(Q40659575)

22 September 2017

title

New homologous bioassays for human lactogens show that agonism or antagonism of various analogs is a function of assay sensitivity (English)

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22 September 2017

Sophie Bernichtein

1

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22 September 2017

Sébastien Jeay

2

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22 September 2017

Roland Vaudry

3

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22 September 2017

Paul A Kelly

4

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22 September 2017

Vincent Goffin

5

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22 September 2017

publication date

1 February 2003

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22 September 2017

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22 September 2017

volume

20

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22 September 2017

issue

1-2

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22 September 2017

page(s)

177-190

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Rational design of potent antagonists to the human growth hormone receptor

22 September 2017

cites work

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12 December 2020

A single phosphotyrosine residue of the prolactin receptor is responsible for activation of gene transcription

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12 December 2020

Isolation and characterization of two novel forms of the human prolactin receptor generated by alternative splicing of a newly identified exon 11.

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12 December 2020

A new sensitive and specific bioassay for lactogenic hormones: measurement of prolactin and growth hormone in human serum

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12 December 2020

Cytokine receptor signalling through two novel families of transducer molecules: Janus kinases, and signal transducers and activators of transcription

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12 December 2020

Prolactin receptor signal transduction in cells of the immune system

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12 December 2020

Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse

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12 December 2020

In vivo studies of the anti-tumor effects of a human prolactin antagonist, hPRL-G129R.

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12 December 2020

Bacterial production and purification of recombinant human prolactin

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12 December 2020

In vitro and in vivo studies of antagonistic effects of human growth hormone analogs.

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12 December 2020

The human growth hormone antagonist B2036 does not interact with the prolactin receptor

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12 December 2020

A prolactin-dependent immune cell line (Nb2) expresses a mutant form of prolactin receptor

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12 December 2020

Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes

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12 December 2020

Antagonistic properties of human prolactin analogs that show paradoxical agonistic activity in the Nb2 bioassay

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12 December 2020

Receptor-mediated mitogenic action of prolactin in a rat lymphoma cell line

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12 December 2020

Alanine-scanning mutagenesis of human prolactin: importance of the 58-74 region for bioactivity

1 reference

12 December 2020

S179D-human PRL, a pseudophosphorylated human PRL analog, is an agonist and not an antagonist

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12 December 2020

Prolactin as a mitogen in mammary cells

1 reference

12 December 2020

Identification of a cDNA encoding a long form of prolactin receptor in human hepatoma and breast cancer cells

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12 December 2020

Growth hormone prevents apoptosis through activation of nuclear factor-kappaB in interleukin-3-dependent Ba/F3 cell line

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12 December 2020

Development of recombinant human prolactin receptor antagonists by molecular mimicry of the phosphorylated hormone.

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12 December 2020

Mechanism of ruminant placental lactogen action: molecular and in vivo studies

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12 December 2020

The Nb2 form of prolactin receptor is able to activate a milk protein gene promoter

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12 December 2020

G120R, a human growth hormone antagonist, shows zinc-dependent agonist and antagonist activity on Nb2 cells

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12 December 2020

Pseudophosphorylated prolactin (S179D PRL) inhibits growth and promotes beta-casein gene expression in the rat mammary gland

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12 December 2020

Mechanism-based design of prolactin receptor antagonists.

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12 December 2020

Studies on the microheterogeneity and in vitro activity of glycosylated and nonglycosylated recombinant human prolactin separated using a novel purification process

1 reference

12 December 2020

Biological properties of human prolactin analogs depend not only on global hormone affinity, but also on the relative affinities of both receptor binding sites

1 reference

12 December 2020

Characterization of a novel and functional human prolactin receptor isoform (deltaS1PRLr) containing only one extracellular fibronectin-like domain

1 reference

12 December 2020

Inhibition of lactogenic activities of ovine prolactin and human growth hormone (hGH) by a novel form of a modified recombinant hGH.

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12 December 2020

Sequence-function relationships within the expanding family of prolactin, growth hormone, placental lactogen, and related proteins in mammals

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12 December 2020

Expression of two forms of prolactin receptor in rat ovary and liver

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12 December 2020

Bioactive recombinant methionyl bovine prolactin: structure-function studies using site-specific mutagenesis

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12 December 2020

Prolactin receptor antagonists that inhibit the growth of breast cancer cell lines

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12 December 2020

T47DCO cells, genetically unstable and containing estrogen receptor mutations, are a model for the progression of breast cancers to hormone resistance.

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12 December 2020

Human prolactin (hPRL) antagonists inhibit hPRL-activated signaling pathways involved in breast cancer cell proliferation

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12 December 2020

Identifiers

DOI

10.1385/ENDO:20:1-2:177

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Dimensions Publication ID

22 September 2017

1010695934

0 references

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