inhibition of receptor-bound urokinase by plasminogen-activator inhibitors

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12 December 2020

Immunocytochemical localization of urokinase-type plasminogen activator in Lewis lung carcinoma

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12 December 2020

Platelet-derived growth factor and transforming growth factor-beta regulate plasminogen activator inhibitor-1 synthesis in vascular smooth muscle cells

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12 December 2020

Kinetics of the reaction between urokinase and an inhibitor of fibrinolysis from placental tissue

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12 December 2020

The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells

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12 December 2020

Plasminogen activator is a mitogen for astrocytes in developing cerebellum.

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12 December 2020

Plasminogen activator inhibitor-type 1 in Lewis lung carcinoma

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12 December 2020

Growth Factors in the Regulation of Plasminogen-Plasmin System in Tumor Cells

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12 December 2020

Type beta transforming growth factor and epidermal growth factor suppress the plasminogen activator activity in a human glioblastoma cell line

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12 December 2020

Expression of heterogeneous profiles of plasminogen activators and plasminogen activator inhibitors by human glioma lines

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12 December 2020

Inhibition of tumor-cell-mediated extracellular matrix destruction by a fibroblast proteinase inhibitor, protease nexin I

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12 December 2020

A glia-derived neurite-promoting factor with protease inhibitory activity

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12 December 2020

The activation of pro-urokinase by plasma kallikrein and its inactivation by thrombin

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12 December 2020

Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitors

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12 December 2020

Rapid inactivation of the plasminogen-activator inhibitor upon secretion from cultured human endothelial cells

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12 December 2020

Increased PA-inhibitor levels in the postoperative period--no cause-effect relation with increased cortisol

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12 December 2020

Accessibility of receptor-bound urokinase to type-1 plasminogen activator inhibitor

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12 December 2020

Biological significance of tissue plasminogen activator content in brain tumors

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12 December 2020

On the regulation and control of fibrinolysis. Edward Kowalski Memorial Lecture

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12 December 2020

Modulation of plasminogen activator and plasminogen activator inhibitor expression in the human U373 glioblastoma/astrocytoma cell line by inflammatory mediators

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12 December 2020

Reciprocal Modulation of Astrocyte Stellation by Thrombin and Protease Nexin-1

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12 December 2020

The plasminogen-activation system in ovarian tumors

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12 December 2020

Cytokine activation of vascular endothelium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator inhibitor

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12 December 2020

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes

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12 December 2020

Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli

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12 December 2020

Effects of cellular transformation on expression of plasminogen activator inhibitors 1 and 2. Evidence for independent regulation.

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12 December 2020

Plasminogen activator system in human breast cancer

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12 December 2020

Prognostic value of urokinase-type plasminogen activator in 671 primary breast cancer patients

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12 December 2020

Plasminogen activators, tissue degradation, and cancer

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12 December 2020

Extracellular matrix of cultured bovine aortic endothelial cells contains functionally active type 1 plasminogen activator inhibitor

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12 December 2020

Binding of plasminogen activator inhibitor type-1 to extracellular matrix of Hep G2 cells. Evidence that the binding protein is vitronectin

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12 December 2020

Protease nexin-1, an antithrombin with neurite outgrowth activity, is reduced in Alzheimer disease

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12 December 2020

Plasminogen activators (urokinase) mediate neovascularization: possible role in tumor angiogenesis

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12 December 2020

Increase of urokinase-type plasminogen activator gene expression in human lung and breast carcinomas

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12 December 2020

Stimulation of urokinase-type plasminogen activator expression by blockage of E-cadherin-dependent cell-cell adhesion

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12 December 2020

Mammary plasminogen activator: correlation with involution, hormonal modulation and comparison between normal and neoplastic tissue

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12 December 2020

Relationship between cathepsin D, urokinase, and plasminogen activator inhibitors in malignant vs benign breast tumours

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12 December 2020

Localization of plasminogen activators in human colon cancer by immunoperoxidase staining

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12 December 2020

Elevated levels of the rapid inhibitor of plasminogen activator (t-PAI) in acute myocardial infarction

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12 December 2020

Plasminogen-activator inhibitor type 1 is a potent natural inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma cells

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12 December 2020

Directed plasminogen activation at the surface of normal and malignant cells

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12 December 2020

Characterization of the dexamethasone-induced inhibitor of plasminogen activator in HTC hepatoma cells

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12 December 2020

Immunohistochemical localization of plasminogen activator inhibitor type 1 in human brain tumors.

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12 December 2020

Increased levels of plasminogen activator inhibitor-1 (PAI-1) in human brain tumors

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12 December 2020

Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation

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12 December 2020

The majority of type 1 plasminogen activator inhibitor associated with cultured human endothelial cells is located under the cells and is accessible to solution-phase tissue-type plasminogen activator

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12 December 2020

High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis

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12 December 2020

Type-1 plasminogen activator inhibitor in human breast carcinomas

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12 December 2020

10.1016/0923-1137(94)90145-7

Identifiers

DOI

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21 September 2017

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