(Q40635924)

English

A novel rationale for inhibition of gelatinase B in multiple sclerosis: MMP-9 destroys alpha B-crystallin and generates a promiscuous T cell epitope.

scientific article published on August 2003

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

A novel rationale for inhibition of gelatinase B in multiple sclerosis: MMP-9 destroys alpha B-crystallin and generates a promiscuous T cell epitope (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

multiple sclerosis

0 references

Johannes M van Noort

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Philippe E Van den Steen

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Ghislain Opdenakker

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

author name string

Sofie Starckx

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Richard Verbeek

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 August 2003

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

number of pages

11

1 reference

based on heuristic

inferred from page(s)

Journal of Neuroimmunology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

141

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1-2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

47-57

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Matrix metalloproteinase expression in an experimentally-induced DTH model of multiple sclerosis in the rat CNS.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of αB-crystallin in glia cells during lesional development in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Presentation of alpha B-crystallin to T cells in active multiple sclerosis lesions: an early event following inflammatory demyelination

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The degenerative effect of a single intranigral injection of LPS on the dopaminergic system is prevented by dexamethasone, and not mimicked by rh-TNF-alpha, IL-1beta and IFN-gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Small heat-shock proteins and their potential role in human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Plasminogen activators and matrix metalloproteases, mediators of extracellular proteolysis in inflammatory demyelination of the central nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The Expression of Tissue-type Plasminogen Activator, Matrix Metalloproteases and Endogenous Inhibitors in the Central Nervous System in Multiple Sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of Gelatinases in Complex Biological Fluids and Tissue Extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Gelatinase B is diabetogenic in acute and chronic pancreatitis by cleaving insulin.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance of young gelatinase B-deficient mice to experimental autoimmune encephalomyelitis and necrotizing tail lesions.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The heat shock response reduces myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Matrix metalloproteinases in the normal human central nervous system, microglial nodules, and multiple sclerosis lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Human hepatoma cells produce an 85 kDa gelatinase regulated by phorbol 12-myristate 13-acetate.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Stromelysin-1 and gelatinase A are upregulated before TNF-alpha in LPS-stimulated neuroinflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytokine-regulated proteases in autoimmune diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of gelatinases and IL-6 in the cerebrospinal fluid of patients with optic neuritis, multiple sclerosis and other inflammatory neurological diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Monoclonal Antibodies Specific for Natural Human Neutrophil Gelatinase B Used for Affinity Purification, Quantitation by Two-Site ELISA and Inhibition of Enzymatic Activity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Leukocyte Gelatinase B Cleavage Releases Encephalitogens from Human Myelin Basic Protein

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Matrix metalloproteinases in neuroinflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Encephalitogenic and immunogenic potential of the stress protein alphaB-crystallin in Biozzi ABH (H-2A(g7)) mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9)

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleavage of denatured natural collagen type II by neutrophil gelatinase B reveals enzyme specificity, post-translational modifications in the substrate, and the formation of remnant epitopes in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Do heat shock proteins control the balance of T-cell regulation in inflammatory diseases?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

HSP70 protects against TNF-induced lethal inflammatory shock.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

The small heat-shock protein αB-crystallin as candidate autoantigen in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

T cells discriminate between differentially phosphorylated forms of alphaB-crystallin, a major central nervous system myelin antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Tolerance controls encephalitogenicity of alphaB-crystallin in the Lewis rat

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

T- and B-cell nonresponsiveness to self-alphaB-crystallin in SJL mice prevents the induction of experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of heat shock proteins in protection from and pathogenesis of infectious diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-5728%2803%2900217-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0165-5728(03)00217-0

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12965253%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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