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Regulation of human sterol 27-hydroxylase gene (CYP27A1) by bile acids and hepatocyte nuclear factor 4alpha (HNF4alpha).
scientific article published on August 2003
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12957378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12957378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
title
Regulation of human sterol 27-hydroxylase gene (CYP27A1) by bile acids and hepatocyte nuclear factor 4alpha (HNF4alpha)
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12957378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12957378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author
John Chiang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12957378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12957378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author name string
Wenling Chen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12957378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12957378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
language of work or name
English
0 references
publication date
1 August 2003
1 reference
stated in
Europe PubMed Central
PubMed ID
12957378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12957378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
published in
Gene
1 reference
stated in
Europe PubMed Central
PubMed ID
12957378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12957378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
313
1 reference
stated in
Europe PubMed Central
PubMed ID
12957378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12957378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
71-82
1 reference
stated in
Europe PubMed Central
PubMed ID
12957378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12957378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
cites work
Different effects on the expression of CYP7 and CYP27 in rabbit liver by cholic acid and cholestyramine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Removal of cholesterol from extrahepatic sources by oxidative mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differences in the regulation of the classical and the alternative pathway for bile acid synthesis in human liver. No coordinate regulation of CYP7A1 and CYP27A1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of bile acid synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bile acid regulation of gene expression: roles of nuclear hormone receptors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Farnesoid X receptor responds to bile acids and represses cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional analysis of the promoter of human sterol 27-hydroxylase gene in HepG2 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frameshift and splice-junction mutations in the sterol 27-hydroxylase gene cause cerebrotendinous xanthomatosis in Jews or Moroccan origin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a nuclear receptor for bile acids
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vitamin D receptor as an intestinal bile acid sensor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo and in vitro regulation of sterol 27-hydroxylase in the liver during the acute phase response. potential role of hepatocyte nuclear factor-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bile acid induction of cytokine expression by macrophages correlates with repression of hepatic cholesterol 7alpha-hydroxylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple parameters determine the specificity of transcriptional response by nuclear receptors HNF-4, ARP-1, PPAR, RAR and RXR through common response elements.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bile acids: natural ligands for an orphan nuclear receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Down-regulation of the rat hepatic sterol 27-hydroxylase gene by bile acids in transfected primary hepatocytes: possible role of hepatic nuclear factor 1alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional regulation of the human sterol 27-hydroxylase gene (CYP27) and promoter mapping
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Redundant pathways for negative feedback regulation of bile acid production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increasing dietary cholesterol induces different regulation of classic and alternative bile acid synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
On the mechanism of bile acid inhibition of rat sterol 12α-hydroxylase gene (CYP8B1) transcription: roles of α-fetoprotein transcription factor and hepatocyte nuclear factor 4α
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0378-1119%2803%2900631-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0378-1119(03)00631-0
1 reference
stated in
Europe PubMed Central
PubMed ID
12957378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12957378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
PubMed ID
12957378
1 reference
stated in
Europe PubMed Central
PubMed ID
12957378
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12957378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
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