(Q40648702)

22 September 2017

title

Inhibition of HERG K+ current and prolongation of the guinea-pig ventricular action potential by 4-aminopyridine (English)

1 reference

22 September 2017

Inhibition of HERG K+ Current and Prolongation of the Guinea‐Pig Ventricular Action Potential by 4‐Aminopyridine (English)

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2003.043976

voltage-gated potassium channel

1 January 2024

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12740430

cation transport proteins

1 January 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12740430

1 January 2024

trans-activators

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12740430

1 January 2024

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2003.043976

1 January 2024

author name string

J. M. Ridley

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12740430

1 January 2024

J. T. Milnes

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12740430

1 January 2024

Y. H. Zhang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12740430

1 January 2024

H. J. Witchel

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12740430

1 January 2024

J. C. Hancox

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12740430

1 January 2024

language of work or name

English

0 references

publication date

9 May 2003

1 reference

full work available at URL

22 September 2017

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2342986

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12740430

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1113%2Fjphysiol.2003.043976

1 January 2024

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2003.043976

https://onlinelibrary.wiley.com/doi/pdf/10.1113/jphysiol.2003.043976

1 January 2024

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2003.043976

https://onlinelibrary.wiley.com/doi/full-xml/10.1113/jphysiol.2003.043976

1 January 2024

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2003.043976

https://physoc.onlinelibrary.wiley.com/doi/pdf/10.1113/jphysiol.2003.043976

1 January 2024

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2003.043976

1 January 2024

published in

Journal of Physiology

1 reference

22 September 2017

volume

549

1 reference

22 September 2017

issue

Pt 3

1 reference

22 September 2017

page(s)

667-672

1 reference

Rate-dependent changes in action potential duration and membrane currents in hamster ventricular myocytes

22 September 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Blocking effects of the antiarrhythmic drug propafenone on the HERG potassium channel

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Inhibition of HERG potassium channel current by the class 1a antiarrhythmic agent disopyramide

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Mathematical models of action potentials in the periphery and center of the rabbit sinoatrial node.

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Biophysical properties and molecular basis of cardiac rapid and slow delayed rectifier potassium channels.

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Characteristics of a transient outward current (sensitive to 4-aminopyridine) in Ca2+-tolerant myocytes isolated from the rabbit atrioventricular node.

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Characterisation of Kv4.3 in HEK293 cells: comparison with the rat ventricular transient outward potassium current

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Alteration of HERG current profile during the cardiac ventricular action potential, following a pore mutation.

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Time course and voltage dependence of expressed HERG current compared with native "rapid" delayed rectifier K current during the cardiac ventricular action potential

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Transient outward potassium current and repolarization of cardiac cells

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

The inward rectification mechanism of the HERG cardiac potassium channel

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Characterization of 4-aminopyridine block of the transient outward K+ current in adult rat ventricular myocytes.

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

A family of potassium channel genes related to eag in Drosophila and mammals

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Effects of flecainide, quinidine, and 4-aminopyridine on transient outward and ultrarapid delayed rectifier currents in human atrial myocytes.

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Calcium tolerant ventricular myocytes prepared by preincubation in a "KB medium".

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Repolarization differences between guinea pig atrial endocardium and epicardium: evidence for a role of Ito.

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

T wave changes persisting after ventricular pacing in canine heart are altered by 4-aminopyridine but not by lidocaine. Implications with respect to phenomenon of cardiac 'memory'

12 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2342986

Female gender is a risk factor for torsades de pointes in an in vitro animal model

12 October 2018

1 reference

12 December 2020

Characterisation of the transient outward K+ current in rabbit sinoatrial node cells

1 reference

12 December 2020

Evidence for two components of delayed rectifier K+ current in human ventricular myocytes

1 reference

12 December 2020

Effect on the fura-2 transient of rapidly blocking the Ca2+ channel in electrically stimulated rabbit heart cells

1 reference

12 December 2020

Characterization of an ultrarapid delayed rectifier potassium channel involved in canine atrial repolarization

1 reference

12 December 2020

The effects of barium, dofetilide and 4-aminopyridine (4-AP) on ventricular repolarization in normal and hypertrophied rabbit heart

1 reference

12 December 2020

Frequency-dependent effects of 4-aminopyridine and almokalant on action-potential duration of adult and neonatal rabbit ventricular muscle

1 reference

12 December 2020

Characteristics of transient outward K+ current in human atrial cardiomyocytes

1 reference

12 December 2020

Dose-dependence of 4-aminopyridine plasma concentrations and electrophysiological effects in dogs : potential relevance to ionic mechanisms in vivo

1 reference

12 December 2020

Survivin Inhibitors Mitigate Chemotherapeutic Resistance in Breast Cancer Cells by Suppressing Genotoxic Nuclear Factor-κB Activation

23

1 reference

https://api.crossref.org/works/10.1113/JPHYSIOL.2003.043976

1 January 2024

Identifiers

1 reference

release_no52fn67drd2dlwjunpjibeei4

22 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/no52fn67drd2dlwjunpjibeei4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2342986

0 references

1 reference