(Q40560871)

21 September 2017

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title

A critique of the role of the blood-brain barrier in the chemotherapy of human brain tumors (English)

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21 September 2017

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D J Stewart

1

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21 September 2017

publication date

1 January 1994

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Journal of Neuro-Oncology

21 September 2017

published in

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21 September 2017

volume

20

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21 September 2017

issue

2

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21 September 2017

page(s)

121-139

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https://scigraph.springernature.com/pub.10.1007/bf01052723

21 September 2017

exact match

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cites work

Relation of C-6 glial cells in culture to myelin

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https://api.crossref.org/works/10.1007%2FBF01052723

Distribution of tamoxifen and metabolites into brain tissue and brain metastases in breast cancer patients

21 January 2018

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Crossref

https://api.crossref.org/works/10.1007%2FBF01052723

Penetration of 3-deazauridine into human brain, intracerebral tumor, and cerebrospinal fluid

21 January 2018

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12 December 2020

High-dose cyclophosphamide chemotherapy for recurrent CNS tumors in children

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12 December 2020

The effects of mannitol on blood viscosity

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12 December 2020

Natural history of central nervous system acute leukemia in adults

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12 December 2020

A prognostic-factor risk index in advanced non-small-cell lung cancer treated with cisplatin-containing combination chemotherapy

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12 December 2020

Review of selected experimental brain tumor models used in chemotherapy experiments

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12 December 2020

Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy

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12 December 2020

Proceedings: 4'-Demethyl-epipodophyllotoxin-beta-D-thenylidene-glucoside (PTG) in the treatment of malignant intracranial neoplasms

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12 December 2020

Permeability Characteristics of Brain Adjacent to Tumors in Rats

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12 December 2020

A phase II study of cisplatin therapy in recurrent childhood brain tumors. A report from the Childrens Cancer Study Group.

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12 December 2020

Fatty acid composition transport and metabolism in doxorubicin-sensitive and-resistant rat glioblastoma cells.

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12 December 2020

Value of prophylactic cranial irradiation given at complete remission in small cell lung carcinoma

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12 December 2020

Human autopsy-tissue distribution of menogaril and its metabolites.

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12 December 2020

VP-16 in combinations for first-line treatment of malignant germ-cell tumors and gestational choriocarcinoma.

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12 December 2020

Prognostic factors in patients with non-small cell bronchogenic carcinoma and brain metastases

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12 December 2020

Intracerebral penetration and tissue distribution of 2,5-diaziridinyl 3,6-bis(carboethoxyamino) 1,4-benzoquinone (AZQ, NSC-182986).

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12 December 2020

Tumor penetration of AMSA in man

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12 December 2020

Relapse of breast cancer after adjuvant treatment in premenopausal and perimenopausal women: patterns and prognoses

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12 December 2020

Physicochemical considerations and pharmacokinetic behavior in delivery of drugs to the central nervous system.

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12 December 2020

Temporal effects of dexamethasone on blood-to-brain and blood-to-tumor transport of 14C-alpha-aminoisobutyric acid in rat C6 glioma

1 reference

12 December 2020

Quantitative study of microvessel ultrastructure in human peritumoral brain tissue. Evidence for a blood-brain barrier defect.

1 reference

12 December 2020

Human central nervous system and plasma pharmacology of mitoxantrone

1 reference

12 December 2020

Combined intraarterial and systemic chemotherapy for intracerebral tumors

1 reference

12 December 2020

Vascular structures in brain tumors

1 reference

12 December 2020

Pharmacological disposition of N-(phosphonacetyl)-L-aspartate in humans

1 reference

12 December 2020

The role of chemotherapy in the treatment of gliomas in adults

1 reference

12 December 2020

Phase II study of cisplatin in recurrent astrocytomas in adults: A southwest oncology group study

1 reference

12 December 2020

Sex and prognosis in childhood acute lymphoblastic leukaemia

1 reference

12 December 2020

Uptake of labeled dianhydrogalactitol into human gliomas and nervous tissue

1 reference

12 December 2020

CNS metastases in small cell bronchogenic carcinoma.Increasing frequency and changing pattern with lengthening survival

1 reference

12 December 2020

Regional blood flow and capillary permeability in the ethylnitrosourea-induced rat glioma

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12 December 2020

Influence of a continuous high dose infusion of mannitol on cerebral blood flow in normal dogs

1 reference

12 December 2020

Effects of steroids and nonsteroid anti-inflammatory agents on vascular permeability in a rat glioma model.

1 reference

12 December 2020

Quantitative morphology of human glioblastoma multiforme microvessels: structural basis of blood-brain barrier defect.

1 reference

12 December 2020

Distribution of anticancer agents in spontaneous animal tumors. I. Regional blood flow and methotrexate distribution in canine lymphosarcoma

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12 December 2020

Primary central nervous system lymphoma

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12 December 2020

Fatalities during remission of childhood leukemia

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12 December 2020

Combined modality treatment for resected advanced non-small cell lung cancer: local control and local recurrence

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12 December 2020

Central nervous system therapy and combination chemotherapy of childhood lymphocytic leukemia

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12 December 2020

Blood flow and oxygen utilisation in the contralateral cerebral cortex of patients with untreated intracranial tumours as studied by positron emission tomography, with observations on the effect of decompressive surgery

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12 December 2020

Frequency and prognostic importance of pretreatment clinical characteristics in patients with advanced non-small-cell lung cancer treated with combination chemotherapy

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12 December 2020

The distribution of bromine content of dibromodulcitol in the central nervous system of patients with malignant gliomas.

1 reference

12 December 2020

Comparison of symptomatic and prophylactic irradiation of brain metastases from oat cell carcinoma of the lung

1 reference

12 December 2020

Retention of tritiated methotrexate in a transplantable mouse glioma

1 reference

12 December 2020

Uptake and distribution of 3 H-methotrexate by the murine ependymoblastoma

1 reference

12 December 2020

Primary central nervous system lymphoma

1 reference

12 December 2020

Regional blood flow in human tumors

1 reference

12 December 2020

The importance of an isolated central nervous system relapse in children with acute lymphoblastic leukemia

1 reference

12 December 2020

Cyclophosphamide, doxorubicin, vincristine, and dexamethasone in primary lymphoma of the brain: a case report

1 reference

12 December 2020

Treatment of acute lymphoblastic leukaemia: effect of "prophylactic" therapy against central nervous system leukaemia. Report ot the Medical Research Council by the Leukaemia Committee and the Working Party on Leukaemia in Childhood

1 reference

12 December 2020

Management of brain metastases from breast cancer by combination chemotherapy.

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12 December 2020

Early deaths in newly diagnosed cases of pediatric acute leukemia.A southwest oncology group study

1 reference

12 December 2020

Chemotherapy of brain tumors

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12 December 2020

Chiasmatic optic glioma treated with chemotherapy. A preliminary report.

1 reference

12 December 2020

Comparison of drug sensitivity among tumor cells within a tumor, between primary tumor and metastases, and between different metastases in the human tumor colony-forming assay

1 reference

12 December 2020

Pharmacology of methotrexate in the human central nervous system

1 reference

12 December 2020

Platinum Concentrations in Human Autopsy Tumor Samples

1 reference

12 December 2020

Clinical pharmacology of IMPY by radioimmunoassay

1 reference

12 December 2020

Successful treatment of primary central nervous system lymphomas with chemotherapy after osmotic blood-brain barrier opening

1 reference

12 December 2020

Nitrosourea pharmacodynamics in relation to the central nervous system

1 reference

12 December 2020

Evaluation of prognostic factors in chemotherapy of recurrent brain tumors.

1 reference

12 December 2020

Phase II study of procarbazine, CCNU, and vincristine combination chemotherapy in the treatment of malignant brain tumors

1 reference

12 December 2020

Heterogeneity in growth pattern and drug sensitivity of primary tumor and metastases in the human tumor colony-forming assay

1 reference

12 December 2020

Pharmacokinetics of a new water-soluble nitrosourea derivative (ACNU) in human gliomas

1 reference

12 December 2020

Extensive Histological and Cytological Survey of Patients with Acute Leukaemia in "Complete Remission"

1 reference

12 December 2020

Survival with inoperable lung cancer: an integration of prognostic variables based on simple clinical criteria.

1 reference

12 December 2020

Primary chemotherapy of brain metastasis in small-cell lung cancer

1 reference

12 December 2020

Positron emission tomographic measurement of blood-to-brain and blood-to-tumor transport of 82Rb: the effect of dexamethasone and whole-brain radiation therapy.

1 reference

12 December 2020

Concentration of vinblastine in human intracerebral tumor and other tissues.

1 reference

12 December 2020

Chemosensitivity of malignant human brain tumors. Preliminary results.

1 reference

12 December 2020

Hyperosmotic blood-brain barrier disruption in brains of rats with an intracerebrally transplanted RG-C6 tumor.

1 reference

12 December 2020

Penetration of VP-16 (etoposide) into human intracerebral and extracerebral tumors.

1 reference

12 December 2020

Cisplatin plus cytosine arabinoside in adults with malignant gliomas

1 reference

12 December 2020

Prophylactic versus no brain irradiation in regional small cell lung carcinoma.

1 reference

12 December 2020

Human central nervous system distribution of cis-diamminedichloroplatinum and use as a radiosensitizer in malignant brain tumors

1 reference

12 December 2020

Chemotherapy of subcutaneous and intracranial human medulloblastoma xenografts in athymic nude mice

1 reference

12 December 2020

Evaluation of induction of remission, intensification, and central nervous system prophylactic treatment in acute lymphoblastic leukemia

1 reference

12 December 2020

Growth of human lung tumor in the brain of the nude rat as a model to evaluate antitumor agent delivery across the blood-brain barrier.

1 reference

12 December 2020

A pharmacologic basis for brain tumor chemotherapy

1 reference

12 December 2020

Alteration of blood-brain-CSF barrier in experimental meningeal carcinomatosis. A morphologic and adriamycin-penetration study.

1 reference

12 December 2020

cis-Diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells.

1 reference

12 December 2020

Penetration of teniposide (VM-26) into human intracerebral tumors. Preliminary observations on the effect of tumor type, rate of drug infusion and prior treatment with amphotericin B or oral glycerol.

1 reference

12 December 2020

Uptake of tritiated methotrexate by mouse brain tumors after intravenous or intrathecal administration.

1 reference

12 December 2020

Central nervous system (CNS) penetration of homoharringtonine (HHT).

1 reference

12 December 2020

Primary malignant lymphoma of the central nervous system. Results of treatment of 11 cases and review of the literature

1 reference

12 December 2020

Analysis of organ-specific effects on metastatic tumor formation by studies in vitro

1 reference

12 December 2020

Chemotherapy of experimental meningeal carcinomatosis

1 reference

12 December 2020

Systemic Combination Chemotherapy as Primary Treatment of Brain Metastasis From Lung Cancer

1 reference

12 December 2020

Pharmacokinetics and disposition of 3-deazauridine in humans.

1 reference

12 December 2020

Feasibility study of intraarterial vs intravenous cisplatin, BCNU, and teniposide combined with systemic cisplatin, teniposide, cytosine arabinoside, glycerol and mannitol in the treatment of primary and metastatic brain tumors.

1 reference

12 December 2020

Uptake of bleomycin by human brain tumours

1 reference

12 December 2020

Sanctuary therapy: a randomized trial of 724 children with previously untreated acute lymphoblastic leukemia: A Report from Children's Cancer Study Group

1 reference

12 December 2020

A randomized combined modality trial in small cell carcinoma of the lung comparison of combination chemotherapy-radiation therapy versus cyclophosphamide-radiation therapy effects of maintenance chemotherapy and prophylactic whole brain irradiation

1 reference

12 December 2020

Regional blood flow in RT-9 brain tumors.

1 reference

12 December 2020

Metabolism of radioactive cyclophosphamide.Animal tests and clinical studies

1 reference

12 December 2020

Energy-dispersive X-ray fluorescence determination of platinum in plasma, urine, and cerebrospinal fluid of patients administered cis-dichlorodiammineplatinum(II)

1 reference

12 December 2020

Pharmacokinetics of tumor cell exposure to [14C]methotrexate after intracarotid administration without and with hyperosmotic opening of the blood-brain and blood-tumor barriers in rat brain tumors: a quantitative autoradiographic study.

1 reference

12 December 2020

Capillary Ultrastructure and the Blood-Brain Barrier in Human Malignant Brain Tumors

1 reference

12 December 2020

Human tissue distribution of 4'-(9-acridinylamino)-methanesulfon-m-anisidide (NSC 141549, AMSA)

1 reference

12 December 2020

Tamoxifen-induced regression of cerebral metastases in breast carcinoma

1 reference

12 December 2020

Human tissue distribution of platinum after cis-diamminedichloroplatinum

1 reference

12 December 2020

Primary lymphoma of the central nervous system. An unresolved therapeutic problem

1 reference

12 December 2020

Cisplatin neurotoxicity: the relationship between dosage, time, and platinum concentration in neurologic tissues, and morphologic evidence of toxicity

1 reference

12 December 2020

Human autopsy tissue distribution of the epipodophyllotoxins etoposide and teniposide.

1 reference

12 December 2020

Improved survival rate in primary intracranial lymphoma treated by high-dose radiation and systemic vincristine-doxorubicin-cyclophosphamide-prednisolone chemotherapy.

1 reference

12 December 2020

The effect of CNS metastases on the survival of patients with small cell cancer of the lung

1 reference

12 December 2020

Human central nervous system pharmacology of pentamethylmelamine and its metabolites.

1 reference

12 December 2020

Local cerebral blood flow and partition coefficients measured in cerebral astrocytomas of different grades of malignancy

1 reference

12 December 2020

Combination chemotherapy for advanced breast cancer: two regimens containing adriamycin

1 reference

12 December 2020

Determinants of tumor blood flow: a review

1 reference

12 December 2020

The chemotherapy of intracerebral vs subcutaneous murine gliomas. A comparative study of the effect of VM 26.

1 reference

12 December 2020

Brain metastases in breast cancer patients receiving adjuvant chemotherapy

1 reference

12 December 2020

Chemotherapy of brain tumors: physiological and pharmacokinetic considerations

1 reference

12 December 2020

Preliminary report on antitumorigenic activity of cis-dichlorodiamine platinum in metastatic brain tumors

1 reference

12 December 2020

Human autopsy tissue concentrations of mitoxantrone.

1 reference

12 December 2020

[Tracer studies with radioactive-labelled cyclophosphamide in brain tumors].

1 reference

12 December 2020

Penetration of methylglyoxal bis(guanylhydrazone) into intracerebral tumors in humans

1 reference

12 December 2020

Chemotherapy with cisplatin for AFP-secreting germ-cell tumors of the central nervous system

1 reference

12 December 2020

Kinetics of gallium nitrate, a new anticancer agent

1 reference

12 December 2020

Combination Chemotherapy as an Adjuvant Treatment in Operable Breast Cancer

1 reference

12 December 2020

Vascular permeability induced by protein product of malignant brain tumors: inhibition by dexamethasone.

1 reference

12 December 2020

Effect of osmotic blood-brain barrier disruption on methotrexate pharmacokinetics in the dog.

1 reference

12 December 2020

Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults.

1 reference

12 December 2020

Cisplatin and radiation in the treatment of tumors of the central nervous system: pharmacological considerations and results of early studies

1 reference

12 December 2020

Studies with 2,5-piperazinedione, 3,6-bis(5-chloro-2-piperidyl)-,dihydrochloride. III. Biochemical and therapeutic effects in L1210 leukemias sensitive and resistant to alkylating agents: comparison with melphalan, cyclophosphamide, and BCNU

1 reference

12 December 2020

Activity and pharmacokinetics of teniposide in Lewis lung carcinoma-bearing mice.

1 reference

12 December 2020

Chemotherapy of brain metastases: current status

1 reference

12 December 2020

Enhancement of CNS penetration of methotrexate by hyperosmolar intracarotid mannitol or carcinomatous meningitis.

1 reference

12 December 2020

Imidazole carboxamides: relationship of lipophilicity to activity against intracerebral murine glioma 26 and preliminary phase II clinical trial of 5-[3,3-bis(2-chloroethyl)-1-triazeno]imidazole-4-carboxamide (NSC-82196) in primary and secondary bra

1 reference

12 December 2020

Factors in Pathogenesis of Central-nervous-system Leukaemia

1 reference

12 December 2020

Differential distribution of antitumor agents in primary and secondary tumors

1 reference

12 December 2020

Calcium and magnesium dependence of phospholipase A2-catalyzed hydrolysis of phosphatidylcholine small unilamellar vesicles

1 reference

12 December 2020

Biochemically differentiated neoplastic clone of Schwann cells

1 reference

12 December 2020

Platinum concentrations in human glioblastoma multiforme following the use of cisplatin.

1 reference

12 December 2020

A clinical trial of intravenous bleomycin in the treatment of brain tumors

1 reference

12 December 2020

Chemotherapy trials in recurrent primary intracranial germ cell tumors.

1 reference

12 December 2020

Central nervous system pharmacology of Baker's antifolate (NSC139105) in man.

1 reference

12 December 2020

Quantitative contributions of cholesterol and the individual classes of phospholipids and their degree of fatty acyl (un)saturation to membrane fluidity measured by fluorescence polarization.

1 reference

12 December 2020

Prevention of central nervous system leukemia by irradiation

1 reference

12 December 2020

Peak cerebrospinal fluid platinum levels in a patient with ependymoma: evaluation of two different methods of cisplatin administration.

1 reference

12 December 2020

Evaluation of alternating chemotherapy and sites and extent of disease in extensive small cell lung cancer

1 reference

12 December 2020

Quantitative analysis of tight junctions and the uptake of 99mTc in human gliomas.

1 reference

12 December 2020

Treatment of grade III and IV astrocytoma with dimethyl triazeno imidazole carboxamide (DTIC, NSC-45388) alone and in combination with CCNU (NSC-79037) or methyl CCNU (MeCCNU, NSC-95441)

1 reference

12 December 2020

Cytotoxic penetration and concentration in human malignant tumours

1 reference

12 December 2020

Disposition of methylglyoxal bis(guanylhydrazone) (MGBG, NSC-32946) in man

1 reference

12 December 2020

Regional blood flow, capillary permeability, and glucose utilization in two brain tumor models: preliminary observations and pharmacokinetic implications.

1 reference

12 December 2020

INTRATUMORAL VASCULAR CHANGES WITH INCREASED SIZE OF A MAMMARY ADENOCARCINOMA: NEW METHOD AND RESULTS

1 reference

12 December 2020

Comparative permeability of different glioma models to horseradish peroxidase

1 reference

12 December 2020

Duration effective levels of three antitumor drugs in mice with leukemia L1210 implanted intracerebrally and subcutaneously

1 reference

12 December 2020

Effectiveness of the nitrosoureas as a function of their lipid solubility in the chemotherapy of experimental rat brain tumors.

1 reference

12 December 2020

THE PERSISTENCE OF EXTRAMEDULLARY LEUKEMIC INFILTRATES DURING BONE MARROW REMISSION OF ACUTE LEUKEMIA

1 reference

12 December 2020

Combined modality treatment for oat cell carcinoma of the lung: a randomized trial 1,2,3

1 reference

12 December 2020

A prospective randomized phase III trial comparing combination chemotherapy with cyclophosphamide, fluorouracil, and either doxorubicin or epirubicin. French Epirubicin Study Group

1 reference

12 December 2020

Response to vincristine of recurrent brain tumors in children

1 reference

12 December 2020

Response to cytostatic treatment in inoperable adenocarcinoma of the lung: critical implications

1 reference

12 December 2020

Ultrafiltrate and total platinum in plasma and cerebrospinal fluid in a patient with neuroblastoma.

1 reference

12 December 2020

1 reference

12 December 2020

The genetic origin of drug resistance in neoplasms: implications for systemic therapy.

1 reference

12 December 2020

Penetration of N-(phosphonacetyl)-L-aspartate into human central nervous system and intracerebral tumor

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF01052723

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Dimensions Publication ID

21 September 2017

1004305331

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