(Q40630378)

English

WAY‐855 (3‐amino‐tricyclo[2.2.1.02.6]heptane‐1,3‐dicarboxylic acid): a novel, EAAT2‐preferring, nonsubstrate inhibitor of high‐affinity glutamate uptake

scientific article published on September 29, 2003

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

WAY-855 (3-amino-tricyclo[2.2.1.02.6]heptane-1,3-dicarboxylic acid): a novel, EAAT2-preferring, nonsubstrate inhibitor of high-affinity glutamate uptake (English)

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

WAY‐855 (3‐amino‐tricyclo[2.2.1.02.6]heptane‐1,3‐dicarboxylic acid): a novel, EAAT2‐preferring, nonsubstrate inhibitor of high‐affinity glutamate uptake (English)

1 reference

10.1038/SJ.BJP.0705509

https://api.crossref.org/works/10.1038/SJ.BJP.0705509

15 March 2024

1 reference

10.1038/SJ.BJP.0705509

https://api.crossref.org/works/10.1038/SJ.BJP.0705509

15 March 2024

author name string

John Dunlop

1

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Scott Eliasof

2

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Gary Stack

3

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Alexander Greenfield

5

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Dianne Kowal

6

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Robert Petroski

7

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Tikva Carrick

8

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

H. Beal McIlvain

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517179

15 March 2024

language of work or name

0 references

publication date

29 September 2003

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

full work available at URL

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1038/sj.bjp.0705509

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517179

15 March 2024

https://europepmc.org/articles/PMC1574101

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517179

15 March 2024

https://europepmc.org/articles/PMC1574101?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517179

15 March 2024

https://doi.org/10.1038/sj.bjp.0705509

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14517179

15 March 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1038%2Fsj.bjp.0705509

1 reference

10.1038/SJ.BJP.0705509

https://api.crossref.org/works/10.1038/SJ.BJP.0705509

15 March 2024

https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1038/sj.bjp.0705509

1 reference

10.1038/SJ.BJP.0705509

https://api.crossref.org/works/10.1038/SJ.BJP.0705509

15 March 2024

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

140

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

5

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

839-846

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

Glutamate uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

Differentiation of substrate and nonsubstrate inhibitors of the high-affinity, sodium-dependent glutamate transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

Pharmacological agents acting at subtypes of metabotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

Recent excitement in the ionotropic glutamate receptor field

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

A pharmacological review of competitive inhibitors and substrates of high-affinity, sodium-dependent glutamate transport in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

DL-threo-beta-benzyloxyaspartate, a potent blocker of excitatory amino acid transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

Synaptic activation of glutamate transporters in hippocampal astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

Pharmacology and functions of metabotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

An excitatory amino-acid transporter with properties of a ligand-gated chloride channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

Cloning and expression of a rat brain L-glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

Primary structure and functional characterization of a high-affinity glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

22 September 2017

Substrate exchange properties of the high-affinity glutamate transporter EAAT2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

25 September 2017

Inducible expression and pharmacology of the human excitatory amino acid transporter 2 subtype of L-glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

25 September 2017

Expression of the GLT-1 subtype of Na+-dependent glutamate transporter: pharmacological characterization and lack of regulation by protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

25 September 2017

A [35S]GTPgammaS binding assessment of metabotropic glutamate receptor standards in Chinese hamster ovary cell lines expressing the human metabotropic receptor subtypes 2 and 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

25 September 2017

Ionotropic glutamate receptors: new types and new concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

17 June 2018

Contrasting modes of action of methylglutamate derivatives on the excitatory amino acid transporters, EAAT1 and EAAT2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

17 June 2018

(2S,3S,4R)-2-(carboxycyclopropyl)glycine, a potent and competitive inhibitor of both glial and neuronal uptake of glutamate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

17 June 2018

Pharmacologically distinct sodium-dependent L-[3H]glutamate transport processes in rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

17 June 2018

Conformationally defined neurotransmitter analogs. Selective inhibition of glutamate uptake by one pyrrolidine-2,4-dicarboxylate diastereomer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

17 June 2018

Effects of threo-beta-hydroxyaspartate derivatives on excitatory amino acid transporters (EAAT4 and EAAT5).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

20 August 2018

Dihydrokainate-sensitive neuronal glutamate transport is required for protection of rat cortical neurons in culture against synaptically released glutamate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

20 August 2018

Anion currents and predicted glutamate flux through a neuronal glutamate transporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574101

20 August 2018

Inhibition of high affinity l-glutamic acid uptake into rat cortical synaptosomes by the conformationally restricted analogue of glutamic acid, cis-1-aminocyclobutane-1,3-dicarboxylic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-TRANs-Pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1, 3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/14517179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0705509

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 September 2017

ResearchGate publication ID

0 references

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