(Q40605303)

22 September 2017

title

Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines (English)

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22 September 2017

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Lan Wu

1

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22 September 2017

Wendell Nicholson

2

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22 September 2017

Susan M Knobel

3

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22 September 2017

Robert J Steffner

4

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22 September 2017

James M May

5

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22 September 2017

David W Piston

6

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22 September 2017

Alvin C Powers

7

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22 September 2017

language of work or name

English

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publication date

19 December 2003

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Journal of Biological Chemistry

22 September 2017

published in

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22 September 2017

volume

279

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22 September 2017

issue

13

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22 September 2017

page(s)

12126-12134

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Metabolic coupling factors in pancreatic beta-cell signal transduction

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytes

21 January 2018

1 reference

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Mammalian glucokinase and its gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection

21 January 2018

1 reference

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The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society

21 January 2018

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Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?

21 January 2018

1 reference

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Concordant Glucose Induction of Glucokinase, Glucose Usage, and Glucose-Stimulated Insulin Release in Pancreatic Islets Maintained in Organ Culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Adaptation to hyperglycemia enhances insulin secretion in glucokinase mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Regulatory effects of glucose on the catalytic activity and cellular content of glucokinase in the pancreatic beta cell. Study using cultured rat islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

In situ glucose uptake and glucokinase activity of pancreatic islets in diabetic and obese rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Increased catalytic activity of glucokinase in isolated islets from hyperinsulinemic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids

21 January 2018

1 reference

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Comparison of insulin secretory function in two mouse models with different susceptibility to beta-cell failure

21 January 2018

1 reference

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Modulation of glucose responsiveness of insulinoma beta-cells by graded overexpression of glucokinase

21 January 2018

1 reference

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Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations

21 January 2018

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Requirement for GSH in recycling of ascorbic acid in endothelial cells

21 January 2018

1 reference

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Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

A role for glutathione peroxidase in protecting pancreatic beta cells against oxidative stress in a model of glucose toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Increased susceptibility to streptozotocin-induced beta-cell apoptosis and delayed autoimmune diabetes in alkylpurine-DNA-N-glycosylase-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology

21 January 2018

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Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

21 January 2018

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Lipid peroxidation-induced membrane structural alterations

21 January 2018

1 reference

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Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Acute Glucose Intolerance in Insulinoma Cells with Unbalanced Overexpression of Glucokinase

21 January 2018

1 reference

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Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants

21 January 2018

1 reference

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Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients.

21 January 2018

1 reference

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Biochemistry and molecular cell biology of diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Fundamental metabolic differences between hepatocytes and islet beta-cells revealed by glucokinase overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

Superoxide dismutase as a target for the selective killing of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307097200

21 January 2018

Identifiers

DOI

10.1074/JBC.M307097200

1 reference

release_r72v4ee6ijhfrkwz7xgdurufkm

22 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/r72v4ee6ijhfrkwz7xgdurufkm

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference