(Q40598895)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

title

RhoA/ROCK signaling suppresses hypertrophic chondrocyte differentiation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

main subject

hypertrophic chondrocyte

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

author name string

Guoyan Wang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Anita Woods

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Shalev Sabari

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Luca Pagnotta

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Lee-Anne Stanton

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

language of work or name

English

0 references

publication date

15 January 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

17 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

volume

279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

issue

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

page(s)

13205-13214

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Developmental regulation of the growth plate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Type X collagen, a product of hypertrophic chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

In situ hybridization studies on the expression of type X collagen in fetal human cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Collagenase-3 (MMP-13) and integral membrane protein 2a (Itm2a) are marker genes of chondrogenic/osteoblastic cells in bone formation: sequential temporal, and spatial expression of Itm2a, alkaline phosphatase, MMP-13, and osteocalcin in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

The fate of the terminally differentiated chondrocyte: evidence for microenvironmental regulation of chondrocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

The genetic basis for skeletal diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

A recurrent mutation in the tyrosine kinase domain of fibroblast growth factor receptor 3 causes hypochondroplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Distinct mutations in the receptor tyrosine kinase gene ROR2 cause brachydactyly type B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Mutation of the gene encoding the ROR2 tyrosine kinase causes autosomal recessive Robinow syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Regulatory mechanisms in the pathways of cartilage and bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Regulation of cell function by Rho family GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Rho GTPases and their effector proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Rho family proteins: coordinating cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Regulation and functions of Rho-associated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Rocks: multifunctional kinases in cell behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Analysis of thymocyte development reveals that the GTPase RhoA is a positive regulator of T cell receptor responses in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

The role of RhoA in tissue polarity and Frizzled signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Cell type-specific roles for Cdc42, Rac, and RhoL in Drosophila oogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Localization of silencer and enhancer elements in the human type X collagen gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Use of a new rat chondrosarcoma cell line to delineate a 119-base pair chondrocyte-specific enhancer element and to define active promoter segments in the mouse pro-alpha 1(II) collagen gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Identification of the cyclin D1 gene as a target of activating transcription factor 2 in chondrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

p38 MAP kinase signalling is required for hypertrophic chondrocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Multipotency of a bone marrow stromal cell line, TBR31-2, established from ts-SV40 T antigen gene transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Role of Runx genes in chondrocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

TGFbeta and PTHrP control chondrocyte proliferation by activating cyclin D1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Molecular cloning and characterization of CDEP, a novel human protein containing the ezrin-like domain of the band 4.1 superfamily and the Dbl homology domain of Rho guanine nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Effectors for the Rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Integrin-linked kinase regulates chondrocyte shape and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Dihydrocytochalasin B enhances transforming growth factor-beta-induced reexpression of the differentiated chondrocyte phenotype without stimulation of collagen synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Modulation and reexpression of the chondrocyte phenotype; mediation by cell shape and microfilament modification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Cell cycle genes in chondrocyte proliferation and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

The Raf-1/MEK/ERK pathway regulates the expression of the p21(Cip1/Waf1) gene in chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Shared role of the pRB-related p130 and p107 proteins in limb development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

p107 and p130 Coordinately regulate proliferation, Cbfa1 expression, and hypertrophic differentiation during endochondral bone development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Independent roles of Rho-GTPases in growth cone and axonal behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Signalling and crosstalk of Rho GTPases in mediating axon guidance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Regulation of mitogen-activated protein kinases in cardiac myocytes through the small G protein Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Critical activities of Rac1 and Cdc42Hs in skeletal myogenesis: antagonistic effects of JNK and p38 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Mitogen-activated protein kinase p38 mediates regulation of chondrocyte differentiation by parathyroid hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

MAP kinases in chondrocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Rho GTPase-dependent transformation by G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Wnt regulation of chondrocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Integrin-mediated signals regulated by members of the rho family of GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Role of p190RhoGAP in beta 2 integrin regulation of RhoA in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Chondrocyte survival and differentiation in situ are integrin mediated.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Integrins alpha(6A)beta 1 and alpha(6B)beta 1 promote different stages of chondrogenic cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Genetic control of skeletal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Immunohistochemical localization of bone sialoprotein in foetal porcine bone tissues: comparisons with secreted phosphoprotein 1 (SPP-1, osteopontin) and SPARC (osteonectin)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Expression of bone sialoprotein (BSP) in developing human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Inhibition of Rho at different stages of thymocyte development gives different perspectives on Rho function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Characterization of primary cultures of chondrocytes from type II collagen/beta-galactosidase transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

The cyclin D1 and cyclin A genes are targets of activated PTH/PTHrP receptors in Jansen's metaphyseal chondrodysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

PTHrP modulates chondrocyte differentiation through AP-1 and CREB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

The Rho GTPases have multiple effects on the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

Involvement of alpha5beta1 integrin in matrix interactions and proliferation of chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311427200

21 January 2018

Identifiers

DOI

10.1074/JBC.M311427200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14726536%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference