(Q40585576)

21 September 2017

title

Modulation of beta-catenin phosphorylation/degradation by cyclin-dependent kinase 2. (English)

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21 September 2017

Chun Shik Park

1

1 reference

21 September 2017

Sung Il Kim

2

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21 September 2017

Mi Su Lee

3

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21 September 2017

Cho-Ya Youn

4

1 reference

21 September 2017

Dae Joong Kim

5

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21 September 2017

Eek-Hoon Jho

6

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21 September 2017

Woo Keun Song

7

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21 September 2017

language of work or name

English

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publication date

25 February 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

279

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21 September 2017

issue

19

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21 September 2017

page(s)

19592-19599

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Cadherins, catenins and APC protein: interplay between cytoskeletal complexes and signaling pathways.

21 September 2017

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The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

21 January 2018

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Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

21 January 2018

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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

21 January 2018

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

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Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription

21 January 2018

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Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin.

21 January 2018

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Roles of Axin in the Wnt signalling pathway

21 January 2018

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

21 January 2018

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beta-catenin is a target for the ubiquitin-proteasome pathway

21 January 2018

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The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

21 January 2018

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An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

21 January 2018

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The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

21 January 2018

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The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

21 January 2018

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beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation

21 January 2018

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Biological activity of soluble wingless protein in cultured Drosophila imaginal disc cells

21 January 2018

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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

21 January 2018

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Functional interaction of beta-catenin with the transcription factor LEF-1

21 January 2018

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Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

21 January 2018

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Identification of c-MYC as a target of the APC pathway

21 January 2018

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

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Expression cloning of oncogenes by retroviral transfer of cDNA libraries

21 January 2018

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The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 January 2018

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Beta-catenin regulation during the cell cycle: implications in G2/M and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Exogenous expression of beta-catenin regulates contact inhibition, anchorage-independent growth, anoikis, and radiation-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Cyclin-dependent kinases: engines, clocks, and microprocessors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Specific regulation of E2F family members by cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Regulation of the ubiquitin-conjugating enzyme hHR6A by CDK-mediated phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Wnt signaling stabilizes the dual-function protein beta-catenin in diverse cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Cyclin a-CDK phosphorylation regulates MDM2 protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

An artificial cell-cycle inhibitor isolated from a combinatorial library

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Targeting cyclin-dependent kinases in Drosophila with peptide aptamers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Stabilization of beta-catenin by genetic defects in melanoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Targets of cyclin-dependent protein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

In vivo and in vitro phosphorylation at Ser-493 in the glutamate (E)-segment of neurofilament-H subunit by glycogen synthase kinase 3beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Cyclin dependent kinase regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Cyclin-dependent kinase control of centrosome duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Specific phosphorylation of nucleophosmin on Thr(199) by cyclin-dependent kinase 2-cyclin E and its role in centrosome duplication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Cyclin A- and cyclin E-Cdk complexes shuttle between the nucleus and the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

The ubiquitin-proteasome pathway and serine kinase activity modulate adenomatous polyposis coli protein-mediated regulation of beta-catenin-lymphocyte enhancer-binding factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

Phosphorylation of tau protein by recombinant GSK-3beta: pronounced phosphorylation at select Ser/Thr-Pro motifs but no phosphorylation at Ser262 in the repeat domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M314208200

21 January 2018

Identifiers

DOI

10.1074/JBC.M314208200

1 reference

21 September 2017

1 reference