(Q40542294)

21 September 2017

title

Mapping of the leptin binding sites and design of a leptin antagonist (English)

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21 September 2017

Frank Peelman

1

1 reference

21 September 2017

Katrien Van Beneden

2

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21 September 2017

Lennart Zabeau

3

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21 September 2017

Hannes Iserentant

4

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21 September 2017

Peter Ulrichts

5

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21 September 2017

Delphine Defeau

6

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21 September 2017

Annick Verhee

7

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21 September 2017

Dominiek Catteeuw

8

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21 September 2017

Dirk Elewaut

9

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21 September 2017

Jan Tavernier

10

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21 September 2017

language of work or name

English

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publication date

21 June 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

279

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21 September 2017

issue

39

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21 September 2017

page(s)

41038-41046

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Positional cloning of the mouse obese gene and its human homologue

21 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Biological action of leptin as an angiogenic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Leptin is an autocrine/paracrine regulator of wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Leptin: a pivotal mediator of intestinal inflammation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Leptin-deficient mice are protected from accelerated nephrotoxic nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Leptin signaling deficiency impairs humoral and cellular immune responses and attenuates experimental arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Requirement for leptin in the induction and progression of autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Leptin: linking adipocyte metabolism with cardiovascular and autoimmune diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Leptin, obesity and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Crystal structure of the obese protein leptin-E100

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Mapping the protein universe

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

The ins and outs of leptin receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Functional Analysis of Leptin Receptor Activation Using a Janus Kinase/Signal Transducer and Activator of Transcription Complementation Assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Efficient secretion of biologically active recombinant OB protein (leptin) in Escherichia coli, purification from the periplasm and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

A human leptin mutant induces weight gain in normal mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Structure of an extracellular gp130 cytokine receptor signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Identification of ligand-binding site III on the immunoglobulin-like domain of the granulocyte colony-stimulating factor receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Saturation mutagenesis of the human interleukin 6 receptor-binding site: implications for its three-dimensional structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Identification of ciliary neurotrophic factor (CNTF) residues essential for leukemia inhibitory factor receptor binding and generation of CNTF receptor antagonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

D1 cap region involved in the receptor recognition and neural cell survival activity of human ciliary neurotrophic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Identification of three distinct receptor binding sites of murine interleukin-11

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Receptor recognition by gp130 cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Atomic structure of the GCSF-receptor complex showing a new cytokine-receptor recognition scheme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Subcloning, expression, purification, and characterization of recombinant human leptin-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Leptin receptor (OB-R) oligomerizes with itself but not with its closely related cytokine signal transducer gp130.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Activation of the Leptin Receptor by a Ligand-induced Conformational Change of Constitutive Receptor Dimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Leukemia Inhibitory Factor (LIF), Cardiotrophin-1, and Oncostatin M Share Structural Binding Determinants in the Immunoglobulin-like Domain of LIF Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Molecular mechanisms for viral mimicry of a human cytokine: activation of gp130 by HHV-8 interleukin-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Cloning and characterization of a human leptin receptor using a biologically active leptin immunoadhesin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

Unraveling the multiple roles of leptin in inflammation and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404962200

21 January 2018

Identifiers

DOI

10.1074/JBC.M404962200

1 reference

21 September 2017

1 reference