(Q40568262)

English

Loss of ectodomain shedding due to mutations in the metalloprotease and cysteine-rich/disintegrin domains of the tumor necrosis factor-alpha converting enzyme (TACE).

scientific article published on 9 April 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Loss of ectodomain shedding due to mutations in the metalloprotease and cysteine-rich/disintegrin domains of the tumor necrosis factor-alpha converting enzyme (TACE). (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

author name string

Xiaojin Li

1

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Huizhou Fan

2

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

language of work or name

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publication date

9 April 2004

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

21 September 2017

279

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

26

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

27365-27375

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Remarkable roles of proteolysis on and beyond the cell surface

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Shedding of plasma membrane proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Tobacco Smoke-induced Lung Cell Proliferation Mediated by Tumor Necrosis Factor α-converting Enzyme and Amphiregulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Structure-function relationship and role of tumor necrosis factor-alpha-converting enzyme in the down-regulation of L-selectin by non-steroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Differential Effects of Hydroxamate Inhibitors on PMA- and Ligand-Induced L-Selectin Down-Modulation: Role of Membrane Proximal and Cytoplasmic Domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Tumor necrosis factor-alpha-converting enzyme mediates the inducible cleavage of fractalkine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Phorbol 12-myristate 13-acetate-induced ectodomain shedding and phosphorylation of the human meprinbeta metalloprotease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Functional analysis of the domain structure of tumor necrosis factor-alpha converting enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

TNF-alpha-converting enzyme cleaves the macrophage colony-stimulating factor receptor in macrophages undergoing activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Shedding of interleukin-6 receptor and tumor necrosis factor alpha. Contribution of the stalk sequence to the cleavage pattern of transmembrane proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Chemotactic agents induce IL-6Ralpha shedding from polymorphonuclear cells: involvement of a metalloproteinase of the TNF-alpha-converting enzyme (TACE) type

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Metalloprotease-mediated GH receptor proteolysis and GHBP shedding. Determination of extracellular domain stem region cleavage site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Evidence for a critical role of the tumor necrosis factor alpha convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Tumor necrosis factor-alpha-converting enzyme controls surface expression of c-Kit and survival of embryonic stem cell-derived mast cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Tumor necrosis factor-alpha converting enzyme/ADAM 17 mediates MUC1 shedding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

ADAMs family members as amyloid precursor protein alpha-secretases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

The search for alpha-secretase and its potential as a therapeutic approach to Alzheimer s disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Pulmonary hypoplasia in mice lacking tumor necrosis factor-alpha converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

TACE is required for fetal murine cardiac development and modeling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Highly water-soluble matrix metalloproteinases inhibitors and their effects in a rat adjuvant-induced arthritis model

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Tumour necrosis factor alpha converting enzyme (TACE) activity in the colonic mucosa of patients with inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

TACE is required for the activation of the EGFR by TGF-alpha in tumors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Activated release of membrane-anchored TGF-alpha in the absence of cytosol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Processing of tumor necrosis factor by the membrane-bound TNF-alpha-converting enzyme, but not its truncated soluble form

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Ectodomain shedding of TGF-alpha and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Tumor necrosis factor-alpha converting enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

The shedding of membrane-anchored heparin-binding epidermal-like growth factor is regulated by the Raf/mitogen-activated protein kinase cascade and by cell adhesion and spreading

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Evidence for an interaction of the metalloprotease‒disintegrin tumour necrosis factor α convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease‒disintegrin MDC9 with a novel MAD2-related protein, MAD2β

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme and of an alternatively translated polypeptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Evidence for regulation of the tumor necrosis factor alpha-convertase (TACE) by protein-tyrosine phosphatase PTPH1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Transforming growth factor-alpha and beta-amyloid precursor protein share a secretory mechanism.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Pro-tumor necrosis factor-alpha processing activity is tightly controlled by a component that does not affect notch processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

The tetraspanin CD9 associates with transmembrane TGF-alpha and regulates TGF-alpha-induced EGF receptor activation and cell proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Cysteines 153 and 154 of transmembrane transforming growth factor-alpha are palmitoylated and mediate cytoplasmic protein association

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Mitogen-activated protein kinase-dependent and -independent routes control shedding of transmembrane growth factors through multiple secretases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Transcriptional activation of collagenase-3 by transforming growth factor-beta1 is via MAPK and Smad pathways in human breast cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Specific sequence elements are required for the expression of functional tumor necrosis factor-alpha-converting enzyme (TACE).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Impaired trafficking and activation of tumor necrosis factor-alpha-converting enzyme in cell mutants defective in protein ectodomain shedding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Metalloprotease-dependent protransforming growth factor-alpha ectodomain shedding in the absence of tumor necrosis factor-alpha-converting enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

The canonical methionine 392 of matrix metalloproteinase 2 (gelatinase A) is not required for catalytic efficiency or structural integrity: probing the role of the methionine-turn in the metzincin metalloprotease superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Tailoring tissue inhibitor of metalloproteinases-3 to overcome the weakening effects of the cysteine-rich domains of tumour necrosis factor-alpha converting enzyme.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Inactivating mutations block the tumor necrosis factor-alpha-converting enzyme in the early secretory pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Different transforming growth factor-alpha species are derived from a glycosylated and palmitoylated transmembrane precursor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Role of the Juxtamembrane Domains of the Transforming Growth Factor-α Precursor and the β-Amyloid Precursor Protein in Regulated Ectodomain Shedding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

[29] Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401690200

21 January 2018

Identifiers

10.1074/JBC.M401690200

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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