(Q40635962)

22 September 2017

title

Enhanced CAR T-cell engineering using non-viral Sleeping Beauty transposition from minicircle vectors (English)

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22 September 2017

8

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22 September 2017

R Monjezi

1

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22 September 2017

C Miskey

2

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22 September 2017

T Gogishvili

3

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22 September 2017

M Schleef

4

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22 September 2017

M Schmeer

5

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22 September 2017

H Einsele

6

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22 September 2017

Z Ivics

7

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22 September 2017

publication date

5 August 2016

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22 September 2017

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22 September 2017

volume

31

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22 September 2017

issue

1

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22 September 2017

page(s)

186-194

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Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Chimeric antigen receptor T cells for sustained remissions in leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Comparison of lentiviral and sleeping beauty mediated αβ T cell receptor gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Analysis of lentiviral vector integration in HIV+ study subjects receiving autologous infusions of gene modified CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Translating Sleeping Beauty transposition into cellular therapies: victories and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

The Sleeping Beauty transposon system for clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Sleeping Beauty transposon-mediated engineering of human primary T cells for therapy of CD19+ lymphoid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Manufacture of clinical-grade CD19-specific T cells stably expressing chimeric antigen receptor using Sleeping Beauty system and artificial antigen presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

A new approach to gene therapy using Sleeping Beauty to genetically modify clinical-grade T cells to target CD19

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2016.180

Adoptive cellular therapy: a race to the finish line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Use of minicircle plasmids for gene therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

A robust system for production of minicircle DNA vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Minicircle-DNA production by site specific recombination and protein-DNA interaction chromatography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Minicircle DNA electrotransfer for efficient tissue-targeted gene delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Performance of high quality minicircle DNA for in vitro and in vivo gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Efficient sleeping beauty DNA transposition from DNA minicircles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Biophotonic cytotoxicity assay for high-throughput screening of cytolytic killing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Development of hyperactive sleeping beauty transposon vectors by mutational analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Dynamic regulation of nucleosome positioning in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Gene Insertion Into Genomic Safe Harbors for Human Gene Therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Sleeping Beauty, a wide host-range transposon vector for genetic transformation in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Size-dependent DNA mobility in cytoplasm and nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

RNA as a source of transposase for Sleeping Beauty-mediated gene insertion and expression in somatic cells and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

High-resolution genome-wide mapping of transposon integration in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Chromatin landscapes of retroviral and transposon integration profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Comparative analysis of transposable element vector systems in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Gene transfer efficiency and genome-wide integration profiling of Sleeping Beauty, Tol2, and piggyBac transposons in human primary T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Retargeting sleeping beauty transposon insertions by engineered zinc finger DNA-binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Targeted Sleeping Beauty transposition in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Adoptive therapy with chimeric antigen receptor-modified T cells of defined subset composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.180

Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27491640

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Safe harbours for the integration of new DNA in the human genome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27491640

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/LEU.2016.180

1 reference

Dimensions Publication ID

22 September 2017

1004554299

0 references

1 reference