(Q40551469)

English

Enhanced efficacy of Escherichia coli nitroreductase/CB1954 prodrug activation gene therapy using an E1B-55K-deleted oncolytic adenovirus vector.

scientific article published on July 2004

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Enhanced efficacy of Escherichia coli nitroreductase/CB1954 prodrug activation gene therapy using an E1B-55K-deleted oncolytic adenovirus vector (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

0 references

Escherichia coli

0 references

oncolytic virus

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Lawrence S Young

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Chen MJ

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Green NK

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Reynolds GM

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Flavell JR

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Mautner V

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Kerr DJ

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Searle PF

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

publication date

1 July 2004

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

11

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Europe PubMed Central

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29 December 2019

14

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1126-1136

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.gt.3302271

0 references

The oncolytic virotherapy treatment platform for cancer: unique biological and biosafety points to consider

1 reference

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21 January 2018

Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

1 reference

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21 January 2018

Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Gene therapy for the treatment of malignant brain tumors with in vivo tumor transduction with the herpes simplex thymidine kinase gene/ganciclovir system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Enzyme/prodrug therapy for head and neck cancer using a catalytically superior cytosine deaminase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Adenoviral vectors capable of replication improve the efficacy of HSVtk/GCV suicide gene therapy of cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy

1 reference

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21 January 2018

Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

The bioactivation of CB 1954 and its use as a prodrug in antibody-directed enzyme prodrug therapy (ADEPT).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Sensitisation of human carcinoma cells to the prodrug CB1954 by adenovirus vector-mediated expression of E. coli nitroreductase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Virus directed enzyme prodrug therapy for ovarian and pancreatic cancer using retrovirally delivered E. coli nitroreductase and CB1954.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Combined adenovirus-mediated nitroreductase gene delivery and CB1954 treatment: a well-tolerated therapy for established solid tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

DNA replication of first-generation adenovirus vectors in tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Efficacy of a replication-competent adenovirus (ONYX-015) following intratumoral injection: intratumoral spread and distribution effects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Genes in the service of therapeutic index: progress for virus-directed enzyme prodrug therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14(ARF) tumor suppressor genes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

The differences in kinetics of rat and human DT diaphorase result in a differential sensitivity of derived cell lines to CB 1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Immune enhancement of nitroreductase-induced cytotoxicity: studies using a bicistronic adenovirus vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Gene delivery from the E3 region of replicating human adenovirus: evaluation of the E3B region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Characterization of 911: a new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Assignment of two human epidermal squamous cell carcinomas cell lines to more than one complementation group for the immortal phenotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Selective extraction of polyoma DNA from infected mouse cell cultures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Neutralisation of adenovirus infectivity by ascitic fluid from ovarian cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

21 January 2018

Expression of Escherichia coli B nitroreductase in established human tumor xenografts in mice results in potent antitumoral and bystander effects upon systemic administration of the prodrug CB1954

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

7 January 2021

based on heuristic

inferred from DOI database lookup

Virus-directed enzyme prodrug therapy: intratumoral administration of a replication-deficient adenovirus encoding nitroreductase to patients with resectable liver cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

7 January 2021

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inferred from DOI database lookup

An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302271

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.GT.3302271

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Dimensions Publication ID

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release_6cactjilxveerpjdhqf2xpnckm

1 reference

https://api.fatcat.wiki/v0/release/6cactjilxveerpjdhqf2xpnckm

24 November 2022

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mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15164095%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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