(Q40663020)

22 September 2017

Role of DNA polymerase eta in the UV mutation spectrum in human cells (English)

1 reference

22 September 2017

Anne Stary

1

1 reference

22 September 2017

Patricia Kannouche

series ordinal

2

1 reference

22 September 2017

Alan R Lehmann

series ordinal

3

1 reference

22 September 2017

Alain Sarasin

series ordinal

4

1 reference

22 September 2017

language of work or name

English

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publication date

18 March 2003

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

18767-18775

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22 September 2017

21

1 reference

Sunlight and the onset of skin cancer

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

The molecular pathways of ultraviolet-induced carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Distribution and repair of photolesions in DNA: genetic consequences and the role of sequence context

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

UV damage and repair mechanisms in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Individual determination of the yield of the main UV-induced dimeric pyrimidine photoproducts in DNA suggests a high mutagenicity of CC photolesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Molecular mechanism of nucleotide excision repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Mutagenicity of a unique thymine-thymine dimer or thymine-thymine pyrimidine pyrimidone (6-4) photoproduct in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Mutagenesis induced by single UV photoproducts in E. coli and yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

The (6-4) photoproduct of thymine-thymine induces targeted substitution mutations in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Specialized DNA polymerases, cellular survival, and the genesis of mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Replication of UV-damaged DNA: new insights into links between DNA polymerases, mutagenesis and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Translesion synthesis by the UmuC family of DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

A plethora of lesion-replicating DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Error-prone repair DNA polymerases in prokaryotes and eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Managing DNA polymerases: coordinating DNA replication, DNA repair, and DNA recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Developmental control of cell cycle regulators: a fly's perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Low fidelity DNA synthesis by human DNA polymerase-eta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

The Y-family of DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Mechanisms of accurate translesion synthesis by human DNA polymerase eta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

hRAD30 mutations in the variant form of xeroderma pigmentosum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Abnormal, error-prone bypass of photoproducts by xeroderma pigmentosum variant cell extracts results in extreme strand bias for the kinds of mutations induced by UV light

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Xeroderma pigmentosum variant cells are less likely than normal cells to incorporate dAMP opposite photoproducts during replication of UV-irradiated plasmids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Evidence from mutation spectra that the UV hypermutability of xeroderma pigmentosum variant cells reflects abnormal, error-prone replication on a template containing photoproducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Ultraviolet hypermutability of a shuttle vector propagated in xeroderma pigmentosum variant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Xeroderma pigmentosum cells with normal levels of excision repair have a defect in DNA synthesis after UV-irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Replication fork bypass of a pyrimidine dimer blocking leading strand DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Bypass of a site-specific cis-Syn thymine dimer in an SV40 vector during in vitro replication by HeLa and XPV cell-free extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

A single (6-4) photoproduct inhibits plasmid DNA replication in xeroderma pigmentosum variant cell extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Impaired translesion synthesis in xeroderma pigmentosum variant extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

DNA polymerase eta undergoes alternative splicing, protects against UV sensitivity and apoptosis, and suppresses Mre11-dependent recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Complementation of defective translesion synthesis and UV light sensitivity in xeroderma pigmentosum variant cells by human and mouse DNA polymerase eta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Characteristics of UV-induced mutation spectra in human XP-D/ERCC2 gene-mutated xeroderma pigmentosum and trichothiodystrophy cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Description of a new amplifiable shuttle vector for mutagenesis studies in human cells: application to N-methyl-N'-nitro-N-nitrosoguanidine-induced mutation spectrum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Simian virus 40 (SV40) large T antigen-dependent amplification of an Epstein-Barr virus-SV40 hybrid shuttle vector integrated into the human HeLa cell genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Statistical test for the comparison of samples from mutational spectra

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase eta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase iota

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Role of RecA protein in untargeted UV mutagenesis of bacteriophage lambda: evidence for the requirement for the dinB gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Mutation enhancement by DINB1, a mammalian homologue of the Escherichia coli mutagenesis protein dinB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Requirement of DNA polymerase eta for error-free bypass of UV-induced CC and TC photoproducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

TP53 mutations in human skin cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Biochemical characterization of human DNA polymeraseiprovides clues to its biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Frequency of ultraviolet light-induced mutations is higher in xeroderma pigmentosum variant cells than in normal human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Error-Prone DNA Polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Fidelity of human DNA polymerase eta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

Genotoxic evaluation of three heterocyclic N-methylcarbamate pesticides using the mouse bone marrow micronucleus assay and the Saccharomyces cerevisiae strains D7 and D61.M.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211838200

21 January 2018

Identifiers

DOI

10.1074/JBC.M211838200

1 reference

22 September 2017

1 reference