(Q40637957)

22 September 2017

title

Irreversible inhibition of CD13/aminopeptidase N by the antiangiogenic agent curcumin (English)

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22 September 2017

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angiogenesis inhibitor

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Joong Sup Shim

1

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22 September 2017

Jin Hee Kim

2

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22 September 2017

Hyun Young Cho

3

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22 September 2017

Young Na Yum

4

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22 September 2017

Seung Hee Kim

5

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22 September 2017

Hyun-Ju Park

6

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22 September 2017

Bum Sang Shim

7

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22 September 2017

Seung Hoon Choi

8

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22 September 2017

Ho Jeong Kwon

9

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22 September 2017

publication date

1 August 2003

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22 September 2017

published in

Chemistry and Biology

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22 September 2017

volume

10

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22 September 2017

issue

8

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22 September 2017

page(s)

695-704

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Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N

22 September 2017

cites work

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The metabolism of neuropeptides. Phase separation of synaptic membrane preparations with Triton X-114 reveals the presence of aminopeptidase N.

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Human melanoma invasion and metastasis enhancement by high expression of aminopeptidase N/CD13

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Role of aminopeptidase N (CD13) in tumor-cell invasion and extracellular matrix degradation

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CD13/APN is activated by angiogenic signals and is essential for capillary tube formation

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7 January 2021

Betulinic acid inhibits growth factor-induced in vitro angiogenesis via the modulation of mitochondrial function in endothelial cells.

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7 January 2021

Aminopeptidase N is involved in cell motility and angiogenesis: its clinical significance in human colon cancer

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7 January 2021

Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin

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7 January 2021

Antitumor activity of curcumin is mediated through the induction of apoptosis in AK-5 tumor cells

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7 January 2021

Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells

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7 January 2021

Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]

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7 January 2021

Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoyl-phorbol-13-acetate in NIH 3T3 cells

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7 January 2021

Curcuminoids inhibit the angiogenic response stimulated by fibroblast growth factor-2, including expression of matrix metalloproteinase gelatinase B

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Inhibition of tumor invasion and extracellular matrix degradation by ubenimex (bestatin)

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7 January 2021

Potent homophthalimide-type inhibitors of B16F10/L5 mouse melanoma cell invasion

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7 January 2021

Human breast cancer cells activate procollagenase-1 and invade type I collagen: invasion is inhibited by all-trans retinoic acid

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7 January 2021

Strategy and planning for chemopreventive drug development: clinical development plans II.

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What Is the Evidence That Tumors Are Angiogenesis Dependent?

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7 January 2021

Interactions of alpha, beta-unsaturated aldehydes and ketones with human glutathione S-transferase P1-1.

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7 January 2021

Characterization of Glu350 as a critical residue involved in the N-terminal amine binding site of aminopeptidase N (EC 3.4.11.2): insights into its mechanism of action

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7 January 2021

Structure determination and refinement of bovine lens leucine aminopeptidase and its complex with bestatin.

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7 January 2021

Curcumin, a molecule that inhibits the Ca2+-ATPase of sarcoplasmic reticulum but increases the rate of accumulation of Ca2+.

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7 January 2021

Microarray-based analysis of anti-angiogenic activity of demethoxycurcumin on human umbilical vein endothelial cells: crucial involvement of the down-regulation of matrix metalloproteinase

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7 January 2021

Curcumin inhibits cyclooxygenase-2 transcription in bile acid- and phorbol ester-treated human gastrointestinal epithelial cells.

1 reference

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7 January 2021

Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation

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7 January 2021

Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis

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7 January 2021

10.1016/S1074-5521(03)00169-8

Identifiers

DOI

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22 September 2017

1 reference