(Q40597996)

21 September 2017

Signaling through JAK2-STAT5 pathway is essential for IL-3-induced activation of microglia (English)

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21 September 2017

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Chandramohan Natarajan

1

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21 September 2017

Subramaniam Sriram

2

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21 September 2017

Gladson Muthian

3

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21 September 2017

John J Bright

4

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21 September 2017

1 January 2004

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21 September 2017

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21 September 2017

45

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21 September 2017

188-196

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21 September 2017

2

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Inflammatory mechanisms in Alzheimer's disease: implications for therapy

21 September 2017

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

C10 is a novel chemokine expressed in experimental inflammatory demyelinating disorders that promotes recruitment of macrophages to the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

Transcriptional analysis of multiple sclerosis brain lesions reveals a complex pattern of cytokine expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

Possible participation of a JAK2 signaling pathway in recombinant rat interleukin-5-induced prolongation of rat eosinophil survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

IFN-gamma regulation of class II transactivator promoter IV in macrophages and microglia: involvement of the suppressors of cytokine signaling-1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

Indictment of the microglia as the villain in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain

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https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Expression of interleukin-3 and tumor necrosis factor-beta mRNAs in cultured microglia

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https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Cytokines: coordinators of immune and inflammatory responses

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https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Rac is activated by erythropoietin or interleukin-3 and is involved in activation of the Erk signaling pathway

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https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Interleukin-3 signals through multiple isoforms of Stat5.

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https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Functionally distinct isoforms of STAT5 are generated by protein processing

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https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligand

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Cytotoxicity of microglia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Microglia is a component of the prion protein amyloid plaque in the Gerstmann-Sträussler-Scheinker syndrome.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

The microglial cell. A historical review

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

CD40 engagement stimulates IL-12 p70 production by human microglial cells: basis for Th1 polarization in the CNS

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Animal models of demyelination.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Expression of IL-12 in CNS and lymphoid organs of mice with experimental allergic encephalitis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Mechanisms of immune injury in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Macrophage/microglial-mediated primary demyelination and motor disease induced by the central nervous system production of interleukin-3 in transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Targeted CNS expression of interferon-gamma in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Microglia: Intrinsic immuneffector cell of the brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Microglia as mediators of inflammatory and degenerative diseases

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Function and signal transduction mediated by the interleukin 3 receptor system in hematopoiesis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Microglia are the major cell type expressing MHC class II in human white matter.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Tumor necrosis factor identified in multiple sclerosis brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Primary demyelination in transgenic mice expressing interferon-gamma

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Cytokine modulation of murine microglial cell superoxide production

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Induction of MHC class II antigen expression on murine microglia by interleukin-3

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Regional hypomyelination and dysplasia in transgenic mice with astrocyte-directed expression of interferon-gamma.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Tyrosine kinase inhibition: an approach to drug development

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Common subunits of cytokine receptors and the functional redundancy of cytokines

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 transduce signals through two forms of STAT5.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Critical influences of the cytokine orchestration on the outcome of myelin antigen-specific T-cell autoimmunity in experimental autoimmune encephalomyelitis and multiple sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Astrocyte-targeted expression of IL-12 induces active cellular immune responses in the central nervous system and modulates experimental allergic encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Clinical trials of interferons in multiple sclerosis. What have we learned?

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Crystalloid inclusions in brain macrophages and hemopoietic tissue in GFAP-IL3 mice resemble inclusions identified in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Association between Tumor Necrosis Factor-α and Disease Progression in Patients with Multiple Sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Molecular biology of microglia cytokine and chemokine receptors and microglial activation.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Increased severity of experimental autoimmune encephalomyelitis, chronic macrophage/microglial reactivity, and demyelination in transgenic mice producing tumor necrosis factor-alpha in the central nervous system

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Ras-dependent activation of c-Jun N-terminal kinase/stress-activated protein kinase in response to interleukin-3 stimulation in hematopoietic BaF3 cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Brain macrophages: evaluation of microglia and their functions

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Phenotypic differences between human monocytes/macrophages and microglial cells studied in situ and in vitro

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Mouse microglial cell lines differing in constitutive and interferon-gamma-inducible antigen-presenting activities for naive and memory CD4+ and CD8+ T cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Separate precursor cells for macrophages and microglia in mouse brain: immunophenotypic and immunoregulatory properties of the progeny.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Differential activation of microglia after experimental spinal cord injury.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Specific tropism of HIV-1 for microglial cells in primary human brain cultures.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Immunocytochemical characterisation of the immune reaction in the central nervous system in multiple sclerosis. Possible role for microglia in lesion growth.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Janus kinase 2 is involved in stromal cell-derived factor-1alpha-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.10316

7 January 2021

Identifiers

DOI

10.1002/GLIA.10316

1 reference

21 September 2017

1 reference