(Q40539806)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7771766%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

review article

1 reference

title

Genes for beta-lactam antibiotic biosynthesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7771766%20AND%20SRC:MED&resulttype=core&format=json

Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase precursor

25 October 2019

main subject

0 references

Isopenicillin-N synthase

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Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase, putative

0 references

author

Santiago Gutierrez

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7771766%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

author name string

J F Martín

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7771766%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

publication date

1 January 1995

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7771766%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

number of pages

20

1 reference

inferred from page(s)

published in

Antonie van Leeuwenhoek

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7771766%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

volume

67

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7771766%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7771766%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

page(s)

181-200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7771766%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/bf00871213

25 October 2019

exact match

0 references

cites work

Synthesis of delta-(alpha-aminoadipyl)cysteinylvaline and its role in penicillin biosynthesis

1 reference

https://api.crossref.org/works/10.1007%2FBF00871213

New Findings on Cephalosporin C Biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00871213

Cloning and characterization of the isopenicillin N synthase gene of Streptomyces griseus NRRL 3851 and studies of expression and complementation of the cephamycin pathway in Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00871213

Conversion of isopenicillin N into penicillin N in cell-free extracts of Cephalosporium acremonium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00871213

Cell-free conversion of δ-(l-α-aminoadipyl)-l-cysteinyl-d-valine into an antibiotic with the properties of isopenicillin N in Cephalosporium acremonium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00871213

Biosynthesis of a 7-α-methoxycephalosporin. Incorporation of molecular oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00871213

Purification of isopenicillin N synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00871213

Isopenicillin N synthetase of Penicillium chrysogenum, an enzyme that converts delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine to isopenicillin N.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00871213

Purification and properties of isopenicillin N epimerase from Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00871213

Incorporation of Labeled Precursors into A16886B, a Novel β-Lactam Antibiotic Produced by Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00871213

Purification and characterization of cephalosporin 7α-hydroxylase from Streptomyces clavuligerus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00871213

Purification and characterization of the isopenicillin N epimerase from Nocardia lactamdurans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00871213

The structure of a peptide, containing alpha-aminoadipic acid, cystine and valine, present in the mycelium of Penicillium chrysogenum

21 January 2018

1 reference

12 December 2020

Isolation, sequence determination and expression in Escherichia coli of the isopenicillin N synthetase gene from Cephalosporium acremonium

1 reference

12 December 2020

Evolution by acquisition: the case for horizontal gene transfers

1 reference

12 December 2020

An adenosine triphosphate-dependent carbamoylphosphate-3-hydroxymethylcephem O-carbamoyltransferase from Streptomyces clavuligerus

1 reference

12 December 2020

Resolution of chromosomes III and VI of Aspergillus nidulans by pulsed-field gel electrophoresis shows that the penicillin biosynthetic pathway genes pcbAB, pcbC, and penDE are clustered on chromosome VI (3.0 megabases)

1 reference

12 December 2020

Purification and characterization of the isopenicillin N synthase of Streptomyces lactamdurans

1 reference

12 December 2020

Analysis of the role of cysteine residues in isopenicillin N synthetase activity by site-directed mutagenesis

1 reference

12 December 2020

Purification and initial characterization of an enzyme with deacetoxycephalosporin C synthetase and hydroxylase activities

1 reference

12 December 2020

Expression of the penDE gene of Penicillium chrysogenum encoding isopenicillin N acyltransferase in Cephalosporium acremonium: production of benzylpenicillin by the transformants

1 reference

12 December 2020

The Aspergillus nidulans npeA locus consists of three contiguous genes required for penicillin biosynthesis

1 reference

12 December 2020

Cloning and location of a gene governing lysine epsilon-aminotransferase, an enzyme initiating beta-lactam biosynthesis in Streptomyces spp.

1 reference

12 December 2020

The cluster of penicillin biosynthetic genes. Identification and characterization of the pcbAB gene encoding the alpha-aminoadipyl-cysteinyl-valine synthetase and linkage to the pcbC and penDE genes

1 reference

12 December 2020

Sequence comparison of glyceraldehyde-3-phosphate dehydrogenases from the three urkingdoms: evolutionary implication

1 reference

12 December 2020

Acyl coenzyme A: 6-aminopenicillanic acid acyltransferase from Penicillium chrysogenum and Aspergillus nidulans

1 reference

12 December 2020

Relationships of human protein sequences to those of other organisms

1 reference

12 December 2020

Enzymes involved in penicillin, cephalosporin and cephamycin biosynthesis.

1 reference

12 December 2020

Cloning and expression of the isopenicillin N synthetase gene from Penicillium chrysogenum

1 reference

12 December 2020

Chromosome rearrangements in improved cephalosporin C-producing strains of Acremonium chrysogenum

1 reference

12 December 2020

The cefG gene of Cephalosporium acremonium is linked to the cefEF gene and encodes a deacetylcephalosporin C acetyltransferase closely related to homoserine O-acetyltransferase

1 reference

12 December 2020

The cephamycin biosynthetic genes pcbAB, encoding a large multidomain peptide synthetase, and pcbC of Nocardia lactamdurans are clustered together in an organization different from the same genes in Acremonium chrysogenum and Penicillium chrysogenum

1 reference

12 December 2020

Cyclization of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine to penicillins by cell-free extracts of Streptomyces clavuligerus

1 reference

12 December 2020

Cloning and comparative sequence analysis of the gene coding for isopenicillin N synthase in Streptomyces

1 reference

12 December 2020

Cloning, characterization of the acyl-CoA:6-amino penicillanic acid acyltransferase gene of Aspergillus nidulans and linkage to the isopenicillin N synthase gene

1 reference

12 December 2020

The isopenicillin-N acyltransferase of Penicillium chrysogenum has isopenicillin-N amidohydrolase, 6-aminopenicillanic acid acyltransferase and penicillin amidase activities, all of which are encoded by the single penDE gene

1 reference

12 December 2020

Evolution of isopenicillin N synthase genes may have involved horizontal gene transfer

1 reference

12 December 2020

A gene encoding lysine 6-aminotransferase, which forms the beta-lactam precursor alpha-aminoadipic acid, is located in the cluster of cephamycin biosynthetic genes in Nocardia lactamdurans

1 reference

12 December 2020

Penicillin and cephalosporin biosynthetic genes: structure, organization, regulation, and evolution

1 reference

12 December 2020

Nucleotide sequence of the isopenicillin N synthase gene (pcbC) of the gram negative Flavobacterium sp. SC 12,154.

1 reference

12 December 2020

Cloning, sequence analysis and transcriptional study of the isopenicillin N synthase of Penicillium chrysogenum AS-P-78.

1 reference

12 December 2020

Cell-free conversion of isopenicillin N into deacetoxycephalosporin C by Cephalosporium acremonium mutant M-0198.

1 reference

12 December 2020

Cloning and expression in Escherichia coli of isopenicillin N synthetase genes from Streptomyces lipmanii and Aspergillus nidulans

1 reference

12 December 2020

A pure enzyme catalyzing penicillin biosynthesis

1 reference

12 December 2020

Deacetoxycephalosporin C synthetase and deacetoxycephalosporin C hydroxylase are two separate enzymes in Streptomyces clavuligerus

1 reference

12 December 2020

Purification and partial characterization of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Streptomyces clavuligerus

1 reference

12 December 2020

Sequences of isopenicillin N synthetase genes suggest horizontal gene transfer from prokaryotes to eukaryotes

1 reference

12 December 2020

NMR studies of the active site of isopenicillin N synthase, a non-heme iron(II) enzyme

1 reference

12 December 2020

An electrophoretic molecular karyotype for an industrial strain of Cephalosporium acremonium

1 reference

12 December 2020

1 reference

12 December 2020

Genes for a beta-lactamase, a penicillin-binding protein and a transmembrane protein are clustered with the cephamycin biosynthetic genes in Nocardia lactamdurans

1 reference

12 December 2020

Penicillin acyltransferase in Penicillium chrysogenum

1 reference

12 December 2020

Beta-lactam antibiotic biosynthetic genes have been conserved in clusters in prokaryotes and eukaryotes.

1 reference

12 December 2020

Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from Streptomyces clavuligerus

1 reference

12 December 2020

Characterization and expression in Streptomyces lividans of cefD and cefE genes from Nocardia lactamdurans: the organization of the cephamycin gene cluster differs from that in Streptomyces clavuligerus

1 reference

12 December 2020

Characterization of a loss-of-function mutation in the isopenicillin N synthetase gene of Acremonium chrysogenum

1 reference

12 December 2020

Purification and characterization of a 2-oxoglutarate-linked ATP-independent deacetoxycephalosporin C synthase of Streptomyces lactamdurans

1 reference

12 December 2020

Origin and evolution of organisms as deduced from 5S ribosomal RNA sequences

1 reference

12 December 2020

Localization of the lysine epsilon-aminotransferase (lat) and delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase (pcbAB) genes from Streptomyces clavuligerus and production of lysine epsilon-aminotransferase activity in Escherichia coli

1 reference

12 December 2020

Two genes involved in penicillin biosynthesis are linked in a 5.1 kb SalI fragment in the genome of Penicillium chrysogenum

1 reference

12 December 2020

Factors affecting the isopenicillin N synthetase reaction

1 reference

12 December 2020

Molecular characterization of three loss-of-function mutations in the isopenicillin N-acyltransferase gene (penDE) of Penicillium chrysogenum

1 reference

12 December 2020

Four homologous domains in the primary structure of GrsB are related to domains in a superfamily of adenylate-forming enzymes

1 reference

12 December 2020

Biochemistry and Molecular Genetics of Penicillin Production in Penicillium chrysogenum

1 reference

12 December 2020

Photoaffinity labelling of isopenicillin N synthetase

1 reference

12 December 2020

Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase, the multienzyme integrating the four primary reactions in beta-lactam biosynthesis, as a model peptide synthetase.

1 reference

12 December 2020

Cloning and characterization of the acyl-coenzyme A: 6-aminopenicillanic-acid-acyltransferase gene of Penicillium chrysogenum

1 reference

12 December 2020

Biochemical characterization and molecular genetics of nine mutants of Penicillium chrysogenum impaired in penicillin biosynthesis

1 reference

12 December 2020

1 reference

12 December 2020

Spectroscopic studies of isopenicillin N synthase. A mononuclear nonheme Fe2+ oxidase with metal coordination sites for small molecules and substrate

1 reference

12 December 2020

The beta-lactam biosynthesis genes for isopenicillin N epimerase and deacetoxycephalosporin C synthetase are expressed from a single transcript in Streptomyces clavuligerus

1 reference

12 December 2020

Organization and expression of genes involved in the biosynthesis of antibiotics and other secondary metabolites

1 reference

12 December 2020

Partial purification and characterization of isopenicillin N epimerase activity from Streptomyces clavuligerus

1 reference

12 December 2020

Cloning and sequencing of the beta-lactam hydroxylase gene (cefF) from Streptomyces clavuligerus: gene duplication may have led to separate hydroxylase and expandase activities in the actinomycetes

1 reference

12 December 2020

Copurification and characterization of deacetoxycephalosporin C synthetase/hydroxylase from Cephalosporium acremonium

1 reference

12 December 2020

delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Aspergillus nidulans. The first enzyme in penicillin biosynthesis is a multifunctional peptide synthetase.

1 reference

12 December 2020

IV. Acyl-CoA: 6-APA acyltransferase of Penicillium chrysogenum: studies on substrate specificity using phenylacetyl-CoA variants

1 reference

12 December 2020

Gene disruption of the pcbAB gene encoding ACV synthetase in Cephalosporium acremonium

1 reference

12 December 2020

Production of Streptomyces clavuligerus isopenicillin N synthase in Escherichia coli using two-cistron expression systems

1 reference

12 December 2020

On the production of alpha, beta-heterodimeric acyl-coenzyme A: isopenicillin N-acyltransferase of Penicillium chrysogenum. Studies using a recombinant source.

1 reference

12 December 2020

Partial purification and catalytic properties of a bifunctional enzyme in the biosynthetic pathway of beta-lactams in Cephalosporium acremonium

1 reference

12 December 2020

Direct enzymatic synthesis of natural penicillins using phenylacetyl-CoA: 6-APA phenylacetyl transferase of Penicillium chrysogenum: minimal and maximal side chain length requirements

1 reference

12 December 2020

Cloning and characterization of the isopenicillin N synthetase gene mediating the formation of the beta-lactam ring in Aspergillus nidulans.

1 reference

12 December 2020

Cloning and heterologous expression of the penicillin biosynthetic gene cluster from penicillum chrysogenum

1 reference

12 December 2020

Cloning, characterization, and expression in Escherichia coli of the Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetase

1 reference

12 December 2020

Purification to homogeneity and characterization of acyl coenzyme A:6-aminopenicillanic acid acyltransferase of Penicillium chrysogenum

1 reference

12 December 2020

Deacetoxycephalosporin C hydroxylase of Streptomyces clavuligerus. Purification, characterization, bifunctionality, and evolutionary implication

1 reference

12 December 2020

Enzymatic approach to syntheses of unnatural beta-lactams

1 reference

12 December 2020

The biosynthesis of penicillins and cephalosporins

1 reference

12 December 2020

Molecular cloning of acetyl coenzyme A: deacetylcephalosporin C o-acetyltransferase cDNA from Acremonium chrysogenum: sequence and expression of catalytic activity in yeast

1 reference

12 December 2020

The nucleotide sequences of the 5 S rRNAs of seven molds and a yeast and their use in studying ascomycete phylogeny.

1 reference

12 December 2020

Isolation and partial characterisation of ACV synthetase from Cephalosporium acremonium and Streptomyces clavuligerus

1 reference

12 December 2020

Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Aspergillus nidulans. Molecular characterization of the acvA gene encoding the first enzyme of the penicillin biosynthetic pathway

1 reference

12 December 2020

Resolution of four large chromosomes in penicillin-producing filamentous fungi: the penicillin gene cluster is located on chromosome II (9.6 Mb) in Penicillium notatum and chromosome I (10.4 Mb) in Penicillium chrysogenum.

1 reference

12 December 2020

Cloning, characterization, and expression in Escherichia coli of the Streptomyces clavuligerus gene encoding deacetoxycephalosporin C synthetase.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/JB.171.2.754-760.1989

Identifiers

DOI

10.1007/BF00871213

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7771766%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

1 reference