(Q40578220)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7833298%20AND%20SRC:MED&resulttype=core&format=json

26 October 2019

review article

1 reference

title

Quinolinic acid in neurological disease: opportunities for novel drug discovery (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7833298%20AND%20SRC:MED&resulttype=core&format=json

26 October 2019

1 reference

Reinhard JF Jr

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7833298%20AND%20SRC:MED&resulttype=core&format=json

26 October 2019

Erickson JB

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7833298%20AND%20SRC:MED&resulttype=core&format=json

26 October 2019

Flanagan EM

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7833298%20AND%20SRC:MED&resulttype=core&format=json

26 October 2019

publication date

1 January 1994

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7833298%20AND%20SRC:MED&resulttype=core&format=json

26 October 2019

published in

Advances in Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7833298%20AND%20SRC:MED&resulttype=core&format=json

26 October 2019

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7833298%20AND%20SRC:MED&resulttype=core&format=json

26 October 2019

page(s)

85-127

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7833298%20AND%20SRC:MED&resulttype=core&format=json

Major histocompatibility complex antigen expression on rat microglia following epidural kainic acid lesions.

26 October 2019

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An investigation of the mechanisms of delayed neurodegeneration caused by direct injection of quinolinate into the rat striatum in vivo

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7 January 2021

Kynurenine as an Intermediate in the Formation of Nicotinic Acid from Tryptophane by Neurospora

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7 January 2021

Systemic approaches to modifying quinolinic acid striatal lesions in rats

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7 January 2021

Differential sparing of somatostatin-neuropeptide Y and cholinergic neurons following striatal excitotoxin lesions

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7 January 2021

Kynurenine pathway measurements in Huntington's disease striatum: evidence for reduced formation of kynurenic acid

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7 January 2021

Chronic quinolinic acid lesions in rats closely resemble Huntington's disease

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7 January 2021

Delayed demyelination and macrophage invasion: a candidate for secondary cell damage in spinal cord injury

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7 January 2021

3-Hydroxyanthranilic acid metabolism. IV. Spectrophotometric evidence for the formation of an intermediate

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7 January 2021

Quantitative changes in the synaptic vesicle proteins synapsin I and p38 and the astrocyte-specific protein glial fibrillary acidic protein are associated with chemical-induced injury to the rat central nervous system

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7 January 2021

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase.

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7 January 2021

Molecular cloning, sequencing and expression of human interferon-gamma-inducible indoleamine 2,3-dioxygenase cDNA

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7 January 2021

Localization of kynurenine aminotransferase immunoreactivity in the rat hippocampus

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7 January 2021

Cell proliferation after ischemic infarction in gerbil brain

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7 January 2021

Quinolinic acid concentrations in striatal extracellular fluid reach potentially neurotoxic levels following systemic L-tryptophan loading

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7 January 2021

Inhibition of indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase by beta-carboline and indole derivatives

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7 January 2021

A radiometric assay for kynurenine 3-hydroxylase based on the release of 3H2O during hydroxylation of L-[3,5-3H]kynurenine

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7 January 2021

Quinolinic-phosphoribosyl transferase activity is decreased in epileptic human brain tissue

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7 January 2021

On the excitotoxic properties of quinolinic acid, 2,3-piperidine dicarboxylic acids and structurally related compounds

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7 January 2021

Studies on the disposition of quinolinic acid after intracerebral or systemic administration in the rat

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7 January 2021

Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid

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7 January 2021

Quinolinic acid phosphoribosyltransferase in human and rat brain: activity in Huntington's disease and in quinolinate-lesioned rat striatum

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7 January 2021

Quinolinic acid phosphoribosyltransferase in rat brain

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7 January 2021

A radioenzymatic assay for quinolinic acid

1 reference

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7 January 2021

Synthesis of quinolinic acid by 3-hydroxyanthranilic acid oxygenase in rat brain tissue in vitro

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7 January 2021

Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation.

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7 January 2021

Blood?Brain Barrier Transport of Kynurenines: Implications for Brain Synthesis and Metabolism

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7 January 2021

Quinolinate mimics neurotoxic actions of N-methyl-D-aspartate in rat cerebellar slices.

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7 January 2021

The Pyridine Nucleotide Cycle

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7 January 2021

Identification of tryptophan 2,3-dioxygenase RNA in rodent brain.

1 reference

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7 January 2021

Neuroactive kynurenines in Lyme borreliosis

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7 January 2021

Quinolinic acid in culture media used for in vitro neurotoxicology studies

1 reference

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7 January 2021

Metabolism and neuropathologic significance of quinolinic acid and kynurenic acid

1 reference

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7 January 2021

Increased cerebrospinal fluid quinolinic acid, kynurenic acid, and L-kynurenine in acute septicemia

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

(18O)quinolinic acid: its esterification without back exchange for use as internal standard in the quantification of brain and CSF quinolinic acid

1 reference

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7 January 2021

Quantification of quinolinic acid in rat brain, whole blood, and plasma by gas chromatography and negative chemical ionization mass spectrometry: effects of systemic L-tryptophan administration on brain and blood quinolinic acid concentrations

1 reference

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7 January 2021

Delayed increases in regional brain quinolinic acid follow transient ischemia in the gerbil.

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7 January 2021

4-chloro-3-hydroxyanthranilate inhibits brain 3-hydroxyanthranate oxidase.

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7 January 2021

Systemic lipopolysaccharide and pokeweed mitogen increase quinolinic acid content of mouse cerebral cortex

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7 January 2021

Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome

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7 January 2021

Systemic endotoxin increases L-tryptophan, 5-hydroxyindoleacetic acid, 3-hydroxykynurenine and quinolinic acid content of mouse cerebral cortex

1 reference

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7 January 2021

Sustained increases in cerebrospinal fluid quinolinic acid concentrations in rhesus macaques (Macaca mulatta) naturally infected with simian retrovirus type-D.

1 reference

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7 January 2021

Increased ratio of quinolinic acid to kynurenic acid in cerebrospinal fluid of D retrovirus-infected rhesus macaques: relationship to clinical and viral status.

1 reference

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7 January 2021

Brain and plasma quinolinic acid in profound insulin-induced hypoglycemia

1 reference

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7 January 2021

Quinolinic Acid Concentrations in Brain and Cerebrospinal Fluid of Patients with Intractable Complex Partial Seizures

1 reference

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7 January 2021

Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Quinolinic acid concentrations are increased in cerebrospinal fluid of Rhesus macaques (Macaca mulatta) naturally infected with simian retrovirus type-D

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Regional brain and cerebrospinal fluid quinolinic acid concentrations in Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Relationship of neurologic status in macaques infected with the simian immunodeficiency virus to cerebrospinal fluid quinolinic acid and kynurenic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Human macrophages convert L-tryptophan into the neurotoxin quinolinic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

New degradative routes of 5-hydroxytryptophan and serotonin by intestinal tryptophan 2,3-dioxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Determination of serum kynurenine and hepatic tryptophan dioxygenase activity by high-performance liquid chromatography.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Biosynthesis of NAD and nicotinic acid by Clostridium butylicum

1 reference

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7 January 2021

Intravenous administration of L-kynurenine to rhesus monkeys: effect on quinolinate and kynurenate levels in serum and cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Organ distribution of rat kynureninase and changes of its activity during development.

1 reference

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7 January 2021

Quinolinate neurotoxicity in cortical cell culture.

1 reference

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7 January 2021

Quinolinic acid phosphoribosyltransferase: preferential glial localization in the rat brain visualized by immunocytochemistry

1 reference

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7 January 2021

Quinolinic acid metabolism in the rat brain. Immunohistochemical identification of 3-hydroxyanthranilic acid oxygenase and quinolinic acid phosphoribosyltransferase in the hippocampal region

1 reference

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7 January 2021

Glutaric aciduria type 1 an atypical presentation together with some observations upon treatment and the possible cause of cerebral damage

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7 January 2021

Stimulant and convulsive effects of kynurenines injected into brain ventricles in mice

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7 January 2021

Kynurenines and Seizures

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7 January 2021

Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor

1 reference

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7 January 2021

Models of neuronal injury in AIDS: another role for the NMDA receptor?

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7 January 2021

NMDA receptor agonists derived from ibotenic acid. Preparation, neuroexcitation and neurotoxicity

1 reference

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7 January 2021

Deduced primary structure of rat tryptophan-2,3-dioxygenase

1 reference

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7 January 2021

Progressive slowing of reaction time and increasing cerebrospinal fluid concentrations of quinolinic acid in HIV-infected individuals

1 reference

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7 January 2021

The excitotoxin quinolinic acid is present and unevenly distributed in the rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

The excitotoxin quinolinic acid is present in the brain of several mammals and its cortical content increases during the aging process

1 reference

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7 January 2021

Increase in the content of quinolinic acid in cerebrospinal fluid and frontal cortex of patients with hepatic failure

1 reference

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7 January 2021

Content of quinolinic acid and of other tryptophan metabolites increases in brain regions of rats used as experimental models of hepatic encephalopathy

1 reference

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7 January 2021

Modulation of Quinolinic and Kynurenic Acid Content in the Rat Brain: Effects of Endotoxins and Nicotinylalanine

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Abnormally high activity of 3-hydroxyanthranilate 3,4-dioxygenase in brain of epilepsy-prone El mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

High levels of quinolinic acid in brain of epilepsy-prone E1 mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Isolation of L-Kynurenine 3-Hydroxylase from the Mitochondrial Outer Membrane of Rat Liver

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats.

1 reference

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7 January 2021

Neurotypic and gliotypic proteins as biochemical markers of neurotoxicity

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7 January 2021

On the submitochondrial localization of l-kynurenine-3-hydroxylase

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Rat 3-hydroxyanthranilic acid oxygenase: purification from the liver and immunocytochemical localization in the brain

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Cofactor activity of dihydroflavin mononucleotide and tetrahydrobiopterin for murine epididymal indoleamine 2,3-dioxygenase.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Utilization of dihydroflavin mononucleotide and superoxide anion for the decyclization of L-tryptophan by murine epididymal indoleamine 2,3-dioxygenase.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Induction of indoleamine 2,3-dioxygenase: a mechanism of the antitumor activity of interferon gamma

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Exacerbations of multiple sclerosis in patients treated with gamma interferon

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Determination of 3-hydroxykynurenine in human brain and plasma by high-performance liquid chromatography with electrochemical detection

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Brain quinolinic acid in Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Quinolinic acid is a potent lipid peroxidant in rat brain homogenates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Quinolinate in Brain and Cerebrospinal Fluid in Rat Models of Congenital Hyperammonemia

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Cerebral cortex and lung indoleamine-2,3-dioxygenase activity is increased in type-D retrovirus infected macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Chronic effects of γ-interferon on quinolinic acid and indoleamine-2,3-dioxygenase in brain of C57BL6 mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Effects of immune activation on quinolinic acid and neuroactive kynurenines in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-gamma-stimulated monocytes (THP-1 cells).

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Mechanism of delayed increases in kynurenine pathway metabolism in damaged brain regions following transient cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

The role of tryptophan 2,3-dioxygenase in the hormonal control of tryptophan metabolism in isolated rat liver cells. Effects of glucocorticoids and experimental diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Quantification of the importance of individual steps in the control of aromatic amino acid metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Neurotoxicity of quinolinic acid and its derivatives in hypoxic rat hippocampal slices.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

The excitotoxicity of heterocyclic dicar☐yclic acids in rat hippocampal slices: structure-activity relationships

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Differential vulnerability of central neurons of the rat to quinolinic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Quinolinic acid: a pathogen in seizure disorders?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Cerebrospinal fluid levels of quinolinic acid in Huntington's disease and schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Abnormalities of somatosensory evoked potentials in the quinolinic acid model of Huntington's disease: evidence that basal ganglia modulate sensory cortical input

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Brain quinolinic acid in Alzheimer's dementia

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Extensive studies of the heme coordination structure of indoleamine 2,3-dioxygenase and of tryptophan binding with magnetic and natural circular dichroism and electron paramagnetic resonance spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Increased quinolinic acid metabolism following neuronal degeneration in the rat hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Effect of kynurenine loading on quinolinic acid production in the rat: studies in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Production of extracellular quinolinic acid in the striatum studied by microdialysis in unanesthetized rats

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

The effect of pyridoxine deficiency on the metabolism of the aromatic amino acids by isolated rat liver cells.

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https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Quinolinic acid: a potent endogenous excitant at amino acid receptors in CNS

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https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Purification and properties of kynureninase from rat liver

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7 January 2021

The Mechanism of Kynurenine Hydrolysis Catalyzed by Kynureninase

1 reference

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7 January 2021

L-kynurenine aminotransferase and L-α-aminoadipate aminotransferase. I. Evidence for identity

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7 January 2021

Divergent effects of astroglial and microglial secretions on neuron growth and survival

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https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

4-Halo-3-Hydroxyanthranilates are Potent Inhibitors of 3-Hydroxyanthranilate Oxygenase in the Rat Brain in Vitro and in Vivo

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7 January 2021

4-Halo-3-hydroxyanthranilic acids: Potent competitive inhibitors of 3-hydroxy-anthranilic acid oxygenase in vitro

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https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

The calcium channel blocker nifedipine attenuates slow excitatory amino acid neurotoxicity

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https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Extracellular levels of quinolinic acid are moderately increased in rat neostriatum following severe insulin-induced hypoglycaemia

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https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Prolonged exposure to submicromolar concentrations of quinolinic acid causes excitotoxic damage in organotypic cultures of rat corticostriatal system

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7 January 2021

Identification of quinolinic acid in rat and human brain tissue

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https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Neurotoxicity induced by continuous infusion of quinolinic acid into the lateral ventricle in rats.

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https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Effects of vitamin B-6 deficiency and tryptophan loading on urinary excretion of tryptophan metabolites in mammals

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https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

Indoleamine 2,3-dioxygenase

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https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960173-8

7 January 2021

10.1016/S1054-3589(08)60173-8

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