(Q40589859)

21 September 2017

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title

Pharmacokinetic contributions to postantibiotic effects. Focus on aminoglycosides (English)

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21 September 2017

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G G Zhanel

1

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PubMed ID

7851055

21 September 2017

W A Craig

series ordinal

2

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21 September 2017

1 November 1994

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Clinical Pharmacokinetics

21 September 2017

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21 September 2017

27

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21 September 2017

5

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21 September 2017

377-392

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https://scigraph.springernature.com/pub.10.2165/00003088-199427050-00005

21 September 2017

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Comparative kinetics and efficacy of amikacin administered once or twice daily in the treatment of systemic gram-negative infections.

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12 December 2020

Once versus thrice daily gentamicin in patients with serious infections

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12 December 2020

Postantibiotic effect of CI-960, enoxacin and ciprofloxacin on Escherichia coli: effect on morphology and haemolysin activity

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12 December 2020

Isoniazid uptake and growth inhibition of Mycobacterium tuberculosis in relation to time and concentration of pulsed drug exposures

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12 December 2020

Growth kinetics of respiratory pathogens after short exposures to ampicillin and erythromycin in vitro

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12 December 2020

Penicillin-aminoglycoside synergy and post-antibiotic effect for enterococci

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12 December 2020

Effects of benzylpenicillin on Streptococcus pyogenes during the postantibiotic phase in vitro

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12 December 2020

Influence of dosage schedule on renal cortical accumulation of amikacin and tobramycin in man

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12 December 2020

The post-antibiotic effect of teicoplanin: monotherapy and combination studies

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12 December 2020

Platelet microbicidal protein enhances antibiotic-induced killing of and postantibiotic effect in Staphylococcus aureus

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12 December 2020

Practicalities of once-daily aminoglycoside dosing

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12 December 2020

Enhancement of the in vitro and in vivo activities of clarithromycin against Haemophilus influenzae by 14-hydroxy-clarithromycin, its major metabolite in humans

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12 December 2020

Postantibiotic suppression of bacterial growth

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12 December 2020

Lomefloxacin-induced modification of the kinetics of growth of gram-negative bacteria and susceptibility to phagocytic killing by human neutrophils.

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12 December 2020

Postantibiotic effect of penicillin plus gentamicin versus Enterococcus faecalis in vitro and in vivo

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12 December 2020

Effect of pooled human cerebrospinal fluid on the postantibiotic effects of cefotaxime, ciprofloxacin, and gentamicin against Escherichia coli

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12 December 2020

Impact of the dosage schedule on the efficacy of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats

1 reference

12 December 2020

The rate of bactericidal action of penicillin in vitro as a function of its concentration, and its paradoxically reduced activity at high concentrations against certain organisms

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12 December 2020

The postantifungal effect of 5-fluorocytosine on Candida albicans

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12 December 2020

Does administration of an aminoglycoside in a single daily dose affect its efficacy and toxicity?

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12 December 2020

Efficacy of different dosing schedules of tobramycin for treating a murine Klebsiella pneumoniae bronchopneumonia

1 reference

12 December 2020

Antibiotic therapy of infections due to Pseudomonas aeruginosa in normal and granulocytopenic mice: comparison of murine and human pharmacokinetics

1 reference

12 December 2020

Postantibiotic effect of amikacin and rifapentine against Mycobacterium avium complex

1 reference

12 December 2020

The bactericidal action of penicillin in vivo: the participation of the host, and the slow recovery of the surviving organisms

1 reference

12 December 2020

The postantibiotic effect

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12 December 2020

Prospective randomized study of once-daily versus thrice-daily netilmicin regimens in patients with intraabdominal infections

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12 December 2020

[Post-antibiotic effect of ciprofloxacin alone and in combination on Streptococcus faecalis]

1 reference

12 December 2020

In vitro antimicrobial activity and postantibiotic effect of lomefloxacin, a new difluoroquinolone.

1 reference

12 December 2020

Kinetics of antimicrobial activity

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12 December 2020

In vitro assessment of the postantibiotic effect of lomefloxacin against gram-positive and gram-negative pathogens

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12 December 2020

Correlation of pharmacokinetic parameters to efficacy of antibiotics: relationships between serum concentrations, MIC values, and bacterial eradication in patients with gram-negative pneumonia.

1 reference

12 December 2020

A prospective randomized study comparing once- versus twice-daily amikacin dosing in critically ill adult and paediatric patients

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12 December 2020

Pharmacodynamics of daptomycin and vancomycin on Enterococcus faecalis and Staphylococcus aureus demonstrated by studies of initial killing and postantibiotic effect and influence of Ca2+ and albumin on these drugs

1 reference

12 December 2020

Antimicrobial activity of subinhibitory concentrations of aminoglycosides against Pseudomonas aeruginosa as determined by the killing-curve method and the postantibiotic effect

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12 December 2020

Constant infusions vs. intermittent doses of gentamicin against Pseudomonas aeruginosa in vitro

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12 December 2020

The importance of pharmacodynamics in determining the dosing interval in therapy for experimental pseudomonas endocarditis in the rat

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12 December 2020

The post-antibiotic effect

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12 December 2020

Antimicrobial Activity of Subinhibitory Concentrations of Ciprofloxacin against <i>Pseudomonas aeruginosa </i>as Determined by the Killing Curve Method and the Postantibiotic Effect

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12 December 2020

Postantibiotic effect of aminoglycosides on gram-negative bacteria evaluated by a new method

1 reference

12 December 2020

A multicentric study of netilmicin once daily versus thrice daily in patients with appendicitis and other intra-abdominal infections

1 reference

12 December 2020

Recommendations for the calculation of the post-antibiotic effect for beta-lactams and gram-negative bacilli

1 reference

12 December 2020

Quantitation of postantibiotic effect by measuring CO2 generation of bacteria with the BACTEC blood culture system

1 reference

12 December 2020

Pharmacodynamic effects of subinhibitory concentrations of beta-lactam antibiotics in vitro

1 reference

12 December 2020

Bactericidal Activity of Cephalosporins in an In Vitro Model Simulating Serum Levels

1 reference

12 December 2020

Influence of human urine on the in vitro activity and postantibiotic effect of ciprofloxacin against Escherichia coli

1 reference

12 December 2020

Once daily aminoglycoside dosing: maintained efficacy with reduced nephrotoxicity?

1 reference

12 December 2020

Efficacy and safety of once daily versus intermittent dosing of tobramycin in rabbits with acute pyelonephritis

1 reference

12 December 2020

Killing and regrowth of bacteria in vitro: a review.

1 reference

12 December 2020

Postantibiotic effect in Pseudomonas aeruginosa following single and multiple aminoglycoside exposures in vitro

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12 December 2020

Mode of interaction between beta-lactam antibiotics and the exocellular DD-carboxypeptidase--transpeptidase from Streptomyces R39

1 reference

12 December 2020

The postantibiotic effect induced by antimicrobial combinations.

1 reference

12 December 2020

Comparative trial of single-dose versus twice-daily sisomicin in bacteriuric patients

1 reference

12 December 2020

In vitro activity of sparfloxacin (CI-978; AT-4140) for clinical Legionella isolates, pharmacokinetics in guinea pigs, and use to treat guinea pigs with L. pneumophila pneumonia

1 reference

12 December 2020

Synergy between penicillin and gentamicin against enterococci

1 reference

12 December 2020

Impact of the antibiotic dosage schedule on efficacy in experimental lung infections.

1 reference

12 December 2020

Postantibiotic effect of imipenem on gram-positive and gram-negative micro-organisms

1 reference

12 December 2020

Once-daily dosing regimen for aminoglycoside plus beta-lactam combination therapy of serious bacterial infections: comparative trial with netilmicin plus ceftriaxone

1 reference

12 December 2020

Correlation between pharmacokinetics, pharmacodynamics and efficacy of antibacterial agents in animal models

1 reference

12 December 2020

THE RECOVERY OF BACTERIA FROM THE TOXIC EFFECTS OF PENICILLIN.

1 reference

12 December 2020

Synergic post-antibiotic effect of mecillinam, in combination with other beta-lactam antibiotics in relation to morphology and initial killing

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12 December 2020

Single, large, daily dosing versus intermittent dosing of tobramycin for treating experimental pseudomonas pneumonia

1 reference

12 December 2020

Synergistic post-antibiotic effect of amikacin and beta-lactam antibiotics on Enterococcus faecalis

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12 December 2020

Once-daily aminoglycoside therapy

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12 December 2020

Chemoprophylactic efficacy against experimental endocarditis caused by beta-lactamase-producing, aminoglycoside-resistant enterococci is associated with prolonged serum inhibitory activity

1 reference

12 December 2020

Once-daily vs. continuous aminoglycoside dosing: efficacy and toxicity in animal and clinical studies of gentamicin, netilmicin, and tobramycin

1 reference

12 December 2020

Daily single-dose gentamicin therapy in experimental pyelonephritis

1 reference

12 December 2020

Netilmicin in the treatment of gram-negative bacteremia: single daily versus multiple daily dosage

1 reference

12 December 2020

Comparative postantibacterial activities of pefloxacin, ciprofloxacin, and ofloxacin against intracellular multiplication of Legionella pneumophila serogroup 1

1 reference

12 December 2020

Pharmacodynamics of amikacin in vitro and in mouse thigh and lung infections

1 reference

12 December 2020

Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal model

1 reference

12 December 2020

The influence of tobramycin dosage regimens on nephrotoxicity, ototoxicity, and antibacterial efficacy in a rat model of subcutaneous abscess

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12 December 2020

Postantibiotic sub-MIC effects of vancomycin, roxithromycin, sparfloxacin, and amikacin

1 reference

12 December 2020

Postantibiotic and bactericidal effect of imipenem against Pseudomonas aeruginosa

1 reference

12 December 2020

Synergistic effect of ampicillin or vancomycin in combination with decreasing concentrations of streptomycin against enterococci

1 reference

12 December 2020

Postantibiotic Effect of Ciprofloxacin Compared with that of Five Other Quinolones

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12 December 2020

Postantibiotic leukocyte enhancement: increased susceptibility of bacteria pretreated with antibiotics to activity of leukocytes

1 reference

12 December 2020

Impact of the antibiotic dosage schedule on efficacy in experimental soft tissue infections

1 reference

12 December 2020

[Experimental study of optimal dose interval in antibiotic therapy]

1 reference

12 December 2020

Comparison of two methods for determining in vitro postantibiotic effects of three antibiotics on Escherichia coli

1 reference

12 December 2020

New In Vitro Model to Study the Effect of Antibiotic Concentration and Rate of Elimination on Antibacterial Activity

1 reference

12 December 2020

Human pharmacodynamics of beta-lactams, aminoglycosides and their combination

1 reference

12 December 2020

Once daily administration of netilmicin compared with thrice daily, both in combination with metronidazole, in gangrenous and perforated appendicitis

1 reference

12 December 2020

The postantibiotic effect of amikacin alone and in combination with piperacillin on gram-negative bacteria

1 reference

12 December 2020

Comparative killing activity and postantibiotic effect of streptomycin combined with ampicillin, ciprofloxacin, imipenem, piperacillin or vancomycin against strains of Streptococcus faecalis and Streptococcus faecium.

1 reference

12 December 2020

Nephrotoxicity of gentamicin and tobramycin given once daily or continuously in dogs

1 reference

12 December 2020

Postantibiotic effect of beta-lactam antibiotics on Escherichia coli evaluated by bioluminescence assay of bacterial ATP.

1 reference

12 December 2020

Sub-inhibitory and post-antibiotic effects of spiramycin and erythromycin on Staphylococcus aureus.

1 reference

12 December 2020

Use of the Malthus Microbial Growth Analyser to study the post antibiotic effect of antibiotics

1 reference

12 December 2020

The Recovery Period following Exposure of Bacteria to Penicillins

1 reference

12 December 2020

In vitro postantibiotic effect of daptomycin (LY146032) against Enterococcus faecalis and methicillin-susceptible and methicillin-resistant Staphylococcus aureus strains

1 reference

12 December 2020

Post-antibiotic suppressive effect of ciprofloxacin against gram-positive and gram-negative bacteria.

1 reference

12 December 2020

Postantibiotic effects

1 reference

12 December 2020

Comparative antibiotic dose-effect relations at several dosing intervals in murine pneumonitis and thigh-infection models

1 reference

12 December 2020

Absence of a postantibiotic effect in experimental Pseudomonas endocarditis treated with imipenem, with or without gentamicin.

1 reference

12 December 2020

Postantibiotic effects of imipenem, norfloxacin, and amikacin in vitro and in vivo

1 reference

12 December 2020

A study of amikacin given once versus twice daily in serious infections

1 reference

12 December 2020

Persistent effect of antibiotics on Staphylococcus aureus after exposure for limited periods of time

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12 December 2020

Human serum enhances the postantibiotic effect of fluoroquinolones against Staphylococcus aureus

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12 December 2020

Theory and applications of pulse dosing: a summary of the symposium

1 reference

12 December 2020

Studies on the postantibiotic effect and the postantibiotic sub-MIC effect of meropenem.

1 reference

12 December 2020

The Influence of Dosage Regimen on Experimental Gentamicin Nephrotoxicity: Dissociation of Peak Serum Levels from Renal Failure

1 reference

12 December 2020

The action of penicillin on Staphylococcus

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12 December 2020

Postantibiotic effect of imipenem on Pseudomonas aeruginosa

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12 December 2020

Impact of pH and cationic supplementation on in vitro postantibiotic effect

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12 December 2020

The Action of Penicillin on Staphylococcus: Further Observations on the Effect of a Short Exposure

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12 December 2020

Single-dose daily gentamicin therapy in urinary tract infection

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12 December 2020

Factors affecting duration of in-vivo postantibiotic effect for aminoglycosides against gram-negative bacilli

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12 December 2020

Once-daily versus thrice-daily administration of netilmicin in combination therapy of Pseudomonas aeruginosa infection in a man-adapted neutropenic animal model

1 reference

12 December 2020

Effect of cephalothin on growth patterns of micro-organisms

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12 December 2020

The postantibiotic suppressive effect of L-ofloxacin, an optically active isomer of ofloxacin.

1 reference

12 December 2020

Continuous infusion of beta-lactam antibiotics

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12 December 2020

The postantibiotic effect: a review of in vitro and in vivo data

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12 December 2020

Determinants of efficacy and toxicity of aminoglycosides

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12 December 2020

Postantibiotic effect of roxithromycin, erythromycin, and clindamycin against selected gram-positive bacteria and Haemophilus influenzae

1 reference

12 December 2020

What is the evidence for once-daily aminoglycoside therapy?

1 reference

12 December 2020

In-vitro postantibiotic effects of miocamycin and erythromycin on gram-positive cocci

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12 December 2020

Pharmacodynamics of beta-lactam antibiotics on gram-negative bacteria: initial killing, morphology and postantibiotic effect

1 reference

12 December 2020

In vitro activity of dactimicin, a novel pseudodisaccharide aminoglycoside, compared with activities of other aminoglycosides

1 reference

12 December 2020

10.2165/00003088-199427050-00005

Identifiers

DOI

1 reference

PubMed ID

7851055

Dimensions Publication ID

21 September 2017

0 references

1 reference

PubMed ID

7851055