(Q40596779)

21 September 2017

Caffeine inhibits homology-directed repair of I-SceI-induced DNA double-strand breaks (English)

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21 September 2017

Huichen Wang

1

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21 September 2017

Wilfried Boecker

2

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21 September 2017

Hongyan Wang

3

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21 September 2017

Xiang Wang

4

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21 September 2017

Jun Guan

5

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21 September 2017

Larry H Thompson

6

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21 September 2017

Jac A Nickoloff

7

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21 September 2017

George Iliakis

8

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21 September 2017

language of work or name

English

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publication date

1 January 2004

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21 September 2017

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21 September 2017

23

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21 September 2017

824-834

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21 September 2017

3

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207168

21 September 2017

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cites work

Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Growth and death of HeLa cells in the presence of caffeine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

The action of caffeine on X-irradiated HeLa cells. VI. Damping of the structured age-survival function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

The action of caffeine on X-irradiated HeLa cells. VII. Evidence that caffeine enhances expression of potentially lethal radiation damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

The action of caffeine on X-irradiated HeLa cells. VIII. Recovery from potentially lethal damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Reducing the radiation-induced G2 delay causes HeLa cells to undergo apoptosis instead of mitotic death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Spontaneous and ultraviolet light-induced direct repeat recombination in mammalian cells frequently results in repeat deletion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Caffeine inhibits the checkpoint kinase ATM

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

XRCC3 controls the fidelity of homologous recombination: roles for XRCC3 in late stages of recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

XRCC3 is required for efficient repair of chromosome breaks by homologous recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

The action of caffeine on X-irradiated HeLa cells. II. Synergistic lethality

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Loss of S-phase-dependent radioresistance in irs-1 cells exposed to X-rays

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Effects of caffeine on ultraviolet-irradiated mouse L cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Induction, repair and biological relevance of radiation-induced DNA lesions in eukaryotic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

The potentiation by caffeine of X-ray damage to cultured human skin fibroblasts from normal subjects and ataxia-telangiectasia patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Sequestration of mammalian Rad51-recombination protein into micronuclei

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

A case of caffeine-mediated cancellation of mitotic delay without enhanced breakage in V79 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

The role of DNA double strand breaks in lonizing radiation-induced killing of eukaryotic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Effects of caffeine on X-irradiated synchronous, asynchronous and plateau phase mouse ascites cells: the importance of progression through the cell cycle for caffeine enhancement of killing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Evidence that repair and expression of potentially lethal damage cause the variations in cell survival after X irradiation observed through the cell cycle in Ehrlich ascites tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Chromosome breaks and genomic instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Effects of caffeine on protein phosphorylation and cell cycle progression in X-irradiated two-cell mouse embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Mechanism by which caffeine potentiates lethality of nitrogen mustard

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Identification and purification of two distinct complexes containing the five RAD51 paralogs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Cell cycle regulation in response to DNA damage in mammalian cells: a historical perspective

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Effects of methylated xanthines on mammalian cells treated with bifunctional alkylating agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Override of the radiation-induced mitotic block in human tumour cells by methylxanthines and its relationship to the potentiation of cytotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Effect of caffeine on DNA synthesis in irradiated and unirradiated mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Modulation of radiation-induced apoptosis and G2/M block in murine T-lymphoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Characterization of two DNA double-stranded break repair-deficient cell lines that express inactive DNA-dependent protein kinase catalytic subunits

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Caffeine-increased radiosensitivity is not dependent on a loss of G2/M arrest or apoptosis in bladder cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Pathways of DNA double-strand break repair during the mammalian cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

An ionizing radiation-sensitive mutant of CHO cells: irs-20. I. Isolation and initial characterization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Chromosomal double-strand breaks induce gene conversion at high frequency in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

The XRCC2 DNA repair gene: identification of a positional candidate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Rad51 accumulation at sites of DNA damage and in postreplicative chromatin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Differential post-irradiation caffeine response in normal diploid versus SV40-transformed human fibroblasts: potential role of nuclear organization and protein-composition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

1 reference

7 January 2021

The action of caffeine on X-irradiated HeLa cells. IV. Progression delays and enhanced cell killing at high caffeine concentrations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

The action of caffeine on X-irradiated HeLa cells. I. Delayed inhibition of DNA synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

INTERACTION OF NUCLEIC ACIDS, I. PHYSICAL BINDING OF THYMINE, ADENINE, STEROIDS, AND AROMATIC HYDROCARBONS TO NUCLEIC ACIDS

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Variation in sensitizing effect of caffeine in human tumour cell lines after gamma-irradiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Caffeine Enhancement of X-Ray Killing in Cultured Human and Rodent Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Effects of caffeine on radiation-induced phenomena associated with cell-cycle traverse of mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Caffeine could not efficiently sensitize homologous recombination repair-deficient cells to ionizing radiation-induced killing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Caffeine-induced radiosensitization is independent of nonhomologous end joining of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Selective radiosensitization of p53-deficient cells by caffeine-mediated activation of p34cdc2 kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207168

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207168

1 reference

Dimensions Publication ID

21 September 2017

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1 reference