(Q40636642)

22 September 2017

Potent and selective activation of the pancreatic beta-cell type K(ATP) channel by two novel diazoxide analogues (English)

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22 September 2017

M Dabrowski

1

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22 September 2017

T Larsen

2

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22 September 2017

F M Ashcroft

3

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22 September 2017

J Bondo Hansen

4

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22 September 2017

P Wahl

5

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22 September 2017

5 September 2003

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22 September 2017

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22 September 2017

46

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22 September 2017

10

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22 September 2017

1375-1382

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https://scigraph.springernature.com/pub.10.1007/s00125-003-1198-1

22 September 2017

0 references

cites work

Modification of insulin resistance by diazoxide in obese Zucker rats.

1 reference

12 December 2020

Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle

1 reference

12 December 2020

The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide

1 reference

12 December 2020

Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons

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12 December 2020

Physiological and pathophysiological roles of ATP-sensitive K+ channels

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12 December 2020

Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor

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12 December 2020

Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic beta-cells

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12 December 2020

Pharmaco-topology of sulfonylurea receptors. Separate domains of the regulatory subunits of K(ATP) channel isoforms are required for selective interaction with K(+) channel openers

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12 December 2020

Potassium channel openers as potential therapeutic weapons in ion channel disease.

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12 December 2020

6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives potently and selectively activate ATP sensitive potassium channels of pancreatic beta-cells.

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12 December 2020

A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel

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12 December 2020

Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1

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12 December 2020

Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta-cells.

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12 December 2020

C-terminal tails of sulfonylurea receptors control ADP-induced activation and diazoxide modulation of ATP-sensitive K(+) channels

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12 December 2020

Genetics of neonatal hyperinsulinism.

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12 December 2020

A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels

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12 December 2020

Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion

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12 December 2020

Properties of cloned ATP-sensitive K+ currents expressed in Xenopus oocytes.

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12 December 2020

Recent developments in the biology and medicinal chemistry of potassium channel modulators: update from a decade of progress

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12 December 2020

Diazoxide treatment at onset preserves residual insulin secretion in adults with autoimmune diabetes

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12 December 2020

Correlating structure and function in ATP-sensitive K+ channels.

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12 December 2020

Prophylaxis of genetically determined diabetes by diazoxide: a study in a rat model of naturally occurring obese diabetes.

1 reference

12 December 2020

A transmembrane domain of the sulfonylurea receptor mediates activation of ATP-sensitive K(+) channels by K(+) channel openers.

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12 December 2020

Toward understanding the assembly and structure of KATP channels

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12 December 2020

Pharmacological plasticity of cardiac ATP-sensitive potassium channels toward diazoxide revealed by ADP

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12 December 2020

ATP-sensitive K+ channels: a link between B-cell metabolism and insulin secretion

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12 December 2020

Antagonist properties of a phosphono isoxazole amino acid at glutamate R1-4 (R,S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid receptor subtypes.

1 reference

12 December 2020

Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor

1 reference

12 December 2020

10.1007/S00125-003-1198-1

Identifiers

DOI

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22 September 2017

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