(Q40644112)

22 September 2017

Apoptosome-independent pathway for apoptosis. Biochemical analysis of APAF-1 defects and biological outcomes (English)

1 reference

22 September 2017

1 reference

Chafké Ahmed Belmokhtar

1

1 reference

22 September 2017

Josette Hillion

2

1 reference

22 September 2017

Charles Dudognon

3

1 reference

22 September 2017

Susana Fiorentino

4

1 reference

22 September 2017

Maria Flexor

5

1 reference

22 September 2017

Michel Lanotte

6

1 reference

22 September 2017

Evelyne Ségal-Bendirdjian

7

1 reference

22 September 2017

language of work or name

English

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publication date

27 May 2003

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Journal of Biological Chemistry

22 September 2017

1 reference

22 September 2017

278

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22 September 2017

32

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22 September 2017

29571-29580

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Apoptosis in cancer therapy: crossing the threshold

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Caspases: the executioners of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Human ICE/CED-3 protease nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Caspases: killer proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Catalytic properties of the caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Caspase structure, proteolytic substrates, and function during apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Mitochondrial control of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Cycloheximide-induced T-cell death is mediated by a Fas-associated death domain-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Differential requirement for caspase 9 in apoptotic pathways in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Caspase-8 and Apaf-1-independent caspase-9 activation in Sendai virus-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

A novel Apaf-1-independent putative caspase-2 activation complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Apoptosis without caspases: an inefficient molecular guillotine?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Studies on the resistance of a murine leukemia L1210 cell line cis-diamminedichloroplatinum (II).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Mitochondrial control of nuclear apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Mitochondrial control of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Cleavage of caspase family members by granzyme B: a comparative study in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Role of multiple cellular proteases in the execution of programmed cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Protease activation during apoptosis: death by a thousand cuts?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Selective Degradation of Abnormal Proteins in Mammalian Tissue Culture Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Ubiquitin-mediated pathways for intracellular proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

A unified model for apical caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Efficient Nuclear Targeting of Granzyme B and the Nuclear Consequences of Apoptosis Induced by Granzyme B and Perforin Are Caspase-dependent, but Cell Death Is Caspase-independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Cisplatin resistance in a murine leukemia cell line is associated with a defective apoptotic process

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

Expression and functional analysis of Apaf-1 isoforms. Extra Wd-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302924200

21 January 2018

Identifiers

DOI

10.1074/JBC.M302924200

1 reference

22 September 2017

1 reference