(Q40624347)

22 September 2017

Suppression of adriamycin-induced apoptosis by sustained activation of the phosphatidylinositol-3'-OH kinase-Akt pathway (English)

1 reference

22 September 2017

Kenji Takeuchi

1

1 reference

PubMed ID

14570904

22 September 2017

Fumiaki Ito

series ordinal

2

1 reference

PubMed ID

14570904

22 September 2017

language of work or name

English

0 references

publication date

21 October 2003

1 reference

Journal of Biological Chemistry

22 September 2017

1 reference

22 September 2017

279

1 reference

22 September 2017

2

1 reference

22 September 2017

892-900

1 reference

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Differential requirement for caspase 9 in apoptotic pathways in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Induction of apoptosis by the Bcl-2 homologue Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

p53-dependent and p53-independent activation of apoptosis in mammary epithelial cells reveals a survival function of EGF and insulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Scatter factor protects epithelial and carcinoma cells against apoptosis induced by DNA-damaging agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Hepatocyte growth factor/scatter factor blocks the mitochondrial pathway of apoptosis signaling in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Purification and subunit structure of hepatocyte growth factor from rat platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Evidence for the identity of human scatter factor and human hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Phosphoinositide 3-kinase induces scattering and tubulogenesis in epithelial cells through a novel pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Hepatocyte growth factor rapidly induces the tyrosine phosphorylation of 41-kDa and 43-kDa proteins in mouse keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Activation of the 41/43 kDa mitogen-activated protein kinase signaling pathway is required for hepatocyte growth factor-induced cell scattering

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Dissociation of c-fos induction and mitogen-activated-protein kinase activation from the hepatocyte-growth-factor-induced motility response in human gastric carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Activated type I phosphatidylinositol kinase is associated with the epidermal growth factor (EGF) receptor following EGF stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Negative regulation of the forkhead transcription factor FKHR by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Native and recombinant human hepatocyte growth factors are highly potent promoters of DNA synthesis in both human and rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

A rapid and simple method for the isolation of apoptotic DNA fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Functional role of interleukin 1 beta (IL-1 beta) in IL-1 beta-converting enzyme-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Signaling pathways leading to transcription and translation cooperatively regulate the transient increase in expression of c-Fos protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

p120cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Akt regulates cell survival and apoptosis at a postmitochondrial level

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Cbl: many adaptations to regulate protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Epidermal growth factor, but not hepatocyte growth factor, suppresses the apoptosis induced by transforming growth factor-beta in fetal hepatocytes in primary culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

The cytokine hepatocyte growth factor/scatter factor inhibits apoptosis and enhances DNA repair by a common mechanism involving signaling through phosphatidyl inositol 3' kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

EGF induces tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

p53 status and the efficacy of cancer therapy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306615200

21 January 2018

Identifiers

DOI

10.1074/JBC.M306615200

1 reference

22 September 2017

1 reference

PubMed ID

14570904