(Q40617990)

English

Comparing myotoxic effects of squalene synthase inhibitor, T-91485, and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors in human myocytes

scientific article published on December 1, 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

22 September 2017

Comparing myotoxic effects of squalene synthase inhibitor, T-91485, and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors in human myocytes (English)

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Europe PubMed Central

PubMed publication ID

22 September 2017

1 reference

10.1016/J.BCP.2003.08.011

https://api.crossref.org/works/10.1016/J.BCP.2003.08.011

31 March 2024

1 reference

10.1016/J.BCP.2003.08.011

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31 March 2024

author name string

Tomoyuki Nishimoto

1

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Europe PubMed Central

PubMed publication ID

22 September 2017

Ryuichi Tozawa

2

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Europe PubMed Central

PubMed publication ID

22 September 2017

Yuichiro Amano

3

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Europe PubMed Central

PubMed publication ID

22 September 2017

Takeo Wada

4

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Europe PubMed Central

PubMed publication ID

22 September 2017

Yoshimi Imura

5

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22 September 2017

Yasuo Sugiyama

6

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22 September 2017

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publication date

1 December 2003

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22 September 2017

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https://api.elsevier.com/content/article/PII:S0006295203006312?httpAccept=text/xml

1 reference

10.1016/J.BCP.2003.08.011

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31 March 2024

https://api.elsevier.com/content/article/PII:S0006295203006312?httpAccept=text/plain

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10.1016/J.BCP.2003.08.011

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Biochemical Pharmacology

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22 September 2017

66

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PubMed publication ID

22 September 2017

11

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22 September 2017

2133-2139

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22 September 2017

Statin therapy and reductions in low-density lipoprotein cholesterol: initial clinical data on the potent new statin Rosuvastatin

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Comparative evaluation of the safety and efficacy of HMG-CoA reductase inhibitor monotherapy in the treatment of primary hypercholesterolemia

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Treating patients with documented atherosclerosis to National Cholesterol Education Program-recommended low-density-lipoprotein cholesterol goals with atorvastatin, fluvastatin, lovastatin and simvastatin.

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HMG-CoA reductase inhibitors and myotoxicity

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Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro

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HMG CoA reductase inhibitor-induced myotoxicity: pravastatin and lovastatin inhibit the geranylgeranylation of low-molecular-weight proteins in neonatal rat muscle cell culture

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FDA adverse event reports on statin-associated rhabdomyolysis

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Comparison of properties of four inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

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Drug treatment of lipid disorders

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ACC/AHA/NHLBI Clinical Advisory on the Use and Safety of Statins

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Cerivastatin and reports of fatal rhabdomyolysis

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Synthesis of novel 4,1-benzoxazepine derivatives as squalene synthase inhibitors and their inhibition of cholesterol synthesis

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Lipid-lowering properties of TAK-475, a squalene synthase inhibitor, in vivo and in vitro

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Lipid-lowering effects of TAK-475, a squalene synthase inhibitor, in animal models of familial hypercholesterolemia

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Simvastatin modulates cytokine-mediated endothelial cell adhesion molecule induction: involvement of an inhibitory G protein

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Inhibition of human vascular smooth muscle cell proliferation by lovastatin: the role of isoprenoid intermediates of cholesterol synthesis

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Merosin and laminin in myogenesis; specific requirement for merosin in myotube stability and survival

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3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase and Isoprenylation Inhibitors Induce Apoptosis of Vascular Smooth Muscle Cells in Culture

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Evaluation of the synergistic adverse effects of concomitant therapy with statins and fibrates on rhabdomyolysis

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Myopathy induced by HMG-CoA reductase inhibitors in rabbits: a pathological, electrophysiological, and biochemical study.

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Decreases in serum ubiquinone concentrations do not result in reduced levels in muscle tissue during short-term simvastatin treatment in humans

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The effect of simvastatin treatment on natural antioxidants in low-density lipoproteins and high-energy phosphates and ubiquinone in skeletal muscle

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Lovastatin increases exercise-induced skeletal muscle injury

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Fluvastatin induces apoptosis in rat neonatal cardiac myocytes: a possible mechanism of statin-attenuated cardiac hypertrophy

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Statin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-I

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Identifiers

10.1016/J.BCP.2003.08.011

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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