(Q40559801)

21 September 2017

title

Critical role of residues defining the ligand binding pocket in hepatocyte nuclear factor-4alpha (English)

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21 September 2017

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Eleni Aggelidou

1

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21 September 2017

Panagiota Iordanidou

2

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21 September 2017

Panayota Tsantili

3

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21 September 2017

Georgios Papadopoulos

4

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21 September 2017

Margarita Hadzopoulou-Cladaras

5

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21 September 2017

language of work or name

English

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publication date

30 April 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

279

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21 September 2017

issue

29

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21 September 2017

page(s)

30680-30688

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Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily

21 September 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M401120200

Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

Transactivation of the human apolipoprotein CII promoter by orphan and ligand-dependent nuclear receptors. The regulatory element CIIC is a thyroid hormone response element.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

Distal apolipoprotein C-III regulatory elements F to J act as a general modular enhancer for proximal promoters that contain hormone response elements. Synergism between hepatic nuclear factor-4 molecules bound to the proximal promoter and distal en

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

Transactivation of the ApoCIII promoter by ATF-2 and repression by members of the Jun family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

Mechanism of a transcriptional cross talk between transforming growth factor-beta-regulated Smad3 and Smad4 proteins and orphan nuclear receptor hepatocyte nuclear factor-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M401120200

Functional domains of the nuclear receptor hepatocyte nuclear factor 4.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M401120200

The nuclear receptor ligand-binding domain: structure and function

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M401120200

Analysis of protein dimerization and ligand binding of orphan receptor HNF4alpha

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M401120200

Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

CREB-binding protein is a transcriptional coactivator for hepatocyte nuclear factor-4 and enhances apolipoprotein gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

Protein modelling for all

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M401120200

Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4α

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401120200

21 January 2018

Identifiers

DOI

10.1074/JBC.M401120200

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21 September 2017

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