(Q40581037)

21 September 2017

title

Peptidoglycan induces nuclear factor-kappaB activation and cyclooxygenase-2 expression via Ras, Raf-1, and ERK in RAW 264.7 macrophages (English)

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21 September 2017

Bing-Chang Chen

1

1 reference

21 September 2017

Ya-Sheng Chang

2

1 reference

21 September 2017

Ju-Chiun Kang

3

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21 September 2017

Ming-Jen Hsu

4

1 reference

21 September 2017

Joen-Rong Sheu

5

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21 September 2017

Ta-Liang Chen

6

1 reference

21 September 2017

Che-Ming Teng

7

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21 September 2017

Chien-Huang Lin

8

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21 September 2017

language of work or name

English

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publication date

8 March 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

279

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21 September 2017

issue

20

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21 September 2017

page(s)

20889-20897

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Gram-positive organisms and sepsis

21 September 2017

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Micrococci and peptidoglycan activate TLR2-->MyD88-->IRAK-->TRAF-->NIK-->IKK-->NF-kappaB signal transduction pathway that induces transcription of interleukin-8

21 January 2018

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Bacterial peptidoglycan-induced tnf-alpha transcription is mediated through the transcription factors Egr-1, Elk-1, and NF-kappaB.

21 January 2018

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Chemokines are the main proinflammatory mediators in human monocytes activated by Staphylococcus aureus, peptidoglycan, and endotoxin

21 January 2018

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Binding of bacterial peptidoglycan to CD14.

21 January 2018

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21 January 2018

Cyclooxygenases 1 and 2

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Prostaglandin endoperoxide synthase: regulation of enzyme expression

21 January 2018

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Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing

21 January 2018

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Cyclooxygenase-2: regulation and relevance in inflammation

21 January 2018

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Involvement of nuclear factor-kappaB in lipoteichoic acid-induced cyclooxygenase-2 expression in RAW 264.7 macrophages

21 January 2018

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Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase

21 January 2018

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Induction of cyclooxygenase-2 protein by lipoteichoic acid from Staphylococcus aureus in human pulmonary epithelial cells: involvement of a nuclear factor-kappa B-dependent pathway

21 January 2018

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Cyclooxygenase-2--10 years later

21 January 2018

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Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element

21 January 2018

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Transcriptional regulation of cyclooxygenase-2 in mouse skin carcinoma cells. Regulatory role of CCAAT/enhancer-binding proteins in the differential expression of cyclooxygenase-2 in normal and neoplastic tissues

21 January 2018

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Transcriptional regulation of the cyclooxygenase-2 gene in activated mast cells

21 January 2018

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The NF-kappa B and I kappa B proteins: new discoveries and insights

21 January 2018

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

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21 January 2018

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

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Increasing complexity of Ras signaling.

21 January 2018

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Induction of cPLA2 in lung epithelial cells and non-small cell lung cancer is mediated by Sp1 and c-Jun

21 January 2018

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Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3.

21 January 2018

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21 January 2018

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Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1

21 January 2018

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Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

21 January 2018

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Pyrimidinoceptor-mediated potentiation of inducible nitric-oxide synthase induction in J774 macrophages. Role of intracellular calcium.

21 January 2018

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Inducible nitric-oxide synthase is regulated by the proteasome degradation pathway

21 January 2018

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Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans

21 January 2018

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Involvement of Raf-1 in chronic delta-opioid receptor agonist-mediated adenylyl cyclase superactivation

21 January 2018

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Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

21 January 2018

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Phorbol 12-myristate 13-acetate up-regulates the transcription of MUC2 intestinal mucin via Ras, ERK, and NF-kappa B.

21 January 2018

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Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway

21 January 2018

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Function and activation of NF-kappa B in the immune system

21 January 2018

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Expression of mitogen-inducible cyclooxygenase induced by lipopolysaccharide: mediation through both mitogen-activated protein kinase and NF-kappaB signaling pathways in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311279200

Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase

21 January 2018

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Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms.

21 January 2018

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A diarylheptanoid from lesser galangal (Alpinia officinarum) inhibits proinflammatory mediators via inhibition of mitogen-activated protein kinase, p44/42, and transcription factor nuclear factor-kappa B.

21 January 2018

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NF-kappaB activation mediates the response of a subpopulation of basal uroepithelial cells to a cell wall component of Enterococcus faecalis

21 January 2018

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Role of the IkappaB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat liver epithelial cells

21 January 2018

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The Toll/interleukin-1 receptor domain: a molecular switch for inflammation and host defence

21 January 2018

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21 January 2018

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21 January 2018

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Myeloid differentiation factor 88-dependent post-transcriptional regulation of cyclooxygenase-2 expression by CpG DNA: tumor necrosis factor-alpha receptor-associated factor 6, a diverging point in the Toll-like receptor 9-signaling

21 January 2018

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Ras participates in the activation of p38 MAPK by interleukin-1 by associating with IRAK, IRAK2, TRAF6, and TAK-1

21 January 2018

1 reference

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v-src induction of the TIS10/PGS2 prostaglandin synthase gene is mediated by an ATF/CRE transcription response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311279200

Lipoteichoic acid-induced cyclooxygenase-2 expression requires activations of p44/42 and p38 mitogen-activated protein kinase signal pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311279200

Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311279200

Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311279200

Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311279200

Transcriptional activation of the cyclooxygenase-2 gene in endotoxin-treated RAW 264.7 macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311279200

Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311279200

I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311279200

Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311279200

Divergent roles for Ras and Rap in the activation of p38 mitogen-activated protein kinase by interleukin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311279200

21 January 2018

Identifiers

DOI

10.1074/JBC.M311279200

1 reference

21 September 2017

1 reference