(Q40535314)

21 September 2017

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title

Molecular cytogenetics of multiple drug resistance (English)

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21 September 2017

main subject

multiple drug resistance

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P V Schoenlein

1

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21 September 2017

publication date

1 January 1993

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21 September 2017

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21 September 2017

volume

12

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21 September 2017

issue

1-3

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21 September 2017

page(s)

63-89

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Cellular and tissue distribution of MRK20 murine monoclonal antibody-defined 85-kDa protein in adriamycin-resistant cancer cell lines.

21 September 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FBF00744658

Structure and expression of the human MDR (P-glycoprotein) gene family

21 January 2018

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12 December 2020

Correlation between long-term survival in breast cancer patients and amplification of two putative oncogene-coamplification units: hst-1/int-2 and c-erbB-2/ear-1

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12 December 2020

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

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12 December 2020

DNA amplification is rare in normal human cells

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12 December 2020

Uptake and retention of daunomycin by mouse leukemic cells as factors in drug response

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12 December 2020

Dominance of colchicine resistance in hybrid CHO cells

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12 December 2020

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

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12 December 2020

Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification

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12 December 2020

An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene

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12 December 2020

Chromosomal destabilization during gene amplification

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12 December 2020

Altered catalytic activity of and DNA cleavage by DNA topoisomerase II from human leukemic cells selected for resistance to VM-26.

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12 December 2020

A 22-kd protein (sorcin/V19) encoded by an amplified gene in multidrug-resistant cells, is homologous to the calcium-binding light chain of calpain

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12 December 2020

Genes amplified and overexpressed in human multidrug-resistant cell lines

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12 December 2020

Model for the formation of double minutes from prematurely condensed chromosomes of replicating micronuclei in drug-treated Chinese hamster ovary cells undergoing DNA amplification.

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12 December 2020

A phosphoglycoprotein associated with taxol resistance in J774.2 cells.

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12 December 2020

Localization of multidrug resistance-associated DNA sequences to human chromosome 7.

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12 December 2020

ATP-dependent bacterial transporters and cystic fibrosis: analogy between channels and transporters

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12 December 2020

Comparison of anthracycline concentrations in S180 cell lines of varying sensitivity

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12 December 2020

Chromosomal localization of three genes coamplified in the multidrug-resistant CHRC5 Chinese hamster ovary cell line

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12 December 2020

Expression of human glutathione S-transferases in Saccharomyces cerevisiae confers resistance to the anticancer drugs adriamycin and chlorambucil

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12 December 2020

The p53 tumour suppressor gene

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12 December 2020

Amplified human MYC oncogenes localized to replicating submicroscopic circular DNA molecules

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12 December 2020

Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines

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12 December 2020

Evidence for linear extrachromosomal elements mediating gene amplification in the multidrug-resistant J774.2 murine cell line

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12 December 2020

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

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12 December 2020

Cloning and characterization of DNA sequences amplified in multidrug-resistant Djungarian hamster and mouse cells.

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12 December 2020

Resistance to actinomycin D and to vincristine induced in a SEWA mouse tumor cell line with concomitant appearance of double minutes and a low molecular weight protein

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12 December 2020

Oncogene amplification in breast cancer

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12 December 2020

Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines

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12 December 2020

The molecular genetics of cancer

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12 December 2020

Localization of the human multiple drug resistance gene, MDR1, to 7q21.1

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12 December 2020

Biological characterization of multidrug-resistant human colon carcinoma sublines induced/selected by two methods

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12 December 2020

Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line

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12 December 2020

Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells

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12 December 2020

Isolation and characterization of DNA sequences amplified in multidrug-resistant hamster cells

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12 December 2020

Expression of a multidrug resistance gene in human cancers

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12 December 2020

Gene amplification in cultured cells

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12 December 2020

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

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12 December 2020

Early dihydrofolate reductase gene amplification events in CHO cells usually occur on the same chromosome arm as the original locus

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12 December 2020

Increased ATP requirement for activity of and complex formation by DNA topoisomerase II from human leukemic CCRF-CEM cells selected for resistance to teniposide

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12 December 2020

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

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12 December 2020

Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells

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12 December 2020

Adriamycin resistance in HL60 cells in the absence of detectable P-glycoprotein

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12 December 2020

Retroviral transfer of a murine cDNA for multidrug resistance confers pleiotropic drug resistance to cells without prior drug selection

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12 December 2020

Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes

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12 December 2020

Biochemistry of multidrug resistance mediated by the multidrug transporter

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12 December 2020

Double minute chromosomes carrying the human multidrug resistance 1 and 2 genes are generated from the dimerization of submicroscopic circular DNAs in colchicine-selected KB carcinoma cells

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12 December 2020

The importance of circular DNA in mammalian gene amplification

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12 December 2020

Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells

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12 December 2020

Drug transport mechanisms in HL60 cells isolated for resistance to adriamycin: evidence for nuclear drug accumulation and redistribution in resistant cells

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12 December 2020

Differential overexpression of three mdr gene family members in multidrug-resistant J774.2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique mdr genes

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12 December 2020

Decreased expression of the amplified mdr1 gene in revertants of multidrug-resistant human myelogenous leukemia K562 occurs without loss of amplified DNA.

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12 December 2020

Altered surface membrane glycoproteins in Vinca alkaloid-resistant human leukemic lymphoblasts

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12 December 2020

Novel submicroscopic extrachromosomal elements containing amplified genes in human cells.

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12 December 2020

Multidrug resistance of DNA-mediated transformants is linked to transfer of the human mdr1 gene

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12 December 2020

Regularities of karyotypic evolution during stepwise amplification of genes determining drug resistance

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12 December 2020

Alteration of plasma membrane glycopeptides and gangliosides of Chinese hamster cells accompanying development of resistance to daunorubicin and vincristine

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12 December 2020

Role of the Glutathione Redox Cycle in Acquired and de Novo Multidrug Resistance

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12 December 2020

A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells

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12 December 2020

Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbrück fluctuation analysis

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12 December 2020

Amplification and expression of genes associated with multidrug resistance in mammalian cells.

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12 December 2020

Expression of hamster P-glycoprotein and multidrug resistance in DNA-mediated transformants of mouse LTA cells

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12 December 2020

Normal diploid human and rodent cells lack a detectable frequency of gene amplification

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12 December 2020

Newly formed chromosome-like structures in independent mouse P388 sublines with developed in vivo mdr1 gene amplification

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12 December 2020

Double minutes arise from circular extrachromosomal DNA intermediates which integrate into chromosomal sites in human HL-60 leukemia cells

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12 December 2020

Expression of phenotypic traits following modulation of colchicine resistance in J774.2 cells

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12 December 2020

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

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12 December 2020

Atypical multiple drug resistance in a human leukemic cell line selected for resistance to teniposide (VM-26).

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12 December 2020

[Nomenclature of the metaphase chromosomes of the djungarian hamster]

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12 December 2020

Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells

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12 December 2020

DNA sequence amplification in mammalian cells.

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12 December 2020

A novel chromosome abnormality in human neuroblastoma and antifolate-resistant Chinese hamster cell lives in culture

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12 December 2020

HT1080/DR4: a P-glycoprotein-negative human fibrosarcoma cell line exhibiting resistance to topoisomerase II-reactive drugs despite the presence of a drug-sensitive topoisomerase II.

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12 December 2020

Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance

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12 December 2020

Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood

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12 December 2020

The chromosomal basis of human neoplasia.

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12 December 2020

Amplicon structure in multidrug-resistant murine cells: a nonrearranged region of genomic DNA corresponding to large circular DNA

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12 December 2020

Localization of the multidrug resistance-associated 170 kDa P-glycoprotein gene to mouse chromosome 5 and to homogeneously staining regions in multidrug-resistant mouse cells by in situ hybridization.

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12 December 2020

Double minute chromosomes and homogeneously staining regions in tumors taken directly from patients versus in human tumor cell lines

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12 December 2020

Combined modalities of resistance in etoposide-resistant human KB cell lines.

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12 December 2020

Cytogenetic and phenotypic analysis of a human colon carcinoma cell line resistant to mitoxantrone

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12 December 2020

Isolation and expression of a complementary DNA that confers multidrug resistance

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12 December 2020

Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and in isolated clones

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12 December 2020

Appearance and detection of multiple copies of the mdr-1 gene in clinical samples of mammary carcinoma.

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12 December 2020

Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells

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12 December 2020

Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells

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12 December 2020

Metaphase chromosome anomaly: association with drug resistance and cell-specific products

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12 December 2020

Gene amplification-associated cytogenetic aberrations and protein changes in vincristine-resistant Chinese hamster, mouse, and human cells

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12 December 2020

In situ hybridization analysis of acquisition and loss of the human multidrug-resistance gene

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12 December 2020

Autonomously replicating episomes contain mdr1 genes in a multidrug-resistant human cell line

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12 December 2020

Mechanism of multidrug resistance

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12 December 2020

Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies

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12 December 2020

Characterization of the human MDR3 P-glycoprotein and its recognition by P-glycoprotein-specific monoclonal antibodies

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12 December 2020

Checkpoints: controls that ensure the order of cell cycle events

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12 December 2020

Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells.

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12 December 2020

High-level, unstable adriamycin resistance in a Chinese hamster mutant cell line with double minute chromosomes.

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12 December 2020

Sorcin (V19), a soluble acidic calcium-binding protein overproduced in multidrug-resistant cells. Identification of the protein by anti-sorcin antibody

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12 December 2020

Correlation of dihydrofolate reductase elevation with gene amplification in a homogeneously staining chromosomal region in L5178Y cells

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12 December 2020

Use of in-gel DNA renaturation for detection and cloning of amplified genes

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12 December 2020

Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies

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12 December 2020

p53: oncogene or anti-oncogene?

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12 December 2020

Differential amplification and disproportionate expression of five genes in three multidrug-resistant Chinese hamster lung cell lines

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12 December 2020

Sequential emergence of distinct resistance phenotypes in murine erythroleukemia cells under adriamycin selection: decreased anthracycline uptake precedes increased P-glycoprotein expression.

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12 December 2020

Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas

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12 December 2020

Pleiotropic phenotype of colchicine-resistant CHO cells: cross-resistance and collateral sensitivity

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12 December 2020

Amplification and overexpression of the P-glycoprotein genes and differential amplification of three other genes in SEWA murine multidrug-resistant cells.

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12 December 2020

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins

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12 December 2020

Isolation and genetic characterization of human KB cell lines resistant to multiple drugs

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12 December 2020

The direct activation of human multidrug resistance gene (MDR1) by anticancer agents

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12 December 2020

ABC Transporters: From Microorganisms to Man

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12 December 2020

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

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12 December 2020

The involvement of a LINE-1 element in a DNA rearrangement upstream of the mdr1a gene in a taxol multidrug-resistant murine cell line

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12 December 2020

Multiply drug-resistant human KB carcinoma cells have decreased amounts of a 75-kDa and a 72-kDa glycoprotein

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12 December 2020

Amplification of DNA sequences in human multidrug-resistant KB carcinoma cells

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12 December 2020

Recent progress in understanding mechanisms of mammalian DNA amplification

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12 December 2020

Continued expression of vinca alkaloid resistance by CCRF-CEM cells after treatment with tunicamycin or pronase.

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12 December 2020

Genetic transfer of non-P-glycoprotein-mediated multidrug resistance (MDR) in somatic cell fusion: dissection of a compound MDR phenotype

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12 December 2020

Cross resistance between vinca alkaloids and anthracyclines in Ehrlich ascites tumor in vivo

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12 December 2020

Cellular resistance to actinomycin D in Chinese hamster cells in vitro: cross-resistance, radioautographic, and cytogenetic studies

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12 December 2020

Pharmacological, molecular, and cytogenetic analysis of "atypical" multidrug-resistant human leukemic cells.

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12 December 2020

Increased synthesis of a low molecular weight protein in vincristine-resistant cells

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12 December 2020

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

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12 December 2020

Reduced permeability in CHO cells as a mechanism of resistance to colchicine

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12 December 2020

Reduced occurrence of mdr-1 amplification in stage-IV breast-cancer patients treated with tamoxifen compared with other endocrine treatments

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12 December 2020

Pharmacological and biological evidence for differing mechanisms of doxorubicin resistance in two human tumor cell lines

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12 December 2020

Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities

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12 December 2020

Glutathione S-transferases and drug resistance

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12 December 2020

Distinctive chromosomal structures are formed very early in the amplification of CAD genes in Syrian hamster cells

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12 December 2020

P-Glycoprotein Expression as a Predictor of the Outcome of Therapy for Neuroblastoma

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12 December 2020

Multidrug resistance in human cancer

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12 December 2020

Verapamil hypersensitivity of vincristine resistant Chinese hamster ovary cell lines.

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12 December 2020

Ability of Circular Extrachromosomal DNA Molecules to Carry Amplified MYCN Protooncogenes in Human Neuroblastomas In Vivo

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12 December 2020

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

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12 December 2020

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

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12 December 2020

The biochemistry of P-glycoprotein-mediated multidrug resistance

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12 December 2020

Action of calcium antagonists on multidrug resistant cells. Specific cytotoxicity independent of increased cancer drug accumulation.

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12 December 2020

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

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12 December 2020

Overexpression and amplification of five genes in a multidrug-resistant Chinese hamster ovary cell line

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12 December 2020

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12 December 2020

Identification of members of the P-glycoprotein multigene family

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12 December 2020

Double minute chromosomes can be produced from precursors derived from a chromosomal deletion

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12 December 2020

Traffic ATPases: a superfamily of transport proteins operating from Escherichia coli to humans

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12 December 2020

Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: prognostic implications.

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12 December 2020

Characterization of adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein

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12 December 2020

Atypical multidrug resistance in CCRF-CEM cells selected for high level methotrexate resistance: reactivity to monoclonal antibody C219 in the absence of P-glycoprotein expression.

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12 December 2020

The human multidrug resistance (mdr1) gene. cDNA cloning and transcription initiation.

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12 December 2020

Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport

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12 December 2020

Detection and mapping of homologous, repeated and amplified DNA sequences by DNA renaturation in agarose gets

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12 December 2020

Cellular resistance to daunomycin in Chinese hamster cells in vitro

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12 December 2020

Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins.

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12 December 2020

Isolation and characterization of an anthracycline-resistant human leukemic cell line.

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12 December 2020

Characterization of an episome produced in hamster cells that amplify a transfected CAD gene at high frequency: functional evidence for a mammalian replication origin

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12 December 2020

Chromosome-mediated gene transfer of multidrug resistance

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12 December 2020

Amino acid substitutions in the sixth transmembrane domain of P-glycoprotein alter multidrug resistance

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12 December 2020

Identifiers

DOI

10.1007/BF00744658

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Dimensions Publication ID

21 September 2017

1034685378

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Fatcat ID

release_qx4pzy2zk5hvzeqfwb74qordku

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Fatcat

https://api.fatcat.wiki/v0/release/qx4pzy2zk5hvzeqfwb74qordku

24 November 2022

mapped directly with Wikidata item

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