(Q40600037)

21 September 2017

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title

The metabolism of alicyclic amines to reactive iminium ion intermediates (English)

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21 September 2017

J W Gorrod

1

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21 September 2017

G Aislaitner

series ordinal

2

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21 September 2017

publication date

1 July 1994

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European Journal of Drug Metabolism and Pharmacokinetics

21 September 2017

published in

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21 September 2017

volume

19

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21 September 2017

issue

3

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21 September 2017

page(s)

209-217

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https://scigraph.springernature.com/pub.10.1007/bf03188923

21 September 2017

exact match

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cites work

The metabolism of nicotine-delta 1'(5')-iminium ion, in vivo and in vitro.

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF03188923

The role of cytochromes P-450 and flavin-containing monooxygenase in the metabolism of (S)-nicotine by rabbit lung

21 January 2018

1 reference

12 December 2020

Selective inhibition of alternative oxidative pathways of nicotine metabolism in vitro

1 reference

12 December 2020

Metabolic oxidation of nicotine to chemically reactive intermediates

1 reference

12 December 2020

Metabolic studies on phencyclidine: characterization of a phencyclidine iminium ion metabolite

1 reference

12 December 2020

Cytochrome P-450-dependent nicotine oxidation by liver microsomes of guinea pigs. Immunochemical evidence with antibody against phenobarbital-inducible cytochrome P-450

1 reference

12 December 2020

Nicotine chemistry. 5'-Cyanonicotine

1 reference

12 December 2020

Modification of nicotine toxicity by pretreatment with different drugs

1 reference

12 December 2020

The cholinergic properties of some amino-acid esters and amides

1 reference

12 December 2020

Enzymatic oxidation of nicotine to nicotine 1'(5') iminium ion. A newly discovered intermediate in the metabolism of nicotine.

1 reference

12 December 2020

The enzyme “aldehyde oxidase” is an iminium oxidase. Reaction with nicotine Δ1′(5′) iminium ion

1 reference

12 December 2020

Application of chemical cytochrome P-450 model systems to studies on drug metabolism. IV. Mechanism of piperidine metabolism pathways via an iminium intermediate

1 reference

12 December 2020

Nicotine delta 1 "(5)' iminium ion: a reactive intermediate in nicotine metabolism

1 reference

12 December 2020

A nuclear magnetic resonance study of sparteine delta metabolite structure

1 reference

12 December 2020

Rabbit nasal cytochrome P-450 NMa has high activity as a nicotine oxidase

1 reference

12 December 2020

Enzymatic pathway for the formation of cotinine, a major metabolite of nicotine in rabbit liver

1 reference

12 December 2020

Trapping of reactive intermediates by incorporation of 14C-sodium cyanide during microsomal oxidation

1 reference

12 December 2020

Metabolism-dependent covalent binding of (S)-[5-3H]nicotine to liver and lung microsomal macromolecules

1 reference

12 December 2020

Trapping of metabolically generated electrophilic species with cyanide ion: metabolism of 1-benzylpyrrolidine

1 reference

12 December 2020

Stereochemical studies on the cytochrome P-450 catalyzed oxidation of (S)-nicotine to the (S)-nicotine delta 1'(5')-iminium species

1 reference

12 December 2020

Role of 1-methyl-4-phenylpyridinium ion formation and accumulation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity to isolated hepatocytes

1 reference

12 December 2020

Regio- and stereochemical studies on the alpha-carbon oxidation of (S)-nicotine by cytochrome P-450 model systems

1 reference

12 December 2020

Metabolic N-demethylation of nicotine. Trapping of a reactive iminium species with cyanide ion

1 reference

12 December 2020

Characterization of hamster liver nicotine metabolism. I. Relative rates of microsomal C and N oxidation.

1 reference

12 December 2020

Enzymatic oxidation of xenobiotic chemicals

1 reference

12 December 2020

Studies on the in vitro conversion of haloperidol to a potentially neurotoxic pyridinium metabolite

1 reference

12 December 2020

Dissociation of covalent protein adduct formation from oxidative injury in cultured hepatocytes exposed to cocaine.

1 reference

12 December 2020

Dehydration is the first step in the bioactivation of haloperidol to its pyridinium metabolite

1 reference

12 December 2020

Metabolic formation of iminium species: metabolism of phencyclidine

1 reference

12 December 2020

Metabolism of phencyclidine. The role of iminium ion formation in covalent binding to rabbit microsomal protein

1 reference

12 December 2020

Participation of cytochrome P-450 in nicotine oxidation

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF03188923

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Dimensions Publication ID

21 September 2017

1020801975

0 references

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