(Q40528881)

21 September 2017

The kinase activity of fibroblast growth factor receptor 3 with activation loop mutations affects receptor trafficking and signaling (English)

1 reference

21 September 2017

Patricia M-J Lievens

1

1 reference

21 September 2017

Chiara Mutinelli

series ordinal

2

1 reference

21 September 2017

Darcie Baynes

series ordinal

3

1 reference

21 September 2017

Elio Liboi

series ordinal

4

1 reference

21 September 2017

language of work or name

English

0 references

publication date

2 August 2004

1 reference

Journal of Biological Chemistry

21 September 2017

1 reference

21 September 2017

279

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21 September 2017

41

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21 September 2017

43254-43260

1 reference

Signaling--2000 and beyond

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Cell signaling by receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Oncogenic kinase signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Structural basis for FGF receptor dimerization and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Fibroblast growth factor receptor 3 is a negative regulator of bone growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

FGFR activation in skeletal disorders: too much of a good thing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Distinct missense mutations of the FGFR3 lys650 codon modulate receptor kinase activation and the severity of the skeletal dysplasia phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Highly activated Fgfr3 with the K644M mutation causes prolonged survival in severe dwarf mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

The thanatophoric dysplasia type II mutation hampers complete maturation of fibroblast growth factor receptor 3 (FGFR3), which activates signal transducer and activator of transcription 1 (STAT1) from the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

A brefeldin A-like phenotype is induced by the overexpression of a human ERD-2-like protein, ELP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

The transmembrane mutation G380R in fibroblast growth factor receptor 3 uncouples ligand-mediated receptor activation from down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405247200

21 January 2018

Identifiers

DOI

10.1074/JBC.M405247200

1 reference

21 September 2017

1 reference