(Q40613981)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Schizophrenia susceptibility pathway neuregulin 1-ErbB4 suppresses Src upregulation of NMDA receptors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

0 references

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Graham M Pitcher

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Lorraine V Kalia

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

David Ng

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Nathalie M Goodfellow

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Kathleen T Yee

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Michael W Salter

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

language of work or name

English

0 references

publication date

27 March 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

470-478

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nm.2315

26 January 2020

exact match

0 references

cites work

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Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia

22 September 2017

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Behavioural characterization of neuregulin 1 type I overexpressing transgenic mice

22 September 2017

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Executive function, neural circuitry, and genetic mechanisms in schizophrenia

22 September 2017

1 reference

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A 5' promoter region SNP in NRG1 is associated with schizophrenia risk and type III isoform expression

22 September 2017

1 reference

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Functional integration between the posterior hippocampus and prefrontal cortex is impaired in both first episode schizophrenia and the at risk mental state

22 September 2017

1 reference

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Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex

22 September 2017

1 reference

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Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components

22 September 2017

1 reference

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The role of oscillations and synchrony in cortical networks and their putative relevance for the pathophysiology of schizophrenia

22 September 2017

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A neural coding scheme formed by the combined function of gamma and theta oscillations.

22 September 2017

1 reference

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Control of excitatory synaptic transmission by C-terminal Src kinase

22 September 2017

1 reference

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Elevated neuregulin-1 and ErbB4 protein in the prefrontal cortex of schizophrenic patients

22 September 2017

1 reference

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Neuregulin-1 enhances depolarization-induced GABA release

22 September 2017

1 reference

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Neuregulin1 (NRG1) signaling through Fyn modulates NMDA receptor phosphorylation: differential synaptic function in NRG1+/- knock-outs compared with wild-type mice.

22 September 2017

1 reference

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Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia

22 September 2017

1 reference

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NMDA receptor subunits: function and pharmacology.

22 September 2017

1 reference

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Modeling of context-dependent retrieval in hippocampal region CA1: implications for cognitive function in schizophrenia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

PSD-95 is a negative regulator of the tyrosine kinase Src in the NMDA receptor complex

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Progress towards validating the NMDA receptor hypofunction hypothesis of schizophrenia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

The involvement of ErbB4 with schizophrenia: association and expression studies

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Activity-driven postsynaptic translocation of CaMKII.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

The c-Src tyrosine kinase associates with the catalytic domain of ErbB-2: implications for ErbB-2 mediated signaling and transformation.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Src kinases: a hub for NMDA receptor regulation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Converging Evidence of NMDA Receptor Hypofunction in the Pathophysiology of Schizophrenia

22 September 2017

1 reference

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Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt

22 September 2017

1 reference

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Neural and mammary gland defects in ErbB4 knockout mice genetically rescued from embryonic lethality

22 September 2017

1 reference

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Ligand-dependent recruitment of the ErbB4 signaling complex into neuronal lipid rafts

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Neuregulin 1 and susceptibility to schizophrenia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Gain control of N-methyl-D-aspartate receptor activity by receptor-like protein tyrosine phosphatase alpha

22 September 2017

1 reference

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Tyrosine phosphatase STEP is a tonic brake on induction of long-term potentiation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Proteomics in neuroscience: from protein to network.

22 September 2017

1 reference

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Convergence of PKC-dependent kinase signal cascades on NMDA receptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Regulation of neuregulin signaling by PSD-95 interacting with ErbB4 at CNS synapses

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

The glutamate receptor ion channels

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Activity-dependent regulation of Neu differentiation factor/neuregulin expression in rat brain

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

NMDA channel regulation by channel-associated protein tyrosine kinase Src.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Long-term potentiation increases tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit 2B in rat dentate gyrus in vivo

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Enhanced tyrosine phosphorylation of the 2B subunit of the N-methyl-D-aspartate receptor in long-term potentiation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

ErbB4 is a suppressor of long-term potentiation in the adult hippocampus

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G alpha q, protein kinase C, and activation of Src.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Neuregulin-1 reverses long-term potentiation at CA1 hippocampal synapses.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Association study of neuregulin 1 gene with schizophrenia.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

The role of hippocampus dysfunction in deficient memory encoding and positive symptoms in schizophrenia.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Cognition in transmembrane domain neuregulin 1 mutant mice.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Neuregulin blocks synaptic strengthening after epileptiform activity in the rat hippocampus

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Disruption to social dyadic interactions but not emotional/anxiety-related behaviour in mice with heterozygous 'knockout' of the schizophrenia risk gene neuregulin-1.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

First in vivo evidence of an NMDA receptor deficit in medication-free schizophrenic patients

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Regulation of NMDA receptors by neuregulin signaling in prefrontal cortex.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Src activation in the induction of long-term potentiation in CA1 hippocampal neurons.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264662

Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21441918

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Further evidence for association between ErbB4 and schizophrenia and influence on cognitive intermediate phenotypes in healthy controls

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21441918

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NM.2315

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21441918%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference