(Q40575179)

21 September 2017

Insulin, not leptin, promotes in vitro cell migration to heal monolayer wounds in human corneal epithelium (English)

1 reference

21 September 2017

Lynne J Shanley

1

1 reference

21 September 2017

Colin D McCaig

series ordinal

2

1 reference

21 September 2017

John V Forrester

series ordinal

3

1 reference

21 September 2017

Min Zhao

series ordinal

4

1 reference

21 September 2017

language of work or name

English

0 references

publication date

1 April 2004

1 reference

Investigative Ophthalmology Visual Science

21 September 2017

1 reference

21 September 2017

45

1 reference

21 September 2017

4

1 reference

21 September 2017

1088-1094

1 reference

Systemically and topically supplemented leptin fails to reconstitute a normal angiogenic response during skin repair in diabetic ob/ob mice

21 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Leptin enhances wound re-epithelialization and constitutes a direct function of leptin in skin repair

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Topical insulin in wound healing: a randomised, double-blind, placebo-controlled trial

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Activation of epidermal growth factor receptor during corneal epithelial migration

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Systemically and topically administered leptin both accelerate wound healing in diabetic ob/ob mice

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Leptin, the product of Ob gene, promotes angiogenesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Effects of insulin on wound healing

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Insulin stimulates haptotactic migration of human epidermal keratinocytes through activation of NF-kappa B transcription factor.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Regulation of cell motility by mitogen-activated protein kinase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Positional cloning of the mouse obese gene and its human homologue

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Comparative effects of IGF-I and insulin on the glucose transporter system in rat muscle.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Molecular analysis of signal transduction by growth factors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Signal transmission by the insulin-like growth factors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Wound healing in the patient with diabetes mellitus

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Insulin receptors in cultured mouse retinal cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Cellular and molecular features of lens differentiation: a review of recent advances

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Topical application of insulin in the treatment of decubitus ulcers: a pilot study

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

ERK and p38 MAP kinase pathways are mediators of intestinal epithelial wound-induced signal transduction

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Epidermal growth factor stimulation of phosphatidylinositol 3-kinase during wound closure in rabbit corneal epithelial cells.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

An SV40-immortalized human corneal epithelial cell line and its characterization

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Leptin is an autocrine/paracrine regulator of wound healing

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Insulin receptor at the mouse hepatocyte nucleus after a glucose meal induces dephosphorylation of a 30-kDa transcription factor and a concomitant increase in malic enzyme gene expression

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Effects of insulin on wound healing in diabetic mice

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Actin organization in migrating corneal epithelium of rabbits in situ

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Retinal insulin receptors: localization using a polyclonal anti-insulin receptor antibody

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

The signaling potential of the receptors for insulin and insulin-like growth factor I (IGF-I) in 3T3-L1 adipocytes: comparison of glucose transport activity, induction of oncogene c-fos, glucose transporter mRNA, and DNA-synthesis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Neurotrophic and anhidrotic keratopathy treated with substance P and insulinlike growth factor 1.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Restoration of corneal epithelial barrier function and wound healing by substance P and IGF-1 in rats with capsaicin-induced neurotrophic keratopathy

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Naltrexone, an opioid antagonist, facilitates reepithelialization of the cornea in diabetic rat.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Membrane lipids, EGF receptors, and intracellular signals colocalize and are polarized in epithelial cells moving directionally in a physiological electric field

20 August 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

20 August 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Identification of insulin in the tear film and insulin receptor and IGF-1 receptor on the human ocular surface.

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Substance P, insulinlike growth factor 1, and surface healing.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Involvement of p27(KIP1) degradation by Skp2 in the regulation of proliferation in response to wounding of corneal epithelium.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Migration of human keratinocytes in electric fields requires growth factors and extracellular calcium

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

The mechanism of accelerated corneal epithelial healing by human epidermal growth factor

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459286

Effects of growth factors on corneal wound healing

20 August 2018

1 reference

12 December 2020

Molecular and cellular responses of the corneal epithelium to wound healing

1 reference

12 December 2020

Effect of epidermal growth factor, hepatocyte growth factor, and keratinocyte growth factor, on proliferation, motility and differentiation of human corneal epithelial cells

1 reference

12 December 2020

Stimulatory effects of fibronectin and EGF on migration of corneal epithelial cells

1 reference

12 December 2020

Synergistic effects of substance P with insulin-like growth factor-1 on epithelial migration of the cornea

1 reference

12 December 2020

Mechanisms of recovery from mechanical injury of cultured rat hepatocytes

1 reference

12 December 2020

Insulin receptors in human ocular tissues. Immunohistochemical demonstration in normal and diabetic eyes

1 reference

12 December 2020

Expression of phosphatidylinositol 3-kinase during EGF-stimulated wound repair in rabbit corneal epithelium

1 reference

12 December 2020

Characterization of insulin-like growth factor-1 receptors in rabbit corneal epithelial cells

1 reference

12 December 2020

Corneal structure and sensitivity in type 1 diabetes mellitus

1 reference

12 December 2020

Appearance of leptin in wound fluid as a response to injury

1 reference

12 December 2020

HGF, MAPK, and a small physiological electric field interact during corneal epithelial cell migration

1 reference

12 December 2020

Acceleration of Primary Wound Healing by Insulin

1 reference

12 December 2020

Selective binding of the epidermal growth factor and its specific effects on the epithelial cells of the cornea

1 reference

12 December 2020

Proliferation of corneal epithelium induced by epidermal growth factor

1 reference

12 December 2020

Insulin initiation of lens fiber differentiation in culture: Elongation of embryonic lens epithelial cells

1 reference

12 December 2020

The X, Y, Z hypothesis of corneal epithelial maintenance

1 reference

12 December 2020

Comparison of insulin receptors from bovine retinal blood vessels and nonvascular retinal tissue

1 reference

12 December 2020

Identifiers

DOI

10.1167/IOVS.03-1064

1 reference

21 September 2017

1 reference

21 September 2017

PubMed publication ID

15037573

1 reference