(Q40648538)

English

Nitrogen-containing bisphosphonates induce S-phase cell cycle arrest and apoptosis of myeloma cells by activating MAPK pathway and inhibiting mevalonate pathway

scientific article published on July 1, 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Nitrogen-containing bisphosphonates induce S-phase cell cycle arrest and apoptosis of myeloma cells by activating MAPK pathway and inhibiting mevalonate pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

1 reference

10.1016/S0898-6568(03)00007-X

https://api.crossref.org/works/10.1016/S0898-6568(03)00007-X

1 January 2024

author name string

Toyotaka Iguchi

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Yoshitaka Miyakawa

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Kaori Yamamoto

3

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Masahiro Kizaki

4

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Yasuo Ikeda

5

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12742232

1 January 2024

publication date

1 July 2003

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

number of pages

9

1 reference

based on heuristic

inferred from page(s)

full work available at URL

https://api.elsevier.com/content/article/PII:S089865680300007X?httpAccept=text/xml

1 reference

10.1016/S0898-6568(03)00007-X

https://api.crossref.org/works/10.1016/S0898-6568(03)00007-X

1 January 2024

https://api.elsevier.com/content/article/PII:S089865680300007X?httpAccept=text/plain

1 reference

10.1016/S0898-6568(03)00007-X

https://api.crossref.org/works/10.1016/S0898-6568(03)00007-X

1 January 2024

Cellular Signalling

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

719-727

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

New insights into role of microenvironment in multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficacy of Pamidronate in Reducing Skeletal Events in Patients with Advanced Multiple Myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumour activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Conflicting actions of parathyroid hormone-related protein and serum calcium as regulators of 25-hydroxyvitamin D(3)-1 alpha-hydroxylase expression in a nude rat model of humoral hypercalcemia of malignancy

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Responses of trabecular and cortical bone turnover and bone mass and strength to bisphosphonate YH529 in ovariohysterectomized beagles with calcium restriction

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein geranylgeranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphonates and GGTI-298.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Nitrogen-bisphosphonates block retinoblastoma phosphorylation and cell growth by inhibiting the cholesterol biosynthetic pathway in a keratinocyte model for esophageal irritation.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of mitogen-activated protein kinase through alpha5/beta1 integrin is required for cell cycle progression of B progenitor cell line, Reh, on human marrow stromal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapid downregulation of cyclin D1 mRNA and protein levels by ultraviolet irradiation in murine macrophage cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A newly developed bisphosphonate, YM529, is a potent apoptosis inducer of human myeloma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

High intensity ERK signal mediates hepatocyte growth factor-induced proliferation inhibition of the human hepatocellular carcinoma cell line HepG2.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2803%2900007-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer Research

5

58

5294

author name string

Shipman

publication date

1998

1 reference

10.1016/S0898-6568(03)00007-X

https://api.crossref.org/works/10.1016/S0898-6568(03)00007-X

1 January 2024

Molecular Pharmacology

9

54

631

author name string

Coxon

publication date

1998

1 reference

10.1016/S0898-6568(03)00007-X

https://api.crossref.org/works/10.1016/S0898-6568(03)00007-X

1 January 2024

Cancer Research

14

61

2602

author name string

Lee

publication date

2001

1 reference

10.1016/S0898-6568(03)00007-X

https://api.crossref.org/works/10.1016/S0898-6568(03)00007-X

1 January 2024

Cancer Research

17

60

1871

author name string

Adjei

publication date

2000

1 reference

10.1016/S0898-6568(03)00007-X

https://api.crossref.org/works/10.1016/S0898-6568(03)00007-X

1 January 2024

Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa B

22

1 reference

10.1016/S0898-6568(03)00007-X

https://api.crossref.org/works/10.1016/S0898-6568(03)00007-X

1 January 2024

Identifiers

10.1016/S0898-6568(03)00007-X

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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