(Q40569554)

English

Structure-activity relationships in platinum-acridinylthiourea conjugates: effect of the thiourea nonleaving group on drug stability, nucleobase affinity, and in vitro cytotoxicity.

scientific article published on 6 April 2004

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15067524%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Structure-activity relationships in platinum-acridinylthiourea conjugates: effect of the thiourea nonleaving group on drug stability, nucleobase affinity, and in vitro cytotoxicity (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15067524%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

0 references

Sue Berners-Price

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15067524%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

author name string

Margaret C Ackley

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15067524%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Colin G Barry

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15067524%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Amanda M Mounce

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15067524%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Michael C Farmer

4

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26 December 2019

Beth-Erin Springer

5

1 reference

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26 December 2019

Cynthia S Day

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15067524%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Marcus W Wright

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15067524%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Suzanne M Hess

9

1 reference

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26 December 2019

Ulrich Bierbach

10

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26 December 2019

publication date

6 April 2004

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26 December 2019

Journal of Biological Inorganic Chemistry

1 reference

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PubMed publication ID

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26 December 2019

9

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PubMed publication ID

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26 December 2019

4

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26 December 2019

453-461

1 reference

Europe PubMed Central

PubMed publication ID

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26 December 2019

https://scigraph.springernature.com/pub.10.1007/s00775-004-0541-4

0 references

Thermally inert metal ammines as light-inducible DNA-targeted agents. Synthesis, photochemistry, and photobiology of a prototypical rhodium(III)-intercalator conjugate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15067524

12 December 2020

based on heuristic

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Mechanism of action of non-cisplatin type DNA-targeted platinum anticancer agents: DNA interactions of novel acridinylthioureas and their platinum conjugates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15067524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unusual intercalation of acridin-9-ylthiourea into the 5'-GA/TC DNA base step from the minor groove: implications for the covalent DNA adduct profile of a novel platinum-intercalator conjugate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15067524

12 December 2020

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Design, synthesis, and biological activity of a novel non-cisplatin-type platinum-acridine pharmacophore

1 reference

https://pubmed.ncbi.nlm.nih.gov/15067524

12 December 2020

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Structure, Recognition, and Processing of Cisplatin-DNA Adducts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15067524

12 December 2020

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Antitumor activity of 13,14-dihydro-15-deoxy-delta7-prostaglandin-A1-methyl ester integrated into lipid microspheres against human ovarian carcinoma cells resistant to cisplatin in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15067524

12 December 2020

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Unprecedented monofunctional metalation of adenine nucleobase in guanine- and thymine-containing dinucleotide sequences by a cytotoxic platinum-acridine hybrid agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/15067524

12 December 2020

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In vitro studies on the mechanisms of oxaliplatin resistance

1 reference

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12 December 2020

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