(Q40659371)

22 September 2017

title

Bcl-2 promotes premature senescence induced by oncogenic Ras. (English)

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22 September 2017

Bálint Tombor

1

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22 September 2017

Kathleen Rundell

series ordinal

2

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22 September 2017

Zoltán N Oltvai

series ordinal

3

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22 September 2017

publication date

1 April 2003

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Biochemical and Biophysical Research Communications

22 September 2017

published in

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22 September 2017

volume

303

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22 September 2017

issue

3

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22 September 2017

page(s)

800-807

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The serial cultivation of human diploid cell strains

22 September 2017

cites work

1 reference

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

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A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

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Breaking the mitochondrial barrier

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Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

7 January 2021

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Bax alpha perturbs T cell development and affects cell cycle entry of T cells

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Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors

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bcl-2 overexpression inhibits cell death and promotes the morphogenesis, but not tumorigenesis of human mammary epithelial cells

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The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

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Bcl-2 accelerates multistep prostate carcinogenesis in vivo

7 January 2021

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Extension of life-span by introduction of telomerase into normal human cells

7 January 2021

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Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

7 January 2021

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Critical role for SV40 small-t antigen in human cell transformation

7 January 2021

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

7 January 2021

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Sequential paraformaldehyde and methanol fixation for simultaneous flow cytometric analysis of DNA, cell surface proteins, and intracellular proteins

7 January 2021

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7 January 2021

Myc activates telomerase

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Primary cells suppress oncogene-dependent apoptosis

7 January 2021

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Bcl-2 can promote p53-dependent senescence versus apoptosis without affecting the G1/S transition

7 January 2021

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Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.

7 January 2021

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Interleukin-3 induces the phosphorylation of a distinct fraction of bcl-2.

7 January 2021

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Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation

7 January 2021

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bcl-2 protein in non-small-cell lung carcinoma

7 January 2021

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p53 and bcl-2 protein expression in non-small-cell lung carcinoma.

7 January 2021

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10.1016/S0006-291X(03)00402-9

7 January 2021

Identifiers

DOI

1 reference

22 September 2017

1 reference