(Q40602934)

21 September 2017

Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways (English)

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21 September 2017

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Gianfranco Alpini

1

1 reference

21 September 2017

Noriatsu Kanno

2

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21 September 2017

Jo Lynne Phinizy

3

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21 September 2017

Shannon Glaser

4

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21 September 2017

Heather Francis

5

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21 September 2017

Silvia Taffetani

6

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21 September 2017

Gene LeSage

7

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21 September 2017

language of work or name

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30 December 2003

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American Journal of Physiology - Gastrointestinal and Liver Physiology

21 September 2017

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21 September 2017

286

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21 September 2017

6

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21 September 2017

G973-82

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Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha

21 September 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Bile acid feeding increased proliferative activity and apical bile acid transporter expression in both small and large rat cholangiocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Effect of glucagon on intracellular pH regulation in isolated rat hepatocyte couplets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Protein kinases C-gamma and -delta are involved in insulin-like growth factor I-induced migration of colonic epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Protein kinase C-alpha activity inversely modulates invasion and growth of intestinal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Tauroursodeoxycholic acid stimulates hepatocellular exocytosis and mobilizes extracellular Ca++ mechanisms defective in cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

An osmosensing signal transduction pathway in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Bile salt stimulation of colonic epithelial proliferation. Evidence for involvement of lipoxygenase products

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Cellular distribution of thrombomodulin as an early marker for warm ischemic liver injury in porcine liver transplantation: protective effect of prostaglandin I2 analogue and tauroursodeoxycholic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Endogenous cholecystokinin regulates growth of human cholangiocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Involvement of vasoactive intestinal peptide on insulin-like growth factor I-induced proliferation of rat pituitary lactotropes in primary culture: evidence for an autocrine and/or paracrine regulatory system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Protein kinase Calpha negatively regulates cell spreading and motility in MDA-MB-231 human breast cancer cells downstream of epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Ablation of PLB exacerbates ischemic injury to a lesser extent in female than male mice: protective role of NO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Gastrin inhibits cholangiocyte growth in bile duct-ligated rats by interaction with cholecystokinin-B/Gastrin receptors via D-myo-inositol 1,4,5-triphosphate-, Ca(2+)-, and protein kinase C alpha-dependent mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Bile acids stimulate cFLIP phosphorylation enhancing TRAIL-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Gastrin inhibits cholangiocarcinoma growth through increased apoptosis by activation of Ca2+-dependent protein kinase C-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Stimulation of alpha2-adrenergic receptor inhibits cholangiocarcinoma growth through modulation of Raf-1 and B-Raf activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Biliary adenocarcinoma. Characterisation of three new human tumor cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Protein kinase Calpha isoform regulates the activation of the MAP kinase ERK1/2 in human glioma cells: involvement in cell survival and gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Insulin inhibits secretin-induced ductal secretion by activation of PKC alpha and inhibition of PKA activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

The eta isoform of protein kinase C inhibits UV-induced activation of caspase-3 in normal human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

The extended protein kinase C superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Effects of deoxycholate on human colon cancer cells: apoptosis or proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Expression of protein kinase C isoenzymes in colorectal cancer tissue and their differential activation by different bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Ursodiol for the long-term treatment of primary biliary cirrhosis. The UDCA-PBC Study Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Endoscopic application of photodynamic therapy for cholangiocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Tauroursodeoxycholic acid protects in vitro models of human colonic cancer cells from cytotoxic effects of hydrophobic bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Cyclooxygenase-2 and ERBB-2 in cholangiocarcinoma: potential therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Human cholangiocarcinomas express somatostatin receptors and respond to somatostatin with growth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00270.2003

21 January 2018

Identifiers

DOI

10.1152/AJPGI.00270.2003

1 reference

21 September 2017

1 reference