(Q40549695)

English

Two conserved cysteine residues are critical for the enzymic function of the human platelet-derived growth factor receptor-beta: evidence for different roles of Cys-822 and Cys-940 in the kinase activity

scientific article published on September 2004

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scholarly article

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Europe PubMed Central

PMC publication ID

21 September 2017

Two conserved cysteine residues are critical for the enzymic function of the human platelet-derived growth factor receptor-beta: evidence for different roles of Cys-822 and Cys-940 in the kinase activity (English)

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

author name string

Joon-Won Lee

1

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Jee-Eun Kim

2

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Eun-Jung Park

3

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Jin-Hyun Kim

4

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Chang-Hun Lee

5

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Seung-Rock Lee

6

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Jongbum Kwon

7

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

language of work or name

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publication date

1 September 2004

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

382

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Pt 2

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

631-639

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

Cysteine residues in the C-terminal lobe of Src: their role in the suppression of the Src kinase

1 reference

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The conformational plasticity of protein kinases

1 reference

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Reversible inactivation of the tumor suppressor PTEN by H2O2

1 reference

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Oxidants painting the cysteine chapel: redox regulation of PTPs

1 reference

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22 September 2017

Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation

1 reference

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22 September 2017

Cell signaling by receptor tyrosine kinases

1 reference

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Protein tyrosine kinase structure and function

1 reference

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Ultraviolet light induces redox reaction-mediated dimerization and superactivation of oncogenic Ret tyrosine kinases

1 reference

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Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2: a key enzyme in angiogenesis

1 reference

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Protein tyrosine phosphatases: mechanisms of catalysis and regulation

1 reference

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Signal transduction via platelet-derived growth factor receptors

1 reference

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Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor

1 reference

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Phosphorylation sites at the C-terminus of the platelet-derived growth factor receptor bind phospholipase C gamma 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133820

22 September 2017

Platelet-derived growth factor receptor signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133820

22 September 2017

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133820

22 September 2017

Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133820

22 September 2017

Requirement for generation of H2O2 for platelet-derived growth factor signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133820

22 September 2017

Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133820

22 September 2017

Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

1 reference

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22 September 2017

Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma

1 reference

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22 September 2017

GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133820

22 September 2017

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133820

22 September 2017

Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1133820

22 September 2017

Clustered cysteine residues in the kinase domain of v-Src: critical role for protein stability, cell transformation and sensitivity to herbimycin A.

1 reference

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25 September 2017

Full activation of the platelet-derived growth factor beta-receptor kinase involves multiple events

1 reference

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17 June 2018

Autoregulatory mechanisms in protein-tyrosine kinases

1 reference

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17 June 2018

Platelet-derived growth factor (PDGF)-induced disulfide-linked dimerization of PDGF receptor in living cells

1 reference

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Characterization of baculovirus-expressed human alpha and beta platelet-derived growth factor receptors

1 reference

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Platelet-derived growth factor-induced H(2)O(2) production requires the activation of phosphatidylinositol 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15175016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conserved cysteine residues are critical for the enzymatic function of the lymphocyte-specific tyrosine protein kinase p56lck

1 reference

https://pubmed.ncbi.nlm.nih.gov/15175016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of sulfhydryl modification reagents on the kinase activity of the epidermal growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15175016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ20040624

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 September 2017

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