(Q40545312)

21 September 2017

title

Internalization of exogenously added memapsin 2 (beta-secretase) ectodomain by cells is mediated by amyloid precursor protein (English)

1 reference

21 September 2017

Xiang-Ping Huang

1

1 reference

21 September 2017

Wan-Pin Chang

2

1 reference

21 September 2017

Gerald Koelsch

3

1 reference

21 September 2017

Robert T Turner

4

1 reference

21 September 2017

Florea Lupu

5

1 reference

21 September 2017

Jordan Tang

6

1 reference

21 September 2017

language of work or name

English

0 references

publication date

14 June 2004

1 reference

Journal of Biological Chemistry

21 September 2017

published in

1 reference

21 September 2017

volume

279

1 reference

21 September 2017

issue

36

1 reference

21 September 2017

page(s)

37886-37894

1 reference

Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

21 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Maturation and pro-peptide cleavage of beta-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Crystal structure of memapsin 2 (beta-secretase) in complex with an inhibitor OM00-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Subsite specificity of memapsin 2 (beta-secretase): implications for inhibitor design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Memapsin 2 (beta-secretase) cytosolic domain binds to the VHS domains of GGA1 and GGA2: implications on the endocytosis mechanism of memapsin 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Lipid rafts play an important role in A beta biogenesis by regulating the beta-secretase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Identification of phospholipid scramblase 1 as a novel interacting molecule with beta -secretase (beta -site amyloid precursor protein (APP) cleaving enzyme (BACE))

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Heparan sulfate regulates amyloid precursor protein processing by BACE1, the Alzheimer's beta-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Imaging protein-protein interactions using fluorescence resonance energy transfer microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Fluorescence resonance energy transfer (FRET) microscopy imaging of live cell protein localizations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

The use of FRET imaging microscopy to detect protein-protein interactions and protein conformational changes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Endocytosis and molecular sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

The carboxyl-terminus of BACE contains a sorting signal that regulates BACE trafficking but not the formation of total A(beta).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Signal-dependent trafficking of beta-amyloid precursor protein-transferrin receptor chimeras in madin-darby canine kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Phosphorylation regulates intracellular trafficking of beta-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Sorting of mannose 6-phosphate receptors mediated by the GGAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402130200

21 January 2018

Identifiers

DOI

10.1074/JBC.M402130200

1 reference

21 September 2017

1 reference